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Index > Protein center > VNN2(Gene name) > Human
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  • VNN2 (Gene name),
  • Vascular non-inflammatory molecule 2 (Protein name ),  VNN2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VNN2;
    Protein name:
    Vascular non-inflammatory molecule 2(Vanin-2);
    Alternative:
    Protein FOAP-4;Glycosylphosphatidyl inositol-anchored protein GPI-80;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    520
    Sequence:
    50:
    MVTSSFPISV | AVFALITLQV | GTQDSFIAAV | YEHAVILPNK | TETPVSQEDA | 
    100:
    LNLMNENIDI | LETAIKQAAE | QGARIIVTPE | DALYGWKFTR | ETVFPYLEDI | 
    150:
    PDPQVNWIPC | QDPHRFGHTP | VQARLSCLAK | DNSIYVLANL | GDKKPCNSRD | 
    200:
    STCPPNGYFQ | YNTNVVYNTE | GKLVARYHKY | HLYSEPQFNV | PEKPELVTFN | 
    250:
    TAFGRFGIFT | CFDIFFYDPG | VTLVKDFHVD | TILFPTAWMN | VLPLLTAIEF | 
    300:
    HSAWAMGMGV | NLLVANTHHV | SLNMTGSGIY | APNGPKVYHY | DMKTELGKLL | 
    350:
    LSEVDSHPLS | SLAYPTAVNW | NAYATTIKPF | PVQKNTFRGF | ISRDGFNFTE | 
    400:
    LFENAGNLTV | CQKELCCHLS | YRMLQKEENE | VYVLGAFTGL | HGRRRREYWQ | 
    450:
    VCTLLKCKTT | NLTTCGRPVE | TASTRFEMFS | LSGTFGTEYV | FPEVLLTEIH | 
    500:
    LSPGKFEVLK | DGRLVNKNGS | SGPILTVSLF | GRWYTKDSLY | SSCGTSNSAI | 
    520:
    TYLLIFILLM | IIALQNIVML | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    String:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Vanin-2
    CLIA Kit for Human Vanin-2
    Polyclonal Antibody for Human Vanin-2
    Monoclonal Antibody for Human Vanin-2
    Protein for Human Vanin-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6."
      Galland F. , Malergue F. , Bazin H. , Mattei M.-G. , Aurrand-Lions M. , Theillet C. , Naquet P.
      Genomics53:203-213(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-404
      tissue: Kidney.
    2. 2.
      "A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: a possible role for regulation of neutrophil adherence and migration."
      Suzuki K. , Watanabe T. , Sakurai S. , Ohtake K. , Kinoshita T. , Araki A. , Fujita T. , Takei H. , Takeda Y. , Sato Y. , Yamashita T. , Araki Y. , Sendo F.
      J. Immunol.162:4277-4284(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-404
      tissue: Peripheral blood.
    3. 3.
      "Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils."
      Nitto T. , Inoue T. , Node K.
      Gene426:57-64(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);VARIANT MET-404
      tissue: Neutrophil.
    4. 4.
      "Homo sapiens mRNA for FOAP-4 protein, complete cds."
      Takayama K. , Fujii Y. , Tsuritani K. , Yajima Y. , Amemiya T. , Ukai Y. , Naito K. , Kawaguchi A.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-404
      tissue: Blood.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 6);VARIANT MET-404
      tissue: Synovium.
    6. 6.
      NIEHS SNPs program
      Submitted (2005-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ASN-17; GLU-112; ILE-241; SER-349 AND MET-404
    7. 7.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT MET-404
    10. 10.
      "Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes."
      Martin F. , Malergue F. , Pitari G. , Philippe J.M. , Philips S. , Chabret C. , Granjeaud S. , Mattei M.G. , Mungall A.J. , Naquet P. , Galland F.
      Immunogenetics53:296-306(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    11. 11.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-411
      tissue: Plasma.
    12. 12.
      "Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines."
      Jansen P.A.M. , Kamsteeg M. , Rodijk-Olthuis D. , van Vlijmen-Willems I.M.J.J. , de Jongh G.J. , Bergers M. , Tjabringa G.S. , Zeeuwen P.L.J.M. , Schalkwijk J.
      J. Invest. Dermatol.129:2167-2174(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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