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Index > Protein center > Unc45b(Gene name) > Mouse
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  • Unc45b (Gene name),
  • Protein unc-45 homolog B (Protein name ),  UN45B_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Unc45b(Cmya4);
    Protein name:
    Protein unc-45 homolog B(Unc-45B);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with HSP90 in an ATP-independent manner.
    Function:
    Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development.
    Subcellular Location:
    Cytoplasm cytosol
    Protein Attributes:
    Sequence length:
    931
    Sequence:
    50:
    MAEAEAAQLK | EEGNRHFQLQ | DYKAATKSYS | QALKLTKDKA | LLATLYRNRA | 
    100:
    ACGLKMESYA | QAASDASRAI | DINSADIKAL | YRRCQALEHL | GKLDQAFKDV | 
    150:
    QRCATLEPRN | QNFQETLRRL | NTSIQEQLRV | QFSTDSRVQT | MFEILLNENS | 
    200:
    EADKREKAAN | NLIVLGREEA | GAERIFQSNG | VALLLQLMNT | QRPELLLAAV | 
    250:
    RTLSGMCSGH | RARATAILHA | VRIDRICSLM | ALENEEMSLA | VCNLLQAIID | 
    300:
    SLSGEDKREH | RGKEEALVLD | TKKDLKQITS | HLLDMLVSKK | VSGQGRDQAL | 
    350:
    NLLNKNVPRK | DLSIHDNSRT | IYVVDNGLRK | ILKVVGQVPD | LPSCLPLTDN | 
    400:
    TRMLASILIN | KLYDDLRCDP | ERDHFRKICE | EYITSKFDPQ | DMDKNVNAIQ | 
    450:
    TVSGILQGPF | DLGNQLLGMK | GVMEMMVALC | GSEREADQLV | AVEALIHAST | 
    500:
    KLSRATFIIT | NGVTLLKQIY | KTTKNEKIKI | RTLVGLCKLG | SAGGSDYGLR | 
    550:
    QFAEGSTEKL | AKQCRKWLCN | TAIDTRTRRW | AVEGLAYLTL | DADVKDDFVQ | 
    600:
    DIPALQAMFE | LAKARTSDKT | ILYSVANTLV | NCTNSYDVKE | VVPELVQLAK | 
    650:
    FSKQHVPEEH | PKDKKDFVDL | RVKRLLKAGV | ISALACMVKA | DSAILTDQTK | 
    700:
    ELLARVFLAL | CDNPKDRGTI | VAQGGGKALI | PLALEGTDVG | KVKAAHGLAK | 
    750:
    IAAVSNPDIA | FPGERVYEVV | RPLVSLLDTQ | RDGLQNYEAL | LGLTNLSGRS | 
    800:
    DKLRQKIFKE | KALPDIENYM | FENHDQLRQA | ATECMCNMVL | NKEVQERFLA | 
    850:
    DGNDRLKLVV | LLCGEDDHKL | QNAAAGALAM | LTAAHKKLCL | KMTEVTTQWL | 
    900:
    EILQRLCLHD | QLSVQHRGLV | IAHNLLSADA | ELARKLVESE | LLEILTVVGK | 
    931:
    QEPDEKRAAV | VQTARECLIK | CMDYGFIKPV | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Unc-45B
    ELISA Kit for Mouse Unc-45B
    CLIA Kit for Mouse Unc-45B
    CLIA Kit for Mouse Unc-45B
    Polyclonal Antibody for Mouse Unc-45B
    Polyclonal Antibody for Mouse Unc-45B
    Monoclonal Antibody for Mouse Unc-45B
    Monoclonal Antibody for Mouse Unc-45B
    Protein for Mouse Unc-45B
    Protein for Mouse Unc-45B

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions."
      Price M.G. , Landsverk M.L. , Barral J.M. , Epstein H.F.
      J. Cell Sci.115:4013-4023(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY
      strain: C57BL/6J.
      tissue: Embryo.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Embryonic eye.
      tissue: Embryonic head.
      tissue: Embryonic heart.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Embryo.
    5. 5.
      "Unc45 activates Hsp90-dependent folding of the myosin motor domain."
      Liu L. , Srikakulam R. , Winkelmann D.A.
      J. Biol. Chem.283:13185-13193(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HSP90
    6. 6.
      "Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain."
      Srikakulam R. , Liu L. , Winkelmann D.A.
      PLoS ONE3:E2137-E2137(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH HSP90
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