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Index > Protein center > Slc17a8(Gene name) > Rat
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  • Slc17a8 (Gene name),
  • Vesicular glutamate transporter 3 (Protein name ),  VGLU3_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc17a8(Vglut3);
    Protein name:
    Vesicular glutamate transporter 3(VGluT3);
    Alternative:
    Solute carrier family 17 member 8;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
    Subcellular Location:
    Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane Membrane Multi-pass membrane protein Cell junction synapse synaptosome
    Protein Attributes:
    Sequence length:
    588
    Sequence:
    50:
    MPFNAFDTFK | EKILKPGKEG | VKNAVGDSLG | ILQRKLDGTN | EEGDAIELSE | 
    100:
    EGRPVQTSRA | RAPVCDCSCC | GIPKRYIIAV | MSGLGFCISF | GIRCNLGVAI | 
    150:
    VEMVNNSTVY | VDGKPEIQTA | QFNWDPETVG | LIHGSFFWGY | IVTQIPGGFI | 
    200:
    SNKFAANRVF | GAAIFLTSTL | NMFIPSAARV | HYGCVMCVRI | LQGLVEGVTY | 
    250:
    PACHGMWSKW | APPLERSRLA | TTSFCGSYAG | AVVAMPLAGV | LVQYIGWASV | 
    300:
    FYIYGMFGII | WYMFWLLQAY | ECPAVHPTIS | NEERTYIETS | IGEGANLASL | 
    350:
    SKFNTPWRRF | FTSLPVYAII | VANFCRSWTF | YLLLISQPAY | FEEVFGFAIS | 
    400:
    KVGLLSAVPH | MVMTIVVPIG | GQLADYLRSR | KILTTTAVRK | IMNCGGFGME | 
    450:
    ATLLLVVGFS | HTKGVAISFL | VLAVGFSGFA | ISGFNVNHLD | IAPRYASILM | 
    500:
    GISNGVGTLS | GMVCPLIVGA | MTKHKTREEW | QNVFLIAALV | HYSGVIFYGV | 
    550:
    FASGEKQDWA | DPENLSEEKC | GIIDQDELAE | ETELNHEAFV | SPRKKMSYGA | 
    588:
    TTQNCEVQKT | DRRQQRESAF | EGEEPLSYQN | EEDFSETS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat VGluT3
    ELISA Kit for Rat VGluT3
    ELISA Kit for Rat VGluT3
    CLIA Kit for Rat VGluT3
    CLIA Kit for Rat VGluT3
    CLIA Kit for Rat VGluT3
    Polyclonal Antibody for Rat VGluT3
    Polyclonal Antibody for Rat VGluT3
    Polyclonal Antibody for Rat VGluT3
    Monoclonal Antibody for Rat VGluT3
    Monoclonal Antibody for Rat VGluT3
    Monoclonal Antibody for Rat VGluT3
    Protein for Rat VGluT3
    Protein for Rat VGluT3
    Protein for Rat VGluT3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons."
      Gras C. , Herzog E. , Bellenchi G.C. , Bernard V. , Ravassard P. , Pohl M. , Gasnier B. , Giros B. , El Mestikawy S.
      J. Neurosci.22:5442-5451(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Brain.
    2. 2.
      "The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate."
      Fremeau R.T. Jr. , Burman J. , Qureshi T. , Tran C.H. , Proctor J. , Johnson J. , Zhang H. , Sulzer D. , Copenhagen D.R. , Storm-Mathisen J. , Reimer R.J. , Chaudhry F.A. , Edwards R.H.
      Proc. Natl. Acad. Sci. U.S.A.99:14488-14493(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Liver.
    3. 3.
      "Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons."
      Schaefer M.K.-H. , Varoqui H. , Defamie N. , Weihe E. , Erickson J.D.
      J. Biol. Chem.277:50734-50748(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      "Localization of VGLUT3, the vesicular glutamate transporter type 3, in the rat brain."
      Herzog E. , Gilchrist J. , Gras C. , Muzerelle A. , Ravassard P. , Giros B. , Gaspar P. , El Mestikawy S.
      Neuroscience123:983-1002(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Inhibitory synapses in the developing auditory system are glutamatergic."
      Gillespie D.C. , Kim G. , Kandler K.
      Nat. Neurosci.8:332-338(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    8. 8.
      "Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3."
      Seal R.P. , Akil O. , Yi E. , Weber C.M. , Grant L. , Yoo J. , Clause A. , Kandler K. , Noebels J.L. , Glowatzki E. , Lustig L.R. , Edwards R.H.
      Neuron57:263-275(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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