PLAUR ELISA Kit for Human(Homo sapiens) | EIAab.comPLAUR ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > PLAUR(Gene name) > Human

PLAUR (Gene name),

Urokinase plasminogen activator surface receptor (Protein name ), UPAR_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

PLAUR(MO3;UPAR);

Protein name:

Urokinase plasminogen activator surface receptor(U-PAR;uPAR);

Alternative:

Monocyte activation antigen Mo3;

CD:

CD87;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2.

Function:

Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

Subcellular Location:

Isoform 2 Secreted

Protein Attributes:

Sequence length:

335

Sequence:

50:

100:

150:

200:

250:

300:

335:

QYRSGAAPQP | GPAHLSLTIT | LLMTARLWGG | TLLWT

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Hs.466871

String:

Q03405

SMR:

Q03405

KEGG:

hsa:5329

MIM:

173391

Pfam:

PF00021

Uniprot:

Q03405

FOR

ELISA Kit for Human U-PAR

Cat.:

E0141h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human U-PAR

Cat.:

E0141m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human U-PAR

Cat.:

E0141r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human U-PAR

Cat.:

E0141b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human U-PAR

Cat.:

U0141m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human U-PAR

Cat.:

U0141h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human U-PAR

Cat.:

U0141b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human U-PAR

Cat.:

U0141r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human U-PAR

Cat.:

P0141Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human U-PAR

Cat.:

P0141Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human U-PAR

Cat.:

P0141Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human U-PAR

Protein for Human U-PAR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis."
Roldan A.L. , Cubellis M.V. , Masucci M.T. , Behrendt N. , Lund L.R. , Danoe K. , Appella E. , Blasi F.
EMBO J.9:467-474(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 23-33
2.

"cDNA for Mo3, a monocyte activation antigen, encodes the human receptor for urokinase plasminogen activator."
Min H.Y. , Semnani R. , Mizukami I.F. , Watt K. , Todd R.F. III , Liu D.Y.
J. Immunol.148:3636-3642(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"A novel urokinase receptor on monocyte-like macrophage cell line."
Bayraktutan U. , Jones P.
Biochem. Soc. Trans.21:395-395(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
4.

"An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator."
Pyke C. , Eriksen J. , Solberg H. , Schnack Nielsen B. , Kristensen P. , Lund L.R. , Danoe K.
FEBS Lett.326:69-74(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
5.

"The structure of the urokinase-type plasminogen activator receptor gene."
Casey J.R. , Petranka J.G. , Kottra J. , Fleenor D.E. , Rosse W.F.
Blood84:1151-1156(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 3)
tissue: Placenta.
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
8.

SeattleSNPs variation discovery resource
Submitted (2002-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLY-55; ALA-86; GLN-105; ARG-220; LYS-281 AND PRO-317
9.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Skin.
12.

"cDNA cloning and sequencing of human urokinase receptor."
Zhu F. , Jia S. , He F.
Sheng Wu Gong Cheng Xue Bao16:461-463(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-322 (ISOFORM 1)
tissue: Lung cancer.
13.

"Experimental study of anti-metastatic effect of soluble receptor for urokinase plasminogen activator on human breast cancer cells."
Fu J. , Bai X. , Wang W. , Xi X. , Ruan C.
Submitted (2001-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-301 (ISOFORM 1)
14.

"A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene."
Soravia E. , Grebe A. , De Luca P. , Helin K. , Suh T.T. , Degen J.L. , Blasi F.
Blood86:624-635(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-18
15.

"The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants."
Behrendt N. , Roenne E. , Ploug M. , Petri T. , Loeber D. , Nielsen L.S. , Schleuning W.-D. , Blasi F. , Appella E. , Danoe K.
J. Biol. Chem.265:6453-6460(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
16.

"Cell-surface acceleration of urokinase-catalyzed receptor cleavage."
Hoeyer-Hansen G. , Ploug M. , Behrendt N. , Roenne E. , Danoe K.
Eur. J. Biochem.243:21-26(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 106-116;CLEAVAGE BY U-PA
17.

"A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26)."
Duke-Cohan J.S. , Morimoto C. , Rocker J.A. , Schlossman S.F.
J. Biol. Chem.270:14107-14114(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 210-230 (ISOFORMS 1/2/3)
tissue: Serum.
18.

"Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins."
Ploug M. , Kjalke M. , Roenne E. , Weidle U. , Hoeyer-Hansen G. , Danoe K.
J. Biol. Chem.268:17539-17546(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;PARTIAL PROTEIN SEQUENCE
19.

"A urokinase receptor-associated protein with specific collagen binding properties."
Behrendt N. , Jensen O.N. , Engelholm L.H. , Moertz E. , Mann M. , Danoe K.
J. Biol. Chem.275:1993-2002(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MRC2
20.

"Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton."
Artym V.V. , Kindzelskii A.L. , Chen W.T. , Petty H.R.
Carcinogenesis23:1593-1601(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAP;SUBCELLULAR LOCATION
21.

"Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins."
Elortza F. , Nuehse T.S. , Foster L.J. , Stensballe A. , Peck S.C. , Jensen O.N.
Mol. Cell. Proteomics2:1261-1270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
22.

"LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration."
Zhu Y. , Bujo H. , Yamazaki H. , Ohwaki K. , Jiang M. , Hirayama S. , Kanaki T. , Shibasaki M. , Takahashi K. , Schneider W.J. , Saito Y.
Circ. Res.94:752-758(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SORL1
23.

"Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
Elortza F. , Mohammed S. , Bunkenborg J. , Foster L.J. , Nuehse T.S. , Brodbeck U. , Peck S.C. , Jensen O.N.
J. Proteome Res.5:935-943(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
24.

"Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR."
Royer-Zemmour B. , Ponsole-Lenfant M. , Gara H. , Roll P. , Leveque C. , Massacrier A. , Ferracci G. , Cillario J. , Robaglia-Schlupp A. , Vincentelli R. , Cau P. , Szepetowski P.
Hum. Mol. Genet.17:3617-3630(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRPX2
25.

"Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide."
Llinas P. , Le Du M.H. , Gaardsvoll H. , Danoe K. , Ploug M. , Gilquin B. , Stura E.A. , Menez A.
EMBO J.24:1655-1663(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 23-335 OF MUTANT GLN-222 IN COMPLEX WITH PEPTIDE ANTAGONIST;GLYCOSYLATION AT ASN-74; ASN-184; ASN-194 AND ASN-255;DISULFIDE BONDS
26.

"Structure of human urokinase plasminogen activator in complex with its receptor."
Huai Q. , Mazar A.P. , Kuo A. , Parry G.C. , Shaw D.E. , Callahan J. , Li Y. , Yuan C. , Bian C. , Chen L. , Furie B. , Furie B.C. , Cines D.B. , Huang M.
Science311:656-659(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 23-297 IN COMPLEX WITH PLAU;GLYCOSYLATION AT ASN-74 AND ASN-194;DISULFIDE BONDS
27.

"Crystal structure of the urokinase receptor in a ligand-free form."
Xu X. , Gardsvoll H. , Yuan C. , Lin L. , Ploug M. , Huang M.
J. Mol. Biol.416:629-641(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.39 ANGSTROMS) OF 23-305 OF MUTANT CYS-69 AND CYS-281 ALONE AND IN COMPLEX WITH PLAU;DISULFIDE BONDS;GLYCOSYLATION AT ASN-74 AND ASN-222

Product Feedback Wall

* Email:
*Comments: