Protein name:
Wiskott-Aldrich syndrome protein family member 2 (WASP family protein member 2) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with BRK1.
Function:
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
Subcellular Location:
Cytoplasm
cytoskeleton
Cell projection
lamellipodium
At the interface between the lamellipodial actin meshwork and the membrane.
Protein Attributes:
50:
MPLVTRNIEP | RHLCRQTLPS | VRSELECMTN | ITLANVIRQL | GSLSKYAEDI |
100:
FGELFTQANT | FASRVSSLAE | RVDRLQVKVT | QLDPKEEEVS | LQGINTRKAF |
150:
RSSTVQDQKL | FDRNSLPIPV | LETYNTCDTP | PPLNNLTPYR | DDGKEALKFY |
200:
TDPSYFFDLW | KEKMLQDTKD | IMKEKRKHRK | EKKDNPNRGN | VNPRKIKTRK |
250:
EEWEKMKMGQ | EFVESKEKPS | RYPPTLVYQN | GSIGSVENVD | AGNYPPPPQS |
300:
DSISPPSPSF | SEDNLPPPPA | EFSYPADNNQ | RAGLKRSSVV | SPSHPPPAPP |
350:
LGSAPGPKPG | FAPPPAPPPP | PPMINTPPPP | PPGGFGSPAT | PPPPSPPSFP |
400:
PHPDFAAPPP | PPPPPAVDYS | TLPPPPLSQS | AGGAPPPPPP | PPPPGPPPPP |
450:
FSGADGQLAA | PPPPLSDTTK | PKSSLPPVSD | ARSDLLSAIR | QGFQLRRVEE |
493:
QREQEKRDVV | GNDVATILSR | RIAVEYSDSE | DDSSEFDEDE | WSD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Bovine WASP family protein member 2
ELISA Kit for Bovine WASP family protein member 2
ELISA Kit for Bovine WASP family protein member 2
CLIA Kit for Bovine WASP family protein member 2
CLIA Kit for Bovine WASP family protein member 2
CLIA Kit for Bovine WASP family protein member 2
Polyclonal Antibody for Bovine WASP family protein member 2
Polyclonal Antibody for Bovine WASP family protein member 2
Polyclonal Antibody for Bovine WASP family protein member 2
Monoclonal Antibody for Bovine WASP family protein member 2
Monoclonal Antibody for Bovine WASP family protein member 2
Monoclonal Antibody for Bovine WASP family protein member 2
Protein for Bovine WASP family protein member 2
Protein for Bovine WASP family protein member 2
Protein for Bovine WASP family protein member 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal pons .