Protein name:
Urea transporter 2 ;
Alternative:
Urea transporter, kidney ;Solute carrier family 14 member 2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Isoform A1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.
Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Vasopressin regulates urea transport by increasing isoform A1 accumulation in the plasma membrane and/or phosphorylation of isoform A1.
Subcellular Location:
Apical cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSDHHPLKEM | SDSNSSPLLP | EPLSSRYKLY | ESELSSPTWP | SSSQDTHPAL |
100:
PLLEMPEEKD | LRSSDEDSHI | VKIEKPNERN | KRRESEVSRR | ASAGRGGFSL |
150:
FQAVSYLTGD | MKECKNWLKD | KPLVLQFLDW | VLRGAAQVMF | VNNPISGLII |
200:
FIGLLIQNPW | WTIAGTLGTV | ASTLAALALS | QDRSAIASGL | HGYNGMLVGL |
250:
LMAVFSEKLD | YYWWLLFPVT | FTSMACPIIS | SALSTIFAKW | DLPVFTLPFN |
300:
IALTLYLAAT | GHYNLFFPTT | LIKPASAAPN | ITWTEIEMPL | LLQTIPVGVG |
350:
QVYGCDNPWT | GGVILVALFI | SSPLICLHAA | IGSIVGLLAA | LTVATPFETI |
400:
YLGLWSYNCV | LSCIAIGGMF | YALTWQTHLL | ALVCALFCAY | MGAALSNTMA |
450:
VVGVPSGTWA | FCLSTLTFLL | LTSNNTGIYK | LPLSKVTYPE | ANRIYFLTVR |
500:
RSEEEKSPNG | GSGEQSHGSG | QWKAEESSET | VLPRRRSVFH | IEWSSIRRRS |
550:
KVFGKGEHQE | RQTKEPLPCP | YRKPTVELFD | LDTMEESTEI | KVEANTARTS |
600:
WIQSSMVAGG | KRVSKALSYI | TGEMKECGEG | LKDKSPVFQF | LDWVLRGMSQ |
650:
VMFVNNPLSG | ILIVLGLFVQ | NPWWAISGCL | GTVMSTLTAL | ILSQDKSAIA |
700:
AGLHGYNGVL | VGLLMAVFSD | KGNYYWWLLL | PVIVMSMTCP | ILSSALSTVF |
750:
SKWDLPVFTL | PFNIAVTLYL | AATGHHNLFF | PTTLLQPATT | TPNITWSDIQ |
800:
VSLLLRAIPV | GIGQVYGCDN | PWTGGIFLVA | LFISSPLICL | HAAIGSTIGM |
850:
LAALSIATPF | DSIYFGLCGF | NSTLACIAIG | GMFYVITWQT | HLLAIACALF |
900:
AAYLGAALAN | MLSVFGLPPC | TWPFCLSALT | FLLLTSNNPA | IYKLPLSKVT |
930:
YPEANRIYFL | SQEKNRRAST | ITKYQAYDVS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Rabbit
Human
ELISA Kit for Mouse Urea transporter 2
ELISA Kit for Mouse Urea transporter 2
ELISA Kit for Mouse Urea transporter 2
ELISA Kit for Mouse Urea transporter 2
CLIA Kit for Mouse Urea transporter 2
CLIA Kit for Mouse Urea transporter 2
CLIA Kit for Mouse Urea transporter 2
CLIA Kit for Mouse Urea transporter 2
Polyclonal Antibody for Mouse Urea transporter 2
Polyclonal Antibody for Mouse Urea transporter 2
Polyclonal Antibody for Mouse Urea transporter 2
Polyclonal Antibody for Mouse Urea transporter 2
Monoclonal Antibody for Mouse Urea transporter 2
Monoclonal Antibody for Mouse Urea transporter 2
Monoclonal Antibody for Mouse Urea transporter 2
Monoclonal Antibody for Mouse Urea transporter 2
Protein for Mouse Urea transporter 2
Protein for Mouse Urea transporter 2
Protein for Mouse Urea transporter 2
Protein for Mouse Urea transporter 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A3 AND A5);TISSUE SPECIFICITY (ISOFORM A5)
strain :
MF1 .
tissue :
Kidney inner medulla .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A1 AND A2)
strain :
MF1 .
tissue :
Kidney inner medulla .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A2);TISSUE SPECIFICITY
strain :
MF1 .
tissue :
Kidney inner medulla .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A1)
tissue :
Brain .