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Index > Protein center > VPS45(Gene name) > Human
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  • VPS45 (Gene name),
  • Vacuolar protein sorting-associated protein 45 (Protein name ),  VPS45_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VPS45(VPS45A;VPS45B);
    Protein name:
    Vacuolar protein sorting-associated protein 45(h-VPS45;hlVps45);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with STX6 (By similarity). Interacts with ZFYVE20.
    Function:
    May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
    Subcellular Location:
    Golgi apparatus membrane Peripheral membrane protein Endosome membrane Peripheral membrane protein Associated with Golgi/endosomal vesicles and the trans-Golgi network.
    Protein Attributes:
    Sequence length:
    570
    Sequence:
    50:
    MNVVFAVKQY | ISKMIEDSGP | GMKVLLMDKE | TTGIVSMVYT | QSEILQKEVY | 
    100:
    LFERIDSQNR | EIMKHLKAIC | FLRPTKENVD | YIIQELRRPK | YTIYFIYFSN | 
    150:
    VISKSDVKSL | AEADEQEVVA | EVQEFYGDYI | AVNPHLFSLN | ILGCCQGRNW | 
    200:
    DPAQLSRTTQ | GLTALLLSLK | KCPMIRYQLS | SEAAKRLAEC | VKQVITKEYE | 
    250:
    LFEFRRTEVP | PLLLILDRCD | DAITPLLNQW | TYQAMVHELL | GINNNRIDLS | 
    300:
    RVPGISKDLR | EVVLSAENDE | FYANNMYLNF | AEIGSNIKNL | MEDFQKKKPK | 
    350:
    EQQKLESIAD | MKAFVENYPQ | FKKMSGTVSK | HVTVVGELSR | LVSERNLLEV | 
    400:
    SEVEQELACQ | NDHSSALQNI | KRLLQNPKVT | EFDAARLVML | YALHYERHSS | 
    450:
    NSLPGLMMDL | RNKGVSEKYR | KLVSAVVEYG | GKRVRGSDLF | SPKDAVAITK | 
    500:
    QFLKGLKGVE | NVYTQHQPFL | HETLDHLIKG | RLKENLYPYL | GPSTLRDRPQ | 
    550:
    DIIVFVIGGA | TYEEALTVYN | LNRTTPGVRI | VLGGTTVHNT | KSFLEEVLAS | 
    570:
    GLHSRSKESS | QVTSRSASRR | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human h-VPS45
    ELISA Kit for Human h-VPS45
    ELISA Kit for Human h-VPS45
    CLIA Kit for Human h-VPS45
    CLIA Kit for Human h-VPS45
    CLIA Kit for Human h-VPS45
    Polyclonal Antibody for Human h-VPS45
    Polyclonal Antibody for Human h-VPS45
    Polyclonal Antibody for Human h-VPS45
    Monoclonal Antibody for Human h-VPS45
    Monoclonal Antibody for Human h-VPS45
    Monoclonal Antibody for Human h-VPS45
    Protein for Human h-VPS45
    Protein for Human h-VPS45
    Protein for Human h-VPS45

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking."
      Pevsner J. , Hsu S.-C. , Hyde P.S. , Scheller R.H.
      Gene183:7-14(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    2. 2.
      "Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (hlVps45)."
      Rajasekariah P. , Eyre H.J. , Stanley K.K. , Walls R.S. , Sutherland G.R.
      Int. J. Biochem. Cell Biol.31:683-694(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Leukocyte.
    3. 3.
      "Novel genes expressed in hematopoietic stem/progenitor cells from myelodysplastic syndrome patients."
      Gu J. , Huang Q. , Yu Y. , Xu S. , Han Z. , Fu G. , Zhou J. , Wang Y. , Huang C. , Ren S. , Tu Y. , Chen Z.
      Submitted (1999-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Hematopoietic stem cell.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Gastric mucosa.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
      tissue: Hippocampus.
    9. 9.
      "Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain."
      Nielsen E. , Christoforidis S. , Uttenweiler-Joseph S. , Miaczynska M. , Dewitte F. , Wilm M. , Hoflack B. , Zerial M.
      J. Cell Biol.151:601-612(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZFYVE20
    10. 10.
      "Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes."
      de Renzis S. , Soennichsen B. , Zerial M.
      Nat. Cell Biol.4:124-133(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZFYVE20
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SCN5 ASN-224 AND LYS-238
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