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Index > Protein center > Wac(Gene name) > Mouse
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  • Wac (Gene name),
  • WW domain-containing adapter protein with coiled-coil (Protein name ),  WAC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Wac(Kiaa1844);
    Protein name:
    WW domain-containing adapter protein with coiled-coil;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts (via coiled coil domain) with RNF20, RNF40 and UBE2A. Interacts (via WW domain) with RNA polymerase II.
    Function:
    Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage.
    Subcellular Location:
    Nucleus speckle Nucleus In distinct nuclear speckles. Colocalizes with pre-mRNA processing complexes.
    Protein Attributes:
    Sequence length:
    646
    Sequence:
    50:
    MVMYARKQQR | LSDGCHDRRG | DSQPFQALKY | SSKSHPSSGD | HRHEKMRDAA | 
    100:
    DPSPPNKMLR | RSNSPENKYS | DSTGHNKAKN | VHTQRVRERD | GGTSYSPQEN | 
    150:
    SHNHSALHSS | NSHSSNPSNN | PSKTSDAPYD | SADDWSEHIS | SSGKKYYYNC | 
    200:
    RTEVSQWEKP | KEWLEREQRQ | KEANKLAVNS | FPKDRDYRRE | VMQATATSGF | 
    250:
    TSGMEDKHSS | DASSLLPQNI | LSQTSRHNDK | DYRLPRAETH | SSSTPVQHPI | 
    300:
    KPVVHPTATP | STVPSSPFTL | QSDHQPKKSF | DANGASTLSK | LPTPTASLPA | 
    350:
    QKTERKESAP | GDKSISHSCT | TPSTSSASGL | NPTSAPPTSA | SAVPVSPVPQ | 
    400:
    STIPPLLQDP | NLFRQLLPAL | QATLQLNNSN | VDISKINEVL | TAAVTQASLQ | 
    450:
    SIIHKFLTAG | PSAFNITSLI | SQAAQLSTQA | QPSNQSPMSL | TSDASSPRSY | 
    500:
    VSPRISTPQT | NTVPMKPLIS | TPPVSSQPKV | STPVVKQGPV | SHSATQQPVT | 
    550:
    ADKQQSHDPV | SPRSLQRLSS | QRSPSPGPNH | TCSSNASTAT | VVPQNASARP | 
    600:
    ACSLTPTLAA | HFNDNLIKHV | QGWPADHAEK | QASRLREEAH | NMGSVHMSEI | 
    646:
    CTELKNLRSL | VRVCEIQATL | REQRILFLRQ | QIKELEKLKN | QNSFMV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse WW domain-containing adapter protein with coiled-coil
    ELISA Kit for Mouse WW domain-containing adapter protein with coiled-coil
    CLIA Kit for Mouse WW domain-containing adapter protein with coiled-coil
    CLIA Kit for Mouse WW domain-containing adapter protein with coiled-coil
    Polyclonal Antibody for Mouse WW domain-containing adapter protein with coiled-coil
    Polyclonal Antibody for Mouse WW domain-containing adapter protein with coiled-coil
    Monoclonal Antibody for Mouse WW domain-containing adapter protein with coiled-coil
    Monoclonal Antibody for Mouse WW domain-containing adapter protein with coiled-coil
    Protein for Mouse WW domain-containing adapter protein with coiled-coil
    Protein for Mouse WW domain-containing adapter protein with coiled-coil

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "WAC, a novel WW domain-containing adapter with a coiled-coil region, is colocalized with splicing factor SC35."
      Xu G.M. , Arnaout M.A.
      Genomics79:87-94(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PHOSPHORYLATION;SUBCELLULAR LOCATION
      strain: C57BL/6.
    2. 2.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
      DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Pancreatic islet.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Ovary.
      tissue: Retina.
      tissue: Spleen.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Brain.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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