WDFY3 ELISA Kit for Human(Homo sapiens) | EIAab.comWDFY3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > WDFY3(Gene name) > Human

WDFY3 (Gene name),

WD repeat and FYVE domain-containing protein 3 (Protein name ), WDFY3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WDFY3(KIAA0993);

Protein name:

WD repeat and FYVE domain-containing protein 3;

Alternative:

Autophagy-linked FYVE protein(Alfy);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

N/A

Subcellular Location:

Membrane Peripheral membrane protein Cytoplasmic side Co-localizes with autophagic structures in starved cells.

Protein Attributes:

Sequence length:

3526

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SPVRVCQNCY | YNLQHERGSE | DGPRNC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8IZQ1

Pfam:

PF02138

String:

Q8IZQ1

UniGene:

Hs.480116

KEGG:

hsa:23001

Uniprot:

Q8IZQ1

FOR

ELISA Kit for Human WD repeat and FYVE domain-containing protein 3

CLIA Kit for Human WD repeat and FYVE domain-containing protein 3

Polyclonal Antibody for Human WD repeat and FYVE domain-containing protein 3

Monoclonal Antibody for Human WD repeat and FYVE domain-containing protein 3

Protein for Human WD repeat and FYVE domain-containing protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes."
Simonsen A. , Birkeland H.C.G. , Gillooly D.J. , Mizushima N. , Kuma A. , Yoshimori T. , Slagsvold T. , Brech A. , Stenmark H.
J. Cell Sci.117:4239-4251(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Brain.
2.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.6:63-70(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1971-3526 (ISOFORM 1)
tissue: Brain.
4.

"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2381-3036 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2650-3526 (ISOFORM 1)
tissue: Corpus callosum.
tissue: Kidney.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2749-3526 (ISOFORM 1)
tissue: Colon.
tissue: Duodenum.
tissue: Ovary.
7.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy."
Clausen T.H. , Lamark T. , Isakson P. , Finley K. , Larsen K.B. , Brech A. , Overvatn A. , Stenmark H. , Bjorkoy G. , Simonsen A. , Johansen T.
Autophagy6:330-344(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SQSTM1;SUBCELLULAR LOCATION
9.

"Functional interaction between sequestosome-1/p62 and autophagy-linked FYVE-containing protein WDFY3 in human osteoclasts."
Hocking L.J. , Mellis D.J. , McCabe P.S. , Helfrich M.H. , Rogers M.J.
Biochem. Biophys. Res. Commun.402:543-548(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH SQSTM1;TISSUE SPECIFICITY
10.

"The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy."
Filimonenko M. , Isakson P. , Finley K.D. , Anderson M. , Jeong H. , Melia T.J. , Bartlett B.J. , Myers K.M. , Birkeland H.C. , Lamark T. , Krainc D. , Brech A. , Stenmark H. , Simonsen A. , Yamamoto A.
Mol. Cell38:265-279(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ATG5;ASSOCIATION WITH THE ATG12-ATG5-ATG16L COMPLEX;SUBCELLULAR LOCATION
11.

"TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy."
Isakson P. , Lystad A.H. , Breen K. , Koster G. , Stenmark H. , Simonsen A.
Autophagy9:1955-1964(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures."
Lystad A.H. , Ichimura Y. , Takagi K. , Yang Y. , Pankiv S. , Kanegae Y. , Kageyama S. , Suzuki M. , Saito I. , Mizushima T. , Komatsu M. , Simonsen A.
EMBO Rep.15:557-565(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 3341-3354 IN COMPLEX WITH GABARAP;INTERACTION WITH MAP1LC3C; GABARAPL1 AND GABARAPL2;LIR MOTIF;MUTAGENESIS OF LYS-3343; ASP-3344; PHE-3346; ILE-3347; PHE-3348; VAL-3349 AND TYR-3351

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