Gene name:
WHAMM (KIAA1971;WHDC1) ;
Protein name:
WASP homolog-associated protein with actin, membranes and microtubules ;
Alternative:
WAS protein homology region 2 domain-containing protein 1 (WH2 domain-containing protein 1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with actin, ACTR3 and microtubules.
Function:
Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
Subcellular Location:
Cytoplasm
Endoplasmic reticulum-Golgi intermediate compartment
Cytoplasmic vesicle membrane
Golgi apparatus
cis-Golgi network
Localized to a perinuclear compartment near the microtubule-organizing center (MTOC). Also detected on tubulo-vesicular structures in the cell periphery that frequently localized along microtubules.
Protein Attributes:
50:
MEDEQPDSLE | GWVPVREGLF | AEPERHRLRF | LVAWNGAEGK | FAVTCHDRTA |
100:
QQRRLREGAR | LGPEPEPKPE | AAVSPSSWAG | LLSAAGLRGA | HRQLAALWPP |
150:
LERCFPRLPP | ELDVGGGGAW | GLGLGLWALL | WPTRAGPGEA | ALQELCGQLE |
200:
RYLGAAADGC | GGATVRDALF | PAEGGAADCE | SPREFRERAL | RARWVEADAR |
250:
LRQVIQGHGK | ANTMVALMNV | YQEEDEAYQE | LVTVATMFFQ | YLLQPFRAMR |
300:
EVATLCKLDI | LKSLDEDDLG | PRRVVALEKE | AEEWTRRAEE | AVVSIQDITV |
350:
NYFKETVKAL | AGMQKEMEQD | AKRFGQAAWA | TAIPRLEKLQ | LMLARETLQL |
400:
MRAKELCLNH | KRAEIQGKME | DLPEQEKNTN | VVDELEIQFY | EIQLELYEVK |
450:
FEILKNEEIL | LTTQLDSLKR | LIKEKQDEVV | YYDPCENPEE | LKVIDCVVGL |
500:
QDDKNLEVKE | LRRQCQQLES | KRGRICAKRA | SLRSRKDQCK | ENHRFRLQQA |
550:
EESIRYSRQH | HSIQMKRDKI | KEEEQKKKEW | INQERQKTLQ | RLRSFKDKRL |
600:
AQSVRNTSGS | EPVAPNLPSD | LSQQMCLPAS | HAVSVIHPSS | RKTRGVPLSE |
650:
AGNVKSPKCQ | NCHGNIPVQV | FVPVGDQTHS | KSSEELSLPP | PPPPPPPPPP |
700:
PPPPPPPPLR | ALSSSSQAAT | HQNLGFRAPV | KDDQPRPLVC | ESPAERPRDS |
750:
LESFSCPGSM | DEVLASLRHG | RAPLRKVEVP | AVRPPHASIN | EHILAAIRQG |
800:
VKLKKVHPDL | GPNPSSKPTS | NRRTSDLERS | IKAALQRIKR | VSADSEEDSD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human WASP homolog-associated protein with actin, membranes and microtubules
ELISA Kit for Human WASP homolog-associated protein with actin, membranes and microtubules
CLIA Kit for Human WASP homolog-associated protein with actin, membranes and microtubules
CLIA Kit for Human WASP homolog-associated protein with actin, membranes and microtubules
Polyclonal Antibody for Human WASP homolog-associated protein with actin, membranes and microtubules
Polyclonal Antibody for Human WASP homolog-associated protein with actin, membranes and microtubules
Monoclonal Antibody for Human WASP homolog-associated protein with actin, membranes and microtubules
Monoclonal Antibody for Human WASP homolog-associated protein with actin, membranes and microtubules
Protein for Human WASP homolog-associated protein with actin, membranes and microtubules
Protein for Human WASP homolog-associated protein with actin, membranes and microtubules
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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