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Index > Protein center > Ggcx(Gene name) > Rat
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  • Ggcx (Gene name),
  • Vitamin K-dependent gamma-carboxylase (Protein name ),  VKGC_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Ggcx;
    Protein name:
    Vitamin K-dependent gamma-carboxylase;
    Alternative:
    Peptidyl-glutamate 4-carboxylase;Gamma-glutamyl carboxylase;Vitamin K gamma glutamyl carboxylase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer (By similarity). Interacts with CALU.
    Function:
    Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    758
    Sequence:
    50:
    MAVHRGSARA | APASDKVQKN | KPAQTSGLEQ | GSRMARIFGF | EWADLSSWQS | 
    100:
    VVTLLNRPTD | PANLAVFRFL | FAFLMLLDIP | QERGLSSLDR | KYLDGLDVCR | 
    150:
    FPLLDALRPL | PLDWMYLVYT | IMFLGALGMM | LGLWYRLSCM | LFLLPYWYVF | 
    200:
    LLDKTSWNNH | SYLYGLLAFQ | LTFMDANHYW | SVDGLLSAQK | KNAHVPLWNY | 
    250:
    TVLRGQIFIV | YFIAGVKKLD | ADWVEGYSME | HLSRHWLFSP | FKLVLSEELT | 
    300:
    SLLVVHWCGL | LLDLSAGFLL | FFDASRPIGL | VFVSYFHCMN | SQLFSIGMFP | 
    350:
    YVMLASSPLF | CSAEWPRKLV | ARCPKRLQEL | LPAKAAPRPS | ASCVYKRARA | 
    400:
    KAGQKPGLRH | HLGTVFTLLY | LLEQLFLPYS | HFLTQGYNNW | TNGLYGYSWD | 
    450:
    MMVHSRSHQH | VKITYRDGLT | GELGYLNPGV | FTQSRRWKDH | ADMLKQYATC | 
    500:
    LSLLLPKYNV | TEPQIYFDIW | VSINDRFQQR | LFDPRVDIVQ | AVWSPFRRTP | 
    550:
    WVQPLLMDLS | PWRTKLQDIK | SSLDNHTEVV | FIADFPGLHL | ENFVSEDLGN | 
    600:
    TSIQLLQGEV | TVELVAEQKN | QTLREGEKMQ | LPAGEYHKVY | TVSSSPSCYM | 
    650:
    YIYVNTTEVA | LEQDLAYLQE | LKEKVENGSE | TGPLPPELQP | LLEGEVKGGP | 
    700:
    EPTPLVQTFL | RRQRKLQEIE | RRRNSPLHER | FLRFVLRKLY | VFRRSFLMTR | 
    750:
    ISLRNLLFGR | PSLEQLAQEV | TYANLRPFEP | VDESSASNTD | SSDPHPSEPD | 
    758:
    SEHVHSEL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Vitamin K-dependent gamma-carboxylase
    MSDS:
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    ELISA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    E15387h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    E15387b
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    Packing:
    96T
    ELISA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    E15387m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    U15387b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    U15387m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    U15387r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    U15387h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    P15387Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    P15387Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Cat.:
    P15387Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Monoclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Monoclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Monoclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Monoclonal Antibody for Rat Vitamin K-dependent gamma-carboxylase
    Protein for Rat Vitamin K-dependent gamma-carboxylase
    Protein for Rat Vitamin K-dependent gamma-carboxylase
    Protein for Rat Vitamin K-dependent gamma-carboxylase
    Protein for Rat Vitamin K-dependent gamma-carboxylase

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning, structural organization, and transcriptional activity of the rat vitamin K-dependent gamma-glutamyl carboxylase gene."
      Romero E.E. , Deo R. , Velazquez-Estades L.J. , Roth D.A.
      Biochem. Biophys. Res. Commun.248:783-788(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "Cloning of rat vitamin K-dependent gamma-glutamyl carboxylase and developmentally regulated gene expression in post-implantation embryos."
      Romero E.E. , Velazquez-Estades L.J. , Deo R. , Schapiro B. , Roth D.A.
      Exp. Cell Res.243:334-346(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    3. 3.
      "The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats."
      Wajih N. , Sane D.C. , Hutson S.M. , Wallin R.
      J. Biol. Chem.279:25276-25283(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CALU
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