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Index > Protein center > VWCE(Gene name) > Human
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  • VWCE (Gene name),
  • von Willebrand factor C and EGF domain-containing protein (Protein name ),  VWCE_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VWCE(URG11);
    Protein name:
    von Willebrand factor C and EGF domain-containing protein;
    Alternative:
    HBxAg up-regulated gene 11 protein;HBV X protein up-regulated gene 11 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma.
    Subcellular Location:
    Secreted According to PubMed:16496348 is localized in the cytoplasm.
    Protein Attributes:
    Sequence length:
    955
    Sequence:
    50:
    MWAGLLLRAA | CVALLLPGAP | ARGYTGRKPP | GHFAAERRRL | GPHVCLSGFG | 
    100:
    SGCCPGWAPS | MGGGHCTLPL | CSFGCGSGIC | IAPNVCSCQD | GEQGATCPET | 
    150:
    HGPCGEYGCD | LTCNHGGCQE | VARVCPVGFS | MTETAVGIRC | TDIDECVTSS | 
    200:
    CEGHCVNTEG | GFVCECGPGM | QLSADRHSCQ | DTDECLGTPC | QQRCKNSIGS | 
    250:
    YKCSCRTGFH | LHGNRHSCVD | VNECRRPLER | RVCHHSCHNT | VGSFLCTCRP | 
    300:
    GFRLRADRVS | CEAFPKAVLA | PSAILQPRQH | PSKMLLLLPE | AGRPALSPGH | 
    350:
    SPPSGAPGPP | AGVRTTRLPS | PTPRLPTSSP | SAPVWLLSTL | LATPVPTASL | 
    400:
    LGNLRPPSLL | QGEVMGTPSS | PRGPESPRLA | AGPSPCWHLG | AMHESRSRWT | 
    450:
    EPGCSQCWCE | DGKVTCEKVR | CEAACSHPIP | SRDGGCCPSC | TGCFHSGVVR | 
    500:
    AEGDVFSPPN | ENCTVCVCLA | GNVSCISPEC | PSGPCQTPPQ | TDCCTCVPVR | 
    550:
    CYFHGRWYAD | GAVFSGGGDE | CTTCVCQNGE | VECSFMPCPE | LACPREEWRL | 
    600:
    GPGQCCFTCQ | EPTPSTGCSL | DDNGVEFPIG | QIWSPGDPCE | LCICQADGSV | 
    650:
    SCKRTDCVDS | CPHPIRIPGQ | CCPDCSAGCT | YTGRIFYNNE | TFPSVLDPCL | 
    700:
    SCICLLGSVA | CSPVDCPITC | TYPFHPDGEC | CPVCRDCNYE | GRKVANGQVF | 
    750:
    TLDDEPCTRC | TCQLGEVSCE | KVPCQRACAD | PALLPGDCCS | SCPDSLSPLE | 
    800:
    EKQGLSPHGN | VAFSKAGRSL | HGDTEAPVNC | SSCPGPPTAS | PSRPVLHLLQ | 
    850:
    LLLRTNLMKT | QTLPTSPAGA | HGPHSLALGL | TATFPGEPGA | SPRLSPGPST | 
    900:
    PPGAPTLPLA | SPGAPQPPPV | TPERSFSASG | AQIVSRWPPL | PGTLLTEASA | 
    950:
    LSMMDPSPSK | TPITLLGPRV | LSPTTSRLST | ALAATTHPGP | QQPPVGASRG | 
    955:
    EESTM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human von Willebrand factor C and EGF domain-containing protein
    ELISA Kit for Human von Willebrand factor C and EGF domain-containing protein
    CLIA Kit for Human von Willebrand factor C and EGF domain-containing protein
    CLIA Kit for Human von Willebrand factor C and EGF domain-containing protein
    Polyclonal Antibody for Human von Willebrand factor C and EGF domain-containing protein
    Polyclonal Antibody for Human von Willebrand factor C and EGF domain-containing protein
    Monoclonal Antibody for Human von Willebrand factor C and EGF domain-containing protein
    Monoclonal Antibody for Human von Willebrand factor C and EGF domain-containing protein
    Protein for Human von Willebrand factor C and EGF domain-containing protein
    Protein for Human von Willebrand factor C and EGF domain-containing protein

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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Teratocarcinoma.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Lymph.
    4. 4.
      "Upregulated expression of a unique gene by hepatitis B x antigen promotes hepatocellular growth and tumorigenesis."
      Lian Z. , Liu J. , Li L. , Li X. , Tufan S.N.L. , Clayton M. , Wu M.-C. , Wang H.-Y. , Arbuthnot P. , Kew M. , Feitelson M.A.
      Neoplasia5:229-244(2003)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 73-955 (ISOFORM 1)
    5. 5.
      "Enhanced cell survival of Hep3B cells by the hepatitis B x antigen effector, URG11, is associated with upregulation of beta-catenin."
      Lian Z. , Liu J. , Li L. , Li X. , Clayton M. , Wu M.-C. , Wang H.-Y. , Arbuthnot P. , Kew M. , Fan D. , Feitelson M.A.
      Hepatology43:415-424(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION BY HBXAG;TISSUE SPECIFICITY
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