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Index > Protein center > Upk1a(Gene name) > Mouse
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  • Upk1a (Gene name),
  • Uroplakin-1a (Protein name ),  UPK1A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Upk1a;
    Protein name:
    Uroplakin-1a(UP1a);
    Alternative:
    Uroplakin Ia(UPIa;UPKa);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with uroplakin-2 (UPK2) (By similarity). Binds to uropathogenic E.coli fimH.
    Function:
    Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    257
    Sequence:
    50:
    MASAATEGEK | GSPVVVGLLV | VGNIIILLSG | LALFAETVWV | TADQYRVYPL | 
    100:
    MGVSGKDDVF | AGAWIAIFCG | FSFFVVASFG | VGAALCRRRY | MILTYLLLML | 
    150:
    IVYIFECASC | ITSYTHRDYM | VSNPSLITKQ | MLTYYSADTD | QGQELTRLWD | 
    200:
    RIMIEQECCG | TSGPMDWVNY | TSAFRAATPE | VVFPWPPLCC | RRTGNFIPIN | 
    250:
    EDGCRVGHMD | YLFTKGCFEH | IGHAIDSYTW | GISWFGFAIL | MWTLPVMLIA | 
    257:
    MYFYTTL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse UP1a
    ELISA Kit for Mouse UP1a
    ELISA Kit for Mouse UP1a
    CLIA Kit for Mouse UP1a
    CLIA Kit for Mouse UP1a
    CLIA Kit for Mouse UP1a
    Polyclonal Antibody for Mouse UP1a
    Polyclonal Antibody for Mouse UP1a
    Polyclonal Antibody for Mouse UP1a
    Monoclonal Antibody for Mouse UP1a
    Monoclonal Antibody for Mouse UP1a
    Monoclonal Antibody for Mouse UP1a
    Protein for Mouse UP1a
    Protein for Mouse UP1a
    Protein for Mouse UP1a

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding."
      Zhou G. , Mo W.J. , Sebbel P. , Min G. , Neubert T.A. , Glockshuber R. , Wu X.R. , Sun T.T. , Kong X.P.
      J. Cell Sci.114:4095-4103(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH E.COLI FIMH
      tissue: Urinary bladder.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
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