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Index > Protein center > Vav1(Gene name) > Rat
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  • Vav1 (Gene name),
  • Proto-oncogene vav (Protein name ),  VAV_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Vav1(Vav);
    Protein name:
    Proto-oncogene vav;
    Alternative:
    p95;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA, TEC and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK. May interact with CCPG1 (By similarity). Interacts with THEMIS2 (By similarity). Interacts with NEK3 and this interaction is prolactin-dependent. Interacts with ITK.
    Function:
    Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    843
    Sequence:
    50:
    MELWRQCTHW | LIQCRVLPPS | HRVTWEGAQV | CELAQALRDG | VLLCQLLNNL | 
    100:
    LPHAINLREV | NLRPQMSQFL | CLKNIRTFLS | TCCEKFGLKR | SELFEAFDLF | 
    150:
    DVQDFGKVIY | TLSALSWTPI | AQNKGIMPFP | TEDSALGDED | IYSGLSDQID | 
    200:
    DTAEEDEDLY | DCVENEEAEG | DEIYEDLMRS | ESVPTPPKMT | EYDKRCCCLR | 
    250:
    EIQQTEEKYT | DTLGSIQQHF | MKPLQRFLKP | QDMETIFVNI | EELLSVHTHF | 
    300:
    LKELKDALSG | PGATMLYQVF | IKYKERFLVY | GRYCSQVESA | IKHLDQVATA | 
    350:
    REDVQMKLEE | CSQRANNGRF | TLRDLLMVPM | QRVLKYHLLL | QELVKHTQDT | 
    400:
    TEKENLRLAL | DAMRDLAQCV | NEVKRDNETL | RQITNFQLSI | ENLDQSLANY | 
    450:
    GRPKIDGELK | ITSVERRSKT | DRYAFLLDKA | LLICKRRGDS | YDLKASVNLH | 
    500:
    SFQVRDDSSG | ERDNKKWSHM | FLLIEDQGAQ | GYELFFKTRE | LKKKWMEQFE | 
    550:
    MAISNIYPEN | ATANGHDFQM | FSFEETTSCK | ACQMLLRGTF | YQGYRCYRCR | 
    600:
    APAHKECLGR | VPPCGRQDFS | GTMKKDKLHR | RAQDKKRNEL | GLPKMEVCQE | 
    650:
    YYGIPPPPGA | FGPFLRLNPG | DIVELTKAEA | EHTWWEGRNT | ATNEVGWFPC | 
    700:
    NRVRPYVHGP | PQDLSVHLWY | AGPMERAGAE | GILTNRSDGT | YLVRQRVKDT | 
    750:
    AEFAISIKYN | VEVKHIKIMT | SEGLYRITEK | KAFRGLPELV | EFYQQNSLKD | 
    800:
    CFKSLDTTLQ | FPYKEPERRA | INKPPVGSTK | YFGTAKARYD | FCARDRSELS | 
    843:
    LKEGDIIKIL | NKKGQQGWWR | GEIYGRIGWF | PSNYVEEDYS | EYC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Proto-oncogene vav
    ELISA Kit for Rat Proto-oncogene vav
    ELISA Kit for Rat Proto-oncogene vav
    ELISA Kit for Rat Proto-oncogene vav
    CLIA Kit for Rat Proto-oncogene vav
    CLIA Kit for Rat Proto-oncogene vav
    CLIA Kit for Rat Proto-oncogene vav
    CLIA Kit for Rat Proto-oncogene vav
    Polyclonal Antibody for Rat Proto-oncogene vav
    Polyclonal Antibody for Rat Proto-oncogene vav
    Polyclonal Antibody for Rat Proto-oncogene vav
    Polyclonal Antibody for Rat Proto-oncogene vav
    Monoclonal Antibody for Rat Proto-oncogene vav
    Monoclonal Antibody for Rat Proto-oncogene vav
    Monoclonal Antibody for Rat Proto-oncogene vav
    Monoclonal Antibody for Rat Proto-oncogene vav
    Protein for Rat Proto-oncogene vav
    Protein for Rat Proto-oncogene vav
    Protein for Rat Proto-oncogene vav
    Protein for Rat Proto-oncogene vav

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    Precision
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    References
    1. 1.
      "Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway."
      Song J.S. , Haleem-Smith H. , Arudchandran R. , Gomez J. , Scott P.M. , Mill J.F. , Tan T.-H. , Rivera J.
      J. Immunol.163:802-810(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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