Wdr34 ELISA Kit for Mouse(Mus musculus) | EIAab.comWdr34 ELISA Kit for Mouse(Mus musculus) | EIAab.com

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Wdr34 (Gene name),

WD repeat-containing protein 34 (Protein name ), WDR34_MOUSE from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

Wdr34;

Protein name:

WD repeat-containing protein 34;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts (via WD domains) with MAP3K7 and TAB3. Interacts (via WD domains) with TAB2 (via C-terminus). Interacts (via WD domains) with TRAF6 (via TRAF-type domains).

Function:

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

535

Sequence:

50:

MCASPRPFRR | VGSAGAAALA | AGGAGGAERR | GRPAPLQDET | LGVASVPSQW |

100:

RSVQGIRGET | KSCQTAGIAT | AESSAQARTH | ADAQVQTEAP | EEPAAMAPVS |

150:

QYDTLRLEAF | LRRVEAMVIR | ELNNNWQSHA | FDGYEVNWTE | QQQTVSCLHT |

200:

LVYPLAQGQG | LHVTGISWNS | TGSVLACAYG | RLDDGDWSTL | KSYVCTWNLD |

250:

RQGLNPQQPS | VVVEVPSAVM | CLAFHPTQPS | HIAGGLYSGE | VLVWDMSRPE |

300:

DPLLWRTGLT | DDTHTDPVYQ | VLWLPEPRHS | HRFQVLSAAT | DGKVLLWRGS |

350:

GAGQLRLTKG | FALAVQQLPR | STKLKKPPRG | ETEVGVTSVA | FSSFDSSLFV |

400:

LGTEGGFPLK | CSLASEVAAL | TRMPSSVPLR | APVQFTFSPH | GGPVYSVSCS |

450:

PFHRNLFLSA | GTDGHVHLYS | MLQAQPLTSL | QLSHKYLFAV | RWSPVRPLVF |

500:

AAASGEGDVQ | LFDLQKSSQK | PTVSITQTQD | GSPVYCLEFN | SQQTQLLAAG |

535:

DAKGMVKVWQ | LSTAFTEQGP | REVEDLDQLE | AEITT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Pfam:

String:

KEGG:

UniGene:

Uniprot:

FOR

ELISA Kit for Mouse WD repeat-containing protein 34

ELISA Kit for Mouse WD repeat-containing protein 34

CLIA Kit for Mouse WD repeat-containing protein 34

CLIA Kit for Mouse WD repeat-containing protein 34

Polyclonal Antibody for Mouse WD repeat-containing protein 34

Polyclonal Antibody for Mouse WD repeat-containing protein 34

Monoclonal Antibody for Mouse WD repeat-containing protein 34

Monoclonal Antibody for Mouse WD repeat-containing protein 34

Protein for Mouse WD repeat-containing protein 34

Protein for Mouse WD repeat-containing protein 34

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Recovery

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Linearity

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-535
strain: C57BL/6.
tissue: Embryonic germ cell.
3.

"WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway."
Gao D. , Wang R. , Li B. , Yang Y. , Zhai Z. , Chen D.Y.
Cell. Mol. Life Sci.66:2573-2584(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy."
Schmidts M. , Vodopiutz J. , Christou-Savina S. , Cortes C.R. , McInerney-Leo A.M. , Emes R.D. , Arts H.H. , Tuysuz B. , D'Silva J. , Leo P.J. , Giles T.C. , Oud M.M. , Harris J.A. , Koopmans M. , Marshall M. , Elcioglu N. , Kuechler A. , Bockenhauer D. , more...
Am. J. Hum. Genet.93:932-944(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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