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Index > Protein center > Whamm(Gene name) > Mouse
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  • Whamm (Gene name),
  • WASP homolog-associated protein with actin, membranes and microtubules (Protein name ),  WHAMM_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Whamm(Kiaa1971;Whdc1);
    Protein name:
    WASP homolog-associated protein with actin, membranes and microtubules;
    Alternative:
    WAS protein homology region 2 domain-containing protein 1(WH2 domain-containing protein 1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with actin, ACTR3 and microtubules.
    Function:
    Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes (By similarity). Involved as a regulator of Golgi positioning and morphology (By similarity). Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
    Subcellular Location:
    Cytoplasm Endoplasmic reticulum-Golgi intermediate compartment Cytoplasmic vesicle membrane Golgi apparatus cis-Golgi network Localized to a perinuclear compartment near the microtubule-organizing center (MTOC). Also detected on tubulo-vesicular structures in the cell periphery that frequently localized along microtubules.
    Protein Attributes:
    Sequence length:
    793
    Sequence:
    50:
    MDSEQPDSLD | GWVPLREDLF | PEPERHQLRF | LVAWNAAKGQ | FAVTCHDRTA | 
    100:
    QRRRRERREA | GDGGCSWAGV | LSPAGFRGAH | RQLAALWPAL | EPCFPPLPPE | 
    150:
    LDAASGAGWG | LGRGLWALLW | PLLWPAPADP | GDSALQELCR | QLEHYLGLAA | 
    200:
    EGCGGATVRD | VLFPAPGDSA | DCEGLSEFRE | RTLRARLGQT | ATRLHQVLQD | 
    250:
    HGKANTMVAL | MKVYQEEDEL | YQELVTMATT | FFQYLLQPFR | DMREVATSCK | 
    300:
    LGILKSLDED | ELGPRRVAAL | QKEASEWTRQ | AEEAVGSIQD | ITVNYFKETV | 
    350:
    TALTGMQKQM | EQDQKRFGQA | AWATAMPRLE | NLKLMLARET | LQLMRAKELC | 
    400:
    LKHRQAEIQR | KVEDLPRQGK | QLDVVDELEI | QCYEIQLELY | DVKLEMLRNE | 
    450:
    ETILVTRLDS | VKRLITEKQA | EVIYYDPCES | PEELQSLAPD | LELHLGDNRE | 
    500:
    LRALSQQCQR | LEAQRGRICS | RRALLRNRKD | HCRENHQLRL | QQAKQSLRHL | 
    550:
    HQHHSIQMKR | DKVKEEEQKK | KEWIDHERQK | TLERLRAYKE | KCPAHRSALK | 
    600:
    TTCSESMVSN | LPGGRSQKRL | STAHHHKTAH | PASSKTGSAV | PLPEASVRPP | 
    650:
    EHQDPCGSVP | VQAFVPVSDQ | TLSGSSEDLS | LPPQPPAPPL | PPPPPPPPPP | 
    700:
    PLPPALSSFQ | GTTHQNLGLR | TLATEDRPLP | LACDPSAGRP | CDYQGPGSMD | 
    750:
    EVLASLRQGK | ASLRKVETPT | LPHPGTSVNE | QVLAAIRQGV | QLKKVHTGQG | 
    793:
    VDPGKKSTSD | LERSIREALE | RIKKVSADSE | EDNDEPSPTE | WDR
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    ELISA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    CLIA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    CLIA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Polyclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Polyclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Monoclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Monoclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Protein for Mouse WASP homolog-associated protein with actin, membranes and microtubules
    Protein for Mouse WASP homolog-associated protein with actin, membranes and microtubules

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      strain: C57BL/6J.
      tissue: Adipose tissue.
    2. 2.
      "Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R.F. , Ohara R. , Inamoto S. , Nagase T. , Ohara O. , Koga H.
      Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Pancreatic islet.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4)
      strain: FVB/N.
      tissue: Mammary tumor.
      tissue: Testis.
    4. 4.
      "WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport."
      Campellone K.G. , Webb N.J. , Znameroski E.A. , Welch M.D.
      Cell134:148-161(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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