Ush1g ELISA Kit for Mouse(Mus musculus) | EIAab.comUsh1g ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Ush1g(Gene name) > Mouse

Ush1g (Gene name),

Usher syndrome type-1G protein homolog (Protein name ), USH1G_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ush1g(Sans);

Protein name:

Usher syndrome type-1G protein homolog;

Alternative:

Scaffold protein containing ankyrin repeats and SAM domain;Jackson shaker protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Associates with USH1C by binding to its first PDZ domain. Interacts with PDZD7.

Function:

Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

461

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

461:

ERPLALEDTE | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:16470

SMR:

Q80T11

Pfam:

PF12796

UniGene:

Mm.451539

String:

Q80T11

Uniprot:

Q80T11

FOR

ELISA Kit for Mouse Usher syndrome type-1G protein homolog

CLIA Kit for Mouse Usher syndrome type-1G protein homolog

Polyclonal Antibody for Mouse Usher syndrome type-1G protein homolog

Monoclonal Antibody for Mouse Usher syndrome type-1G protein homolog

Protein for Mouse Usher syndrome type-1G protein homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice."
Kikkawa Y. , Shitara H. , Wakana S. , Kohara Y. , Takada T. , Okamoto M. , Taya C. , Kamiya K. , Yoshikawa Y. , Tokano H. , Kitamura K. , Shimizu K. , Wakabayashi Y. , Shiroishi T. , Kominami R. , Yonekawa H.
Hum. Mol. Genet.12:453-461(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY;POSSIBLE FUNCTION
2.

"Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin."
Weil D. , El-Amraoui A. , Masmoudi S. , Mustapha M. , Kikkawa Y. , Laine S. , Delmaghani S. , Adato A. , Nadifi S. , Zina Z.B. , Hamel C. , Gal A. , Ayadi H. , Yonekawa H. , Petit C.
Hum. Mol. Genet.12:463-471(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH USH1C;POSSIBLE FUNCTION
3.

"Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia."
Caberlotto E. , Michel V. , Foucher I. , Bahloul A. , Goodyear R.J. , Pepermans E. , Michalski N. , Perfettini I. , Alegria-Prevot O. , Chardenoux S. , Do Cruzeiro M. , Hardelin J.P. , Richardson G.P. , Avan P. , Weil D. , Petit C.
Proc. Natl. Acad. Sci. U.S.A.108:5825-5830(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;INTERACTION WITH CDH23 AND PCDH15
4.

"Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction."
Grati M. , Kachar B.
Proc. Natl. Acad. Sci. U.S.A.108:11476-11481(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION

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