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Index > Protein center > Vapa(Gene name) > Rat
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  • Vapa (Gene name),
  • Vesicle-associated membrane protein-associated protein A (Protein name ),  VAPA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Vapa(Vap33);
    Protein name:
    Vesicle-associated membrane protein-associated protein A(VAMP-A;VAMP-associated protein A;VAP-A);
    Alternative:
    33 kDa VAMP-associated protein(VAP-33);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer, and heterodimer with VAPB. Interacts with VAMP1, VAMP2, STX1A, BET1, SEC22C and with the C-terminal domain of OCLN (By similarity). Interacts with OSBPL1A. Interacts (via MSP domain) with ZFYVE27; may retain ZFYVE27 in the endoplasmic reticulum and regulate its function in cell projections formation.
    Function:
    May play a role in vesicle trafficking.
    Subcellular Location:
    Endoplasmic reticulum membrane Single-pass type IV membrane protein Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells.
    Protein Attributes:
    Sequence length:
    249
    Sequence:
    50:
    MASASGAMAK | HEQILVLDPP | SDLKFKGPFT | DVVTTNLKLQ | NPSDRKVCFK | 
    100:
    VKTTAPRRYC | VRPNSGVIDP | GSIVTVSVML | QPFDYDPNEK | SKHKFMVQTI | 
    150:
    FAPPNISDME | AVWKEAKPDE | LMDSKLRCVF | EMPNENDKLN | DMEPSKAVPL | 
    200:
    NASKQDGPLP | KPHSVSLNDT | ETRKLMEECK | RLQGEMMKLS | EENRHLRDEG | 
    249:
    LRLRKVAHSD | KPGSTSAVSF | RDNVTSPLPS | LLVVIAAIFI | GFFLGKFIL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat VAMP-A
    ELISA Kit for Rat VAMP-A
    ELISA Kit for Rat VAMP-A
    ELISA Kit for Rat VAMP-A
    CLIA Kit for Rat VAMP-A
    CLIA Kit for Rat VAMP-A
    CLIA Kit for Rat VAMP-A
    CLIA Kit for Rat VAMP-A
    Polyclonal Antibody for Rat VAMP-A
    Polyclonal Antibody for Rat VAMP-A
    Polyclonal Antibody for Rat VAMP-A
    Polyclonal Antibody for Rat VAMP-A
    Monoclonal Antibody for Rat VAMP-A
    Monoclonal Antibody for Rat VAMP-A
    Monoclonal Antibody for Rat VAMP-A
    Monoclonal Antibody for Rat VAMP-A
    Protein for Rat VAMP-A
    Protein for Rat VAMP-A
    Protein for Rat VAMP-A
    Protein for Rat VAMP-A

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    Precision
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    Linearity
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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    2. 2.
      "Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins."
      Nishimura Y. , Hayashi M. , Inada H. , Tanaka T.
      Biochem. Biophys. Res. Commun.254:21-26(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-249
      tissue: Heart.
    3. 3.
      "Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein."
      Saita S. , Shirane M. , Natume T. , Iemura S. , Nakayama K.I.
      J. Biol. Chem.284:13766-13777(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ZFYVE27
    4. 4.
      "Structural basis of FFAT motif-mediated ER targeting."
      Kaiser S.E. , Brickner J.H. , Reilein A.R. , Fenn T.D. , Walter P. , Brunger A.T.
      Structure13:1035-1045(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 8-132 IN COMPLEX WITH OSBPL1A;MUTAGENESIS OF LYS-94 AND MET-96
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