Gene name:
Uncx (Uncx4.1) ;
Protein name:
Homeobox protein unc-4 homolog ;
Alternative:
Homeobox protein Uncx4.1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MMDGRLLEHP | HAQFGGSLGG | VVGFPYPLGH | HHVYELAGHQ | LQSAAAAAAA |
100:
ASVPFSIDGL | LSGSCAAAAA | SVVNPTPLLP | AACGVAGESQ | PFKLADSGDP |
150:
DKESPGCKRR | RTRTNFTGWQ | LEELEKAFNE | SHYPDVFMRE | ALALRLDLVE |
200:
SRVQVWFQNR | RAKWRKKENT | KKGPGRPAHN | SHPTTCSGEP | MDPEEIARKE |
250:
LEKMEKKKRK | HEKKLLKSQS | RHLHSPGGLS | LHSAPSSDSD | SGGGGLSPEP |
300:
PEPPPPTAAA | KGPGAHGSGI | AGSAPVPPGE | PPAPGTCDPA | FYPSQRSGAG |
350:
SQPRLGRPAD | KDTVPCGPGA | AATAGLPKAS | PFSVESLLSD | SPPRRKATPA |
400:
NAAATAGLDF | TPGLPCAPRT | LIGKGHFLLY | PITQPLGFLV | PQAALKGGAG |
450:
PELVPKDAPP | APPAPPAPPA | QASFGTFPGP | GGAADPAFAR | RSPEVVASPG |
500:
PPAPASFRDL | TAAAAESGAG | DCADVGTVCP | AASPPPPLET | SPGPGPRAPS |
530:
PPGEPATCGA | AEPGAATGPS | PPEGEEVDMD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse Homeobox protein unc-4 homolog
ELISA Kit for Mouse Homeobox protein unc-4 homolog
ELISA Kit for Mouse Homeobox protein unc-4 homolog
CLIA Kit for Mouse Homeobox protein unc-4 homolog
CLIA Kit for Mouse Homeobox protein unc-4 homolog
CLIA Kit for Mouse Homeobox protein unc-4 homolog
Polyclonal Antibody for Mouse Homeobox protein unc-4 homolog
Polyclonal Antibody for Mouse Homeobox protein unc-4 homolog
Polyclonal Antibody for Mouse Homeobox protein unc-4 homolog
Monoclonal Antibody for Mouse Homeobox protein unc-4 homolog
Monoclonal Antibody for Mouse Homeobox protein unc-4 homolog
Monoclonal Antibody for Mouse Homeobox protein unc-4 homolog
Protein for Mouse Homeobox protein unc-4 homolog
Protein for Mouse Homeobox protein unc-4 homolog
Protein for Mouse Homeobox protein unc-4 homolog
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DISRUPTION PHENOTYPE
2.
"Cloning and expression of the mouse homolog of Caenorhabditis elegans unc4 gene."
Nicholson L.F.B.
,
Ma L.
,
Goulding M.
Submitted (2000-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Spinal cord .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-387;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain :
C57BL/6 .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 109-304
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
14.
"Ripply2 is essential for precise somite formation during mouse early development."
Chan T.
,
Kondow A.
,
Hosoya A.
,
Hitachi K.
,
Yukita A.
,
Okabayashi K.
,
Nakamura H.
,
Ozawa H.
,
Kiyonari H.
,
Michiue T.
,
Ito Y.
,
Asashima M.
FEBS Lett.581:2691-2696(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY