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Index > Protein center > WASF3(Gene name) > Human
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  • WASF3 (Gene name),
  • Wiskott-Aldrich syndrome protein family member 3 (Protein name ),  WASF3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    WASF3(KIAA0900;SCAR3;WAVE3);
    Protein name:
    Wiskott-Aldrich syndrome protein family member 3(WASP family protein member 3);
    Alternative:
    Verprolin homology domain-containing protein 3;Protein WAVE-3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds actin and the Arp2/3 complex.
    Function:
    Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    502
    Sequence:
    50:
    MPLVKRNIEP | RHLCRGALPE | GITSELECVT | NSTLAAIIRQ | LSSLSKHAED | 
    100:
    IFGELFNEAN | NFYIRANSLQ | DRIDRLAVKV | TQLDSTVEEV | SLQDINMKKA | 
    150:
    FKSSTVQDQQ | VVSKNSIPNP | VADIYNQSDK | PPPLNILTPY | RDDKKDGLKF | 
    200:
    YTDPSYFFDL | WKEKMLQDTE | DKRKEKRRQK | EQKRIDGTTR | EVKKVRKARN | 
    250:
    RRQEWNMMAY | DKELRPDNRL | SQSVYHGASS | EGSLSPDTRS | HASDVTDYSY | 
    300:
    PATPNHSLHP | QPVTPSYAAG | DVPPHGPASQ | AAEHEYRPPS | ASARHMALNR | 
    350:
    PQQPPPPPPP | QAPEGSQASA | PMAPADYGML | PAQIIEYYNP | SGPPPPPPPP | 
    400:
    VIPSAQTAFV | SPLQMPMQPP | FPASASSTHA | APPHPPSTGL | LVTAPPPPGP | 
    450:
    PPPPPGPPGP | GSSLSSSPMH | GPPVAEAKRQ | EPAQPPISDA | RSDLLAAIRM | 
    500:
    GIQLKKVQEQ | REQEAKREPV | GNDVATILSR | RIAVEYSDSD | DDSEFDENDW | 
    502:
    SD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    KEGG:
    UniGene:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human WASP family protein member 3
    ELISA Kit for Human WASP family protein member 3
    CLIA Kit for Human WASP family protein member 3
    CLIA Kit for Human WASP family protein member 3
    Polyclonal Antibody for Human WASP family protein member 3
    Polyclonal Antibody for Human WASP family protein member 3
    Monoclonal Antibody for Human WASP family protein member 3
    Monoclonal Antibody for Human WASP family protein member 3
    Protein for Human WASP family protein member 3
    Protein for Human WASP family protein member 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex."
      Suetsugu S. , Miki H. , Takenawa T.
      Biochem. Biophys. Res. Commun.260:296-302(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    2. 2.
      "Genomic organization and expression profile of the human and mouse WAVE gene family."
      Sossey-Alaoui K. , Head K. , Nowak N. , Cowell J.K.
      Mamm. Genome14:314-322(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    5. 5.
      "The DNA sequence and analysis of human chromosome 13."
      Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
      Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    8. 8.
      Machesky L.M. , Insall R.H.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 48-502 (ISOFORM 1)
    9. 9.
      "c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration."
      Sossey-Alaoui K. , Li X. , Cowell J.K.
      J. Biol. Chem.282:26257-26265(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT TYR-151; TYR-248; TYR-337 AND TYR-486
    10. 10.
      "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."
      Bai S.W. , Herrera-Abreu M.T. , Rohn J.L. , Racine V. , Tajadura V. , Suryavanshi N. , Bechtel S. , Wiemann S. , Baum B. , Ridley A.J.
      BMC Biol.9:54-54(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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