Gene name:
Flt4 (Flt-4;Vegfr3) ;
Protein name:
Vascular endothelial growth factor receptor 3 (VEGFR-3) ;
Alternative:
Tyrosine-protein kinase receptor FLT4 ;Fms-like tyrosine kinase 4 (FLT-4) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with PTPN14; the interaction is enhanced by stimulation with VEGFC.
Function:
Receptor for VEGFC. Has a tyrosine-protein kinase activity.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MQPGAALNLR | LWLCLGLLQG | LANGYSMTPP | TLNITEDSYV | IDTGDSLSIS |
100:
CRGQHPLEWT | WPGAQEVLTT | GGKDSEDTRV | VHDCEGTEAR | PYCKVLLLAQ |
150:
THANNTGSYH | CYYKYIKARI | EGTTAASTYV | FVRDFKHPFI | NKPDTLLVNR |
200:
KDSMWVPCLV | SIPGLNITLR | SQSSALHPDG | QEVLWDDRRG | MRVPTQLLRD |
250:
ALYLQCETTW | GDQNFLSNLF | VVHITGNELY | DIQLYPKKSM | ELLVGEKLVL |
300:
NCTVWAEFDS | GVTFDWDYPG | KQAERAKWVP | ERRSQQTHTE | LSSILTIHNV |
350:
SQNDLGPYVC | EANNGIQRFR | ESTEVIVHEK | PFISVEWLKG | PVLEATAGDE |
400:
LVKLPVKLAA | YPPPEFQWYK | DRKAVTGRHN | PHALVLKEVT | EASAGVYTLA |
450:
LWNSAAGLRQ | NISLELVVNV | PPHIHEKEAS | SPSIYSRHSR | QTLTCTAYGV |
500:
PQPLSVQWHW | RPWTPCKTFA | QRSLRRRQQR | DGMPQCRDWK | EVTTQDAVNP |
550:
IESLDSWTEF | VEGKNKTVSK | LVIQDANVSA | MYKCVVVNKV | GQDERLIYFY |
600:
VTTIPDGFSI | ESEPSEDPLE | GQSVRLSCRA | DNYTYEHLRW | YRLNLSTLHD |
650:
AQGNPLLLDC | KNVHLFATPL | EANLEEAEPG | ARHATLSLNI | PRVAPEDEGD |
700:
YVCEVQDRRS | QDKHCHKKYL | SVQALEAPRL | TQNLTDLLVN | VSDSLEMRCP |
750:
VAGAHVPSIV | WYKDERLLEK | ESGIDLADSN | QRLSIQRVRE | EDAGRYLCSV |
800:
CNAKGCVNSS | ASVAVEGSED | KGSMEIVILI | GTGVIAVFFW | VLLLLIFCNM |
850:
KRPAHADIKT | GYLSIIMDPG | EVPLEEQCEY | LSYDASQWEF | PRERLHLGRV |
900:
LGHGAFGKVV | EASAFGINKG | SSCDTVAVKM | LKEGATASEH | RALMSELKIL |
950:
IHIGNHLNVV | NLLGACTKPN | GPLMVIVEFC | KYGNLSNFLR | VKRDTFNPYA |
1000:
EKSPEQRRRF | RAMVEGAKAD | RRRPGSSDRA | LFTRFLMGKG | SARRAPLVQE |
1050:
AEDLWLSPLT | MEDLVCYSFQ | VARGMEFLAS | RKCIHRDLAA | RNILLSESDI |
1100:
VKICDFGLAR | DIYKDPDYVR | KGSARLPLKW | MAPESIFDKV | YTTQSDVWSF |
1150:
GVLLWEIFSL | GASPYPGVQI | NEEFCQRLKD | GTRMRAPELA | TPAIRHIMQS |
1200:
CWSGDPKARP | AFSDLVEILG | DLLQGGGWQE | EEEERMALHS | SQSSEEDGFM |
1250:
QASTTALHIT | EADADDSPPS | MHCHSLAARY | YNCVSFPGRL | ARGTKTPGSS |
1300:
RMKTFEELPM | TPTTYKASMD | NQTDSGMVLA | SEEFEELESR | HRPEGSFSCK |
1350:
GPGQHMDIPR | GHPDPQGRRR | RPTQGAQGGK | VFYNNEYGEV | SQPCTEGDCC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse VEGFR-3
ELISA Kit for Mouse VEGFR-3
ELISA Kit for Mouse VEGFR-3
CLIA Kit for Mouse VEGFR-3
CLIA Kit for Mouse VEGFR-3
CLIA Kit for Mouse VEGFR-3
Polyclonal Antibody for Mouse VEGFR-3
Polyclonal Antibody for Mouse VEGFR-3
Polyclonal Antibody for Mouse VEGFR-3
Monoclonal Antibody for Mouse VEGFR-3
Monoclonal Antibody for Mouse VEGFR-3
Monoclonal Antibody for Mouse VEGFR-3
Protein for Mouse VEGFR-3
Protein for Mouse VEGFR-3
Protein for Mouse VEGFR-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1033-1072
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-582
strain :
C57BL/6 .
tissue :
Plasma .
5.
"Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation."
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Cited for : FUNCTION;TISSUE SPECIFICITY
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN LYMPHANGIOGENESIS
7.
"Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN ACTIVATION OF SIGNALING PATHWAYS;SUBCELLULAR LOCATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN LYMPHANGIOGENESIS;ROLE IN CANCER
9.
"VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling."
Tammela T.
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Zarkada G.
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Nurmi H.
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,
Heinolainen K.
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Nat. Cell Biol.13:1202-1213(2011)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION