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Index > Protein center > Vps26a(Gene name) > Mouse
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  • Vps26a (Gene name),
  • Vacuolar protein sorting-associated protein 26A (Protein name ),  VP26A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Vps26a(Vps26);
    Protein name:
    Vacuolar protein sorting-associated protein 26A;
    Alternative:
    Vesicle protein sorting 26A(mVPS26);H58 protein(H beta 58);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN (By similarity). Interacts with ECM29.
    Function:
    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
    Subcellular Location:
    Cytoplasm Endosome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    327
    Sequence:
    50:
    MSFLGGFFGP | ICEIDVALND | GETRKMAEMK | TEDGKVEKHY | LFYDGESVSG | 
    100:
    KVNLAFKQPG | KRLEHQGIRI | EFVGQIELFN | DKSNTHEFVN | LVKELALPGE | 
    150:
    LTQSRSYDFE | FMQVEKPYES | YIGANVRLRY | FLKVTIVRRL | TDLVKEYDLI | 
    200:
    VHQLATYPDV | NNSIKMEVGI | EDCLHIEFEY | NKSKYHLKDV | IVGKIYFLLV | 
    250:
    RIKIQHMELQ | LIKKEITGIG | PSTTTETETI | AKYEIMDGAP | VKGESIPIRL | 
    300:
    FLAGYDPTPT | MRDVNKKFSV | RYFLNLVLVD | EEDRRYFKQQ | EIILWRKAPE | 
    327:
    KLRKQRTNFH | QRFESPDSQA | SAEQPEM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    ELISA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    ELISA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    ELISA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    CLIA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    CLIA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    CLIA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    CLIA Kit for Mouse Vacuolar protein sorting-associated protein 26A
    Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 26A
    Protein for Mouse Vacuolar protein sorting-associated protein 26A
    Protein for Mouse Vacuolar protein sorting-associated protein 26A
    Protein for Mouse Vacuolar protein sorting-associated protein 26A
    Protein for Mouse Vacuolar protein sorting-associated protein 26A

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine H beta 58 embryonic lethal transgene insertion."
      Lee J.J. , Radice G. , Perkins C.P. , Costantini F.
      Development115:277-288(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      strain: DBA/2.
      tissue: Amnion.
      tissue: Bone marrow.
      tissue: Lung.
      tissue: Placenta.
      tissue: Testis.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Mammary tumor.
    4. 4.
      "Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer."
      Seaman M.N.J.
      J. Cell Biol.165:111-122(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    5. 5.
      "Structure of Vps26B and mapping of its interaction with the retromer protein complex."
      Collins B.M. , Norwood S.J. , Kerr M.C. , Mahony D. , Seaman M.N. , Teasdale R.D. , Owen D.J.
      Traffic9:366-379(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;MUTAGENESIS OF 235-ILE-MET-236;SUBCELLULAR LOCATION
    6. 6.
      "Assembly and solution structure of the core retromer protein complex."
      Norwood S.J. , Shaw D.J. , Cowieson N.P. , Owen D.J. , Teasdale R.D. , Collins B.M.
      Traffic12:56-71(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    7. 7.
      "Vps26A and Vps26B subunits define distinct retromer complexes."
      Bugarcic A. , Zhe Y. , Kerr M.C. , Griffin J. , Collins B.M. , Teasdale R.D.
      Traffic12:1759-1773(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    8. 8.
      "A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer."
      Gallon M. , Clairfeuille T. , Steinberg F. , Mas C. , Ghai R. , Sessions R.B. , Teasdale R.D. , Collins B.M. , Cullen P.J.
      Proc. Natl. Acad. Sci. U.S.A.111:E3604-E3613(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 9-327;FUNCTION;INTERACTION WITH SNX27;MUTAGENESIS OF ASP-44 AND LEU-154
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