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Index > Protein center > Vangl2(Gene name) > Rat
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  • Vangl2 (Gene name),
  • Vang-like protein 2 (Protein name ),  VANG2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Vangl2;
    Protein name:
    Vang-like protein 2;
    Alternative:
    Van Gogh-like protein 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction. Also interacts with the PDZ domains of MAGI3, SCRIB/SCRB1 and FZD3.
    Function:
    Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    521
    Sequence:
    50:
    MDTESQYSGY | SYKSGHSRSS | RKHRDRRDRH | RSKSRDGSRG | DKSVTIQAPG | 
    100:
    EPLLDNESTR | GDERDDNWGE | TTTVVTGTSE | HSISHDDLTR | IAKDMEDSVP | 
    150:
    LDCSRHLGVA | AGAILALLSF | LTPLAFLLLP | PLLWREELEP | CGTACEGLFI | 
    200:
    SVAFKLLILL | LGSWALFFRR | PKASLPRVFV | LRALLMVLVF | LLVISYWLFY | 
    250:
    GVRILDARER | SYQGVVQFAV | SLVDALLFVH | YLAVVLLELR | QLQPQFTLKV | 
    300:
    VRSTDGASRF | YNVGHLSIQR | VAVWILEKYY | HDFPVYNPAL | LNLPKSVLAK | 
    350:
    KVSGFKVYSL | GEENSTNNST | GQSRAVIAAA | ARRRDNSHNE | YYYEEAEHER | 
    400:
    RVRKRRARLV | VAVEEAFTHI | KRLQEEEQKN | PREVMDPREA | AQAIFASMAR | 
    450:
    AMQKYLRTTK | QQPYHTMESI | LQHLEFCITH | DMTPKAFLER | YLAAGPTIQY | 
    500:
    HKERWLAKQW | TLVSEEPVTN | GLKDGIVFLL | KRQDFSLVVS | TKKVPFFKLS | 
    521:
    EEFVDPKSHK | FVMRLQSETS | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Vang-like protein 2
    Cat.:
    E15196h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Vang-like protein 2
    Cat.:
    E15196r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Vang-like protein 2
    Cat.:
    E15196m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Vang-like protein 2
    Cat.:
    U15196m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Vang-like protein 2
    Cat.:
    U15196h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Vang-like protein 2
    Cat.:
    U15196r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Vang-like protein 2
    Cat.:
    P15196Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Vang-like protein 2
    Cat.:
    P15196Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Vang-like protein 2
    Cat.:
    P15196Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Vang-like protein 2
    Monoclonal Antibody for Rat Vang-like protein 2
    Monoclonal Antibody for Rat Vang-like protein 2
    Protein for Rat Vang-like protein 2
    Protein for Rat Vang-like protein 2
    Protein for Rat Vang-like protein 2

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals."
      Montcouquiol M. , Sans N. , Huss D. , Kach J. , Dickman J.D. , Forge A. , Rachel R.A. , Copeland N.G. , Jenkins N.A. , Bogani D. , Murdoch J. , Warchol M.E. , Wenthold R.J. , Kelley M.W.
      J. Neurosci.26:5265-5275(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
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