Slc14a2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSlc14a2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Slc14a2(Gene name) > Rat

Slc14a2 (Gene name),

Urea transporter 2 (Protein name ), UT2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc14a2(Ut2);

Protein name:

Urea transporter 2;

Alternative:

Urea transporter, kidney;Solute carrier family 14 member 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.

Function:

Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Vasopressin regulates urea transport by increasing isoform 1 accumulation in the plasma membrane and/or phosphorylation of isoform 1.

Subcellular Location:

Apical cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

929

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

929:

PEANRIYFLS | QEKNRRASMI | TKYQAYDVS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q62668

UniGene:

Rn.10157

KEGG:

rno:54302

Pfam:

PF03253

Uniprot:

Q62668

FOR

ELISA Kit for Rat Urea transporter 2

CLIA Kit for Rat Urea transporter 2

Polyclonal Antibody for Rat Urea transporter 2

Monoclonal Antibody for Rat Urea transporter 2

Protein for Rat Urea transporter 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Cloning and regulation of expression of the rat kidney urea transporter (rUT2)."
Smith C.P. , Lee W.-S. , Martial S. , Knepper M.A. , You G. , Sands J.M. , Hediger M.A.
J. Clin. Invest.96:1556-1563(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;INDUCTION
strain: Sprague-Dawley.
tissue: Kidney.
2.

"Molecular cloning and characterization of the vasopressin-regulated urea transporter of rat kidney collecting ducts."
Shayakul C. , Steel A. , Hediger M.A.
J. Clin. Invest.98:2580-2587(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Kidney inner medulla.
3.

"Cloning and characterization of two new isoforms of the rat kidney urea transporter: UT-A3 and UT-A4."
Karakashian A. , Timmer R.T. , Klein J.D. , Gunn R.B. , Sands J.M. , Bagnasco S.M.
J. Am. Soc. Nephrol.10:230-237(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);FUNCTION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Kidney inner medulla.
4.

"Molecular characterization of a novel urea transporter from kidney inner medullary collecting ducts."
Shayakul C. , Tsukaguchi H. , Berger U.V. , Hediger M.A.
Am. J. Physiol.280:F487-F494(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Kidney.
5.

"Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts."
Klein J.D. , Froehlich O. , Blount M.A. , Martin C.F. , Smith T.D. , Sands J.M.
J. Am. Soc. Nephrol.17:2680-2686(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;PHOSPHORYLATION
6.

"Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-486;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein."
Mistry A.C. , Mallick R. , Froehlich O. , Klein J.D. , Rehm A. , Chen G. , Sands J.M.
J. Biol. Chem.282:30097-30106(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNAPIN;SUBCELLULAR LOCATION

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