Wasl ELISA Kit for Rat(Rattus norvegicus) | EIAab.comWasl ELISA Kit for Rat(Rattus norvegicus)

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Wasl (Gene name),

Neural Wiskott-Aldrich syndrome protein (Protein name ), WASL_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Wasl;

Protein name:

Neural Wiskott-Aldrich syndrome protein(N-WASP);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds actin and the Arp2/3 complex. Interacts with CDC42. Binds to SH3 domains of GRB2. Interacts with the C-terminal SH3 domain of DNMBP. Interacts with the WW domains of PRPF40A/FBP11. Interacts with NOSTRIN and SNX9.

Function:

Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.

Subcellular Location:

Cytoplasm cytoskeleton Nucleus Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated.

Protein Attributes:

Sequence length:

501

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

501:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.126640

UniGene:

Rn.216426

Pfam:

PF00786

String:

O08816

SMR:

O08816

STRING:

10116.ENSRNOP00000009261

Uniprot:

O08816

FOR

ELISA Kit for Rat N-WASP

CLIA Kit for Rat N-WASP

Polyclonal Antibody for Rat N-WASP

Monoclonal Antibody for Rat N-WASP

Protein for Rat N-WASP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of N-WASP homologs in human and rat brain."
Fukuoka M. , Miki H. , Takenawa T.
Gene196:43-48(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Focal adhesion kinase regulation of N-WASP subcellular localization and function."
Wu X. , Suetsugu S. , Cooper L.A. , Takenawa T. , Guan J.L.
J. Biol. Chem.279:9565-9576(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTK2/FAK1;SUBCELLULAR LOCATION;PHOSPHORYLATION AT TYR-253
3.

"Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome."
Volkman B.F. , Prehoda K.E. , Scott J.A. , Peterson F.C. , Lim W.A.
Cell111:565-576(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 37-485

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