Wasf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comWasf1 ELISA Kit for Rat(Rattus norvegicus)

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Wasf1 (Gene name),

Wiskott-Aldrich syndrome protein family member 1 (Protein name ), WASF1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Wasf1(Wave1);

Protein name:

Wiskott-Aldrich syndrome protein family member 1(WASP family protein member 1);

Alternative:

Protein WAVE-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the WAVE1 complex composed of ABI2, CYFIP1 or CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Within the complex, a heterdimer containing NCKAP1 and CYFIP1 interacts with a heterotrimer formed by WAVE1, ABI2 and BRK1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1. Binds actin and the Arp2/3 complex. Interacts with BAIAP2.

Function:

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Subcellular Location:

Cytoplasm cytoskeleton Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas.

Protein Attributes:

Sequence length:

559

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

559:

EFDEVDWLE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF02205

KEGG:

rno:294568

UniGene:

Rn.7692

Uniprot:

Q5BJU7

FOR

ELISA Kit for Rat WASP family protein member 1

CLIA Kit for Rat WASP family protein member 1

Polyclonal Antibody for Rat WASP family protein member 1

Monoclonal Antibody for Rat WASP family protein member 1

Protein for Rat WASP family protein member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
2.

"Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation."
Proepper C. , Johannsen S. , Liebau S. , Dahl J. , Vaida B. , Bockmann J. , Kreutz M.R. , Gundelfinger E.D. , Boeckers T.M.
EMBO J.26:1397-1409(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ABI1;TISSUE SPECIFICITY;SUBCELLULAR LOCATION

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