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Index > Protein center > Wasf2(Gene name) > Mouse
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  • Wasf2 (Gene name),
  • Wiskott-Aldrich syndrome protein family member 2 (Protein name ),  WASF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Wasf2(Wave2);
    Protein name:
    Wiskott-Aldrich syndrome protein family member 2(WASP family protein member 2);
    Alternative:
    Protein WAVE-2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with BRK1.
    Function:
    Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    497
    Sequence:
    50:
    MPLVTRNIEP | RHLCRQTLPS | DTSELECRTN | ITLANVIRQL | GSLSKYAEDI | 
    100:
    FGEICTQASA | FASRVNSLAE | RVDRVQVKVT | QLDPKEEEVS | LQGINTRKAF | 
    150:
    RSSTTQDQKL | FDRNSLPVPV | LETYNSCDAP | PPLNNLSPYR | DDGKEALKFY | 
    200:
    TNPSYFFDLW | KEKMLQDTKD | IMKEKRKHRK | EKKDNPNRGN | VNPRKIKTRK | 
    250:
    EEWEKMKMGQ | EFVESKERLG | PSGYSSTLVY | QNGSIGSVEN | VDAASYPPPP | 
    300:
    QSDSASSPSP | SFSEDNLPPP | PAEFSYPADN | QRGSVLAGPK | RTSMVSPSHP | 
    350:
    PPAPPLSSPP | GPKPGFAPPP | APPPPPPMSV | PPPLPSMGFG | SPGTPPPPSP | 
    400:
    PSFPPHPDFA | APPPPPPPPA | ADYPMPPPPL | SQPSGGAPPP | PPPPPPPGPP | 
    450:
    PLPFSGADGQ | PAAPPPPPPS | EATKPKSSLP | AVSDARSDLL | SAIRQGFQLR | 
    497:
    RVEEQREQEK | RDVVGNDVAT | ILSRRIAVEY | SDSEDDSSEF | DEDDWSD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse WASP family protein member 2
    ELISA Kit for Mouse WASP family protein member 2
    ELISA Kit for Mouse WASP family protein member 2
    CLIA Kit for Mouse WASP family protein member 2
    CLIA Kit for Mouse WASP family protein member 2
    CLIA Kit for Mouse WASP family protein member 2
    Polyclonal Antibody for Mouse WASP family protein member 2
    Polyclonal Antibody for Mouse WASP family protein member 2
    Polyclonal Antibody for Mouse WASP family protein member 2
    Monoclonal Antibody for Mouse WASP family protein member 2
    Monoclonal Antibody for Mouse WASP family protein member 2
    Monoclonal Antibody for Mouse WASP family protein member 2
    Protein for Mouse WASP family protein member 2
    Protein for Mouse WASP family protein member 2
    Protein for Mouse WASP family protein member 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genomic organization and expression profile of the human and mouse WAVE gene family."
      Sossey-Alaoui K. , Head K. , Nowak N. , Cowell J.K.
      Mamm. Genome14:314-322(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
    3. 3.
      "Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation."
      Steffen A. , Rottner K. , Ehinger J. , Innocenti M. , Scita G. , Wehland J. , Stradal T.E.B.
      EMBO J.23:749-759(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPONENT OF WAVE2 COMPLEX
      strain: C57BL/6.
      tissue: Brain.
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