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Index > Protein center > Slc14a2(Gene name) > Mouse
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  • Slc14a2 (Gene name),
  • Urea transporter 2 (Protein name ),  UT2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc14a2(Ut2);
    Protein name:
    Urea transporter 2;
    Alternative:
    Urea transporter, kidney;Solute carrier family 14 member 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Isoform A1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.
    Function:
    Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Vasopressin regulates urea transport by increasing isoform A1 accumulation in the plasma membrane and/or phosphorylation of isoform A1.
    Subcellular Location:
    Apical cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    930
    Sequence:
    50:
    MSDHHPLKEM | SDSNSSPLLP | EPLSSRYKLY | ESELSSPTWP | SSSQDTHPAL | 
    100:
    PLLEMPEEKD | LRSSDEDSHI | VKIEKPNERN | KRRESEVSRR | ASAGRGGFSL | 
    150:
    FQAVSYLTGD | MKECKNWLKD | KPLVLQFLDW | VLRGAAQVMF | VNNPISGLII | 
    200:
    FIGLLIQNPW | WTIAGTLGTV | ASTLAALALS | QDRSAIASGL | HGYNGMLVGL | 
    250:
    LMAVFSEKLD | YYWWLLFPVT | FTSMACPIIS | SALSTIFAKW | DLPVFTLPFN | 
    300:
    IALTLYLAAT | GHYNLFFPTT | LIKPASAAPN | ITWTEIEMPL | LLQTIPVGVG | 
    350:
    QVYGCDNPWT | GGVILVALFI | SSPLICLHAA | IGSIVGLLAA | LTVATPFETI | 
    400:
    YLGLWSYNCV | LSCIAIGGMF | YALTWQTHLL | ALVCALFCAY | MGAALSNTMA | 
    450:
    VVGVPSGTWA | FCLSTLTFLL | LTSNNTGIYK | LPLSKVTYPE | ANRIYFLTVR | 
    500:
    RSEEEKSPNG | GSGEQSHGSG | QWKAEESSET | VLPRRRSVFH | IEWSSIRRRS | 
    550:
    KVFGKGEHQE | RQTKEPLPCP | YRKPTVELFD | LDTMEESTEI | KVEANTARTS | 
    600:
    WIQSSMVAGG | KRVSKALSYI | TGEMKECGEG | LKDKSPVFQF | LDWVLRGMSQ | 
    650:
    VMFVNNPLSG | ILIVLGLFVQ | NPWWAISGCL | GTVMSTLTAL | ILSQDKSAIA | 
    700:
    AGLHGYNGVL | VGLLMAVFSD | KGNYYWWLLL | PVIVMSMTCP | ILSSALSTVF | 
    750:
    SKWDLPVFTL | PFNIAVTLYL | AATGHHNLFF | PTTLLQPATT | TPNITWSDIQ | 
    800:
    VSLLLRAIPV | GIGQVYGCDN | PWTGGIFLVA | LFISSPLICL | HAAIGSTIGM | 
    850:
    LAALSIATPF | DSIYFGLCGF | NSTLACIAIG | GMFYVITWQT | HLLAIACALF | 
    900:
    AAYLGAALAN | MLSVFGLPPC | TWPFCLSALT | FLLLTSNNPA | IYKLPLSKVT | 
    930:
    YPEANRIYFL | SQEKNRRAST | ITKYQAYDVS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Urea transporter 2
    ELISA Kit for Mouse Urea transporter 2
    ELISA Kit for Mouse Urea transporter 2
    ELISA Kit for Mouse Urea transporter 2
    CLIA Kit for Mouse Urea transporter 2
    CLIA Kit for Mouse Urea transporter 2
    CLIA Kit for Mouse Urea transporter 2
    CLIA Kit for Mouse Urea transporter 2
    Polyclonal Antibody for Mouse Urea transporter 2
    Polyclonal Antibody for Mouse Urea transporter 2
    Polyclonal Antibody for Mouse Urea transporter 2
    Polyclonal Antibody for Mouse Urea transporter 2
    Monoclonal Antibody for Mouse Urea transporter 2
    Monoclonal Antibody for Mouse Urea transporter 2
    Monoclonal Antibody for Mouse Urea transporter 2
    Monoclonal Antibody for Mouse Urea transporter 2
    Protein for Mouse Urea transporter 2
    Protein for Mouse Urea transporter 2
    Protein for Mouse Urea transporter 2
    Protein for Mouse Urea transporter 2

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular characterization of a novel UT-A urea transporter isoform (UT-A5) in testis."
      Fenton R.A. , Howorth A. , Cooper G.J. , Meccariello R. , Morris I.D. , Smith C.P.
      Am. J. Physiol.279:C1425-C1431(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A3 AND A5);TISSUE SPECIFICITY (ISOFORM A5)
      strain: MF1.
      tissue: Kidney inner medulla.
      tissue: Testis.
    2. 2.
      "Structure and characterization of the mouse UT-A gene (Slc14a2)."
      Fenton R.A. , Cottingham C.A. , Stewart G.S. , Howorth A. , Hewitt J.A. , Smith C.P.
      Am. J. Physiol.282:F630-F638(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A1 AND A2)
      strain: MF1.
      tissue: Kidney inner medulla.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A2);TISSUE SPECIFICITY
      strain: MF1.
      tissue: Kidney inner medulla.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A1)
      tissue: Brain.
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