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Index > Protein center > WDR35(Gene name) > Human
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  • WDR35 (Gene name),
  • WD repeat-containing protein 35 (Protein name ),  WDR35_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    WDR35(IFT121;KIAA1336);
    Protein name:
    WD repeat-containing protein 35;
    Alternative:
    Intraflagellar transport protein 121 homolog;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with IFT43.
    Function:
    May promote CASP3 activation and TNF-stimulated apoptosis. Required for ciliogenesis.
    Subcellular Location:
    Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton cilium axoneme Cytoplasm cytoskeleton cilium basal body
    Protein Attributes:
    Sequence length:
    1181
    Sequence:
    50:
    MFFYLSKKIS | IPNNVKLQCV | SWNKEQGFIA | CGGEDGLLKV | LKLETQTDDA | 
    100:
    KLRGLAAPSN | LSMNQTLEGH | SGSVQVVTWN | EQYQKLTTSD | ENGLIIVWML | 
    150:
    YKGSWIEEMI | NNRNKSVVRS | MSWNADGQKI | CIVYEDGAVI | VGSVDGNRIW | 
    200:
    GKDLKGIQLS | HVTWSADSKV | LLFGMANGEI | HIYDNQGNFM | IKMKLSCLVN | 
    250:
    VTGAISIAGI | HWYHGTEGYV | EPDCPCLAVC | FDNGRCQIMR | HENDQNPVLI | 
    300:
    DTGMYVVGIQ | WNHMGSVLAV | AGFQKAAMQD | KDVNIVQFYT | PFGEHLGTLK | 
    350:
    VPGKEISALS | WEGGGLKIAL | AVDSFIYFAN | IRPNYKWGYC | SNTVVYAYTR | 
    400:
    PDRPEYCVVF | WDTKNNEKYV | KYVKGLISIT | TCGDFCILAT | KADENHPQEE | 
    450:
    NEMETFGATF | VLVLCNSIGT | PLDPKYIDIV | PLFVAMTKTH | VIAASKEAFY | 
    500:
    TWQYRVAKKL | TALEINQITR | SRKEGRERIY | HVDDTPSGSM | DGVLDYSKTI | 
    550:
    QGTRDPICAI | TASDKILIVG | RESGTIQRYS | LPNVGLIQKY | SLNCRAYQLS | 
    600:
    LNCNSSRLAI | IDISGVLTFF | DLDARVTDST | GQQVVGELLK | LERRDVWDMK | 
    650:
    WAKDNPDLFA | MMEKTRMYVF | RNLDPEEPIQ | TSGYICNFED | LEIKSVLLDE | 
    700:
    ILKDPEHPNK | DYLINFEIRS | LRDSRALIEK | VGIKDASQFI | EDNPHPRLWR | 
    750:
    LLAEAALQKL | DLYTAEQAFV | RCKDYQGIKF | VKRLGKLLSE | SMKQAEVVGY | 
    800:
    FGRFEEAERT | YLEMDRRDLA | IGLRLKLGDW | FRVLQLLKTG | SGDADDSLLE | 
    850:
    QANNAIGDYF | ADRQKWLNAV | QYYVQGRNQE | RLAECYYMLE | DYEGLENLAI | 
    900:
    SLPENHKLLP | EIAQMFVRVG | MCEQAVTAFL | KCSQPKAAVD | TCVHLNQWNK | 
    950:
    AVELAKNHSM | KEIGSLLARY | ASHLLEKNKT | LDAIELYRKA | NYFFDAAKLM | 
    1000:
    FKIADEEAKK | GSKPLRVKKL | YVLSALLIEQ | YHEQMKNAQR | GKVKGKSSEA | 
    1050:
    TSALAGLLEE | EVLSTTDRFT | DNAWRGAEAY | HFFILAQRQL | YEGCVDTALK | 
    1100:
    TALHLKDYED | IIPPVEIYSL | LALCACASRA | FGTCSKAFIK | LKSLETLSSE | 
    1150:
    QKQQYEDLAL | EIFTKHTSKD | NRKPELDSLM | EGGEGKLPTC | VATGSPITEY | 
    1181:
    QFWMCSVCKH | GVLAQEISHY | SFCPLCHSPV | G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    KEGG:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human WD repeat-containing protein 35
    ELISA Kit for Human WD repeat-containing protein 35
    ELISA Kit for Human WD repeat-containing protein 35
    CLIA Kit for Human WD repeat-containing protein 35
    CLIA Kit for Human WD repeat-containing protein 35
    CLIA Kit for Human WD repeat-containing protein 35
    Polyclonal Antibody for Human WD repeat-containing protein 35
    Polyclonal Antibody for Human WD repeat-containing protein 35
    Polyclonal Antibody for Human WD repeat-containing protein 35
    Monoclonal Antibody for Human WD repeat-containing protein 35
    Monoclonal Antibody for Human WD repeat-containing protein 35
    Monoclonal Antibody for Human WD repeat-containing protein 35
    Protein for Human WD repeat-containing protein 35
    Protein for Human WD repeat-containing protein 35
    Protein for Human WD repeat-containing protein 35

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Kikuno R. , Ishikawa K. , Hirosawa M. , Ohara O.
      DNA Res.7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    2. 2.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLY-983
      tissue: Testis.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT THR-878
      tissue: Testis.
    7. 7.
      "SnapShot: Intraflagellar transport."
      Cole D.G. , Snell W.J.
      Cell137:784-784(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IFT43
    8. 8.
      "Naofen, a novel WD40-repeat protein, mediates spontaneous and tumor necrosis factor-induced apoptosis."
      Feng G.G. , Li C. , Huang L. , Tsunekawa K. , Sato Y. , Fujiwara Y. , Komatsu T. , Honda T. , Fan J.H. , Goto H. , Koide T. , Hasegawa T. , Ishikawa N.
      Biochem. Biophys. Res. Commun.394:153-157(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    9. 9.
      "TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia."
      Mukhopadhyay S. , Wen X. , Chih B. , Nelson C.D. , Lane W.S. , Scales S.J. , Jackson P.K.
      Genes Dev.24:2180-2193(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE IFT-A COMPLEX
    10. 10.
      "Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis."
      Mill P. , Lockhart P.J. , Fitzpatrick E. , Mountford H.S. , Hall E.A. , Reijns M.A. , Keighren M. , Bahlo M. , Bromhead C.J. , Budd P. , Aftimos S. , Delatycki M.B. , Savarirayan R. , Jackson I.J. , Amor D.J.
      Am. J. Hum. Genet.88:508-515(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;VARIANT SRTD7 ARG-261
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CED2 GLY-626 AND THR-875
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