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Index > Protein center > URM1(Gene name) > Human
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  • URM1 (Gene name),
  • Ubiquitin-related modifier 1 homolog (Protein name ),  URM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    URM1(C9orf74);
    Protein name:
    Ubiquitin-related modifier 1 homolog;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
    Function:
    Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    101
    Sequence:
    50:
    MAAPLSVEVE | FGGGAELLFD | GIKKHRVTLP | GQEEPWDIRN | LLIWIKKNLL | 
    100:
    KERPELFIQG | DSVRPGILVL | INDADWELLG | ELDYQLQDQD | SVLFISTLHG | 
    101:
    G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ubiquitin-related modifier 1 homolog
    ELISA Kit for Human Ubiquitin-related modifier 1 homolog
    ELISA Kit for Human Ubiquitin-related modifier 1 homolog
    ELISA Kit for Human Ubiquitin-related modifier 1 homolog
    CLIA Kit for Human Ubiquitin-related modifier 1 homolog
    CLIA Kit for Human Ubiquitin-related modifier 1 homolog
    CLIA Kit for Human Ubiquitin-related modifier 1 homolog
    CLIA Kit for Human Ubiquitin-related modifier 1 homolog
    Polyclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Polyclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Polyclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Polyclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Monoclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Monoclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Monoclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Monoclonal Antibody for Human Ubiquitin-related modifier 1 homolog
    Protein for Human Ubiquitin-related modifier 1 homolog
    Protein for Human Ubiquitin-related modifier 1 homolog
    Protein for Human Ubiquitin-related modifier 1 homolog
    Protein for Human Ubiquitin-related modifier 1 homolog

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Placenta.
      tissue: Small intestine.
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    5. 5.
      "A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway."
      Schlieker C.D. , Van der Veen A.G. , Damon J.R. , Spooner E. , Ploegh H.L.
      Proc. Natl. Acad. Sci. U.S.A.105:18255-18260(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN 2-THIOLATION OF TRNA;IDENTIFICATION IN A COMPLEX WITH CTU1 AND C16ORF84;THIOCARBOXYLATION AT GLY-101
    6. 6.
      "Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier."
      Van der Veen A.G. , Schorpp K. , Schlieker C. , Buti L. , Damon J.R. , Spooner E. , Ploegh H.L. , Jentsch S.
      Proc. Natl. Acad. Sci. U.S.A.108:1763-1770(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PROTEIN CONJUGATION;IDENTIFICATION OF SUBSTRATES
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