Gene name:
VPS37D (WBSCR24) ;
Protein name:
Vacuolar protein sorting-associated protein 37D ;
Alternative:
Williams-Beuren syndrome chromosomal region 24 protein ;ESCRT-I complex subunit VPS37D ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and a FAM125/MVB12 protein (FAM125A or -B) in a 1:1:1:1 stoechiometry. Interacts with TSG101 and FAM125A.
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular Location:
Late endosome membrane
Peripheral membrane protein
Protein Attributes:
50:
MYRARAARAG | PEPGSPGRFG | ILSTGQLRDL | LQDEPKLDRI | VRLSRKFQGL |
100:
QLEREACLAS | NYALAKENLA | LRPRLEMGRA | ALAIKYQELR | EVAENCADKL |
150:
QRLEESMHRW | SPHCALGWLQ | AELEEAEQEA | EEQMEQLLLG | EQSLEAFLPA |
200:
FQRGRALAHL | RRTQAEKLQE | LLRRRERSAQ | PAPTSAADPP | KSFPAAAVLP |
250:
TGAARGPPAV | PRSLPPLDSR | PVPPLKGSPG | CPLGPAPLLS | PRPSQPEPPH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Vacuolar protein sorting-associated protein 37D
ELISA Kit for Human Vacuolar protein sorting-associated protein 37D
CLIA Kit for Human Vacuolar protein sorting-associated protein 37D
CLIA Kit for Human Vacuolar protein sorting-associated protein 37D
Polyclonal Antibody for Human Vacuolar protein sorting-associated protein 37D
Polyclonal Antibody for Human Vacuolar protein sorting-associated protein 37D
Monoclonal Antibody for Human Vacuolar protein sorting-associated protein 37D
Monoclonal Antibody for Human Vacuolar protein sorting-associated protein 37D
Protein for Human Vacuolar protein sorting-associated protein 37D
Protein for Human Vacuolar protein sorting-associated protein 37D
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Novel genes in the Williams-Beuren Syndrome critical region."
Ucla C.
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Reymond A.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"The DNA sequence of human chromosome 7."
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more...
Nature424:157-164(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-251
tissue :
Ovary .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TSG101 AND MVB12A;IDENTIFICATION BY MASS SPECTROMETRY
6.
"The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain."
Agromayor M.
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Structure20:414-428(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN AN ESCRT-I COMPLEX WITH UBAP1;SUBUNIT