Gene name:
Whamm (Kiaa1971;Whdc1) ;
Protein name:
WASP homolog-associated protein with actin, membranes and microtubules ;
Alternative:
WAS protein homology region 2 domain-containing protein 1 (WH2 domain-containing protein 1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with actin, ACTR3 and microtubules.
Function:
Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes (By similarity). Involved as a regulator of Golgi positioning and morphology (By similarity). Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
Subcellular Location:
Cytoplasm
Endoplasmic reticulum-Golgi intermediate compartment
Cytoplasmic vesicle membrane
Golgi apparatus
cis-Golgi network
Localized to a perinuclear compartment near the microtubule-organizing center (MTOC). Also detected on tubulo-vesicular structures in the cell periphery that frequently localized along microtubules.
Protein Attributes:
50:
MDSEQPDSLD | GWVPLREDLF | PEPERHQLRF | LVAWNAAKGQ | FAVTCHDRTA |
100:
QRRRRERREA | GDGGCSWAGV | LSPAGFRGAH | RQLAALWPAL | EPCFPPLPPE |
150:
LDAASGAGWG | LGRGLWALLW | PLLWPAPADP | GDSALQELCR | QLEHYLGLAA |
200:
EGCGGATVRD | VLFPAPGDSA | DCEGLSEFRE | RTLRARLGQT | ATRLHQVLQD |
250:
HGKANTMVAL | MKVYQEEDEL | YQELVTMATT | FFQYLLQPFR | DMREVATSCK |
300:
LGILKSLDED | ELGPRRVAAL | QKEASEWTRQ | AEEAVGSIQD | ITVNYFKETV |
350:
TALTGMQKQM | EQDQKRFGQA | AWATAMPRLE | NLKLMLARET | LQLMRAKELC |
400:
LKHRQAEIQR | KVEDLPRQGK | QLDVVDELEI | QCYEIQLELY | DVKLEMLRNE |
450:
ETILVTRLDS | VKRLITEKQA | EVIYYDPCES | PEELQSLAPD | LELHLGDNRE |
500:
LRALSQQCQR | LEAQRGRICS | RRALLRNRKD | HCRENHQLRL | QQAKQSLRHL |
550:
HQHHSIQMKR | DKVKEEEQKK | KEWIDHERQK | TLERLRAYKE | KCPAHRSALK |
600:
TTCSESMVSN | LPGGRSQKRL | STAHHHKTAH | PASSKTGSAV | PLPEASVRPP |
650:
EHQDPCGSVP | VQAFVPVSDQ | TLSGSSEDLS | LPPQPPAPPL | PPPPPPPPPP |
700:
PLPPALSSFQ | GTTHQNLGLR | TLATEDRPLP | LACDPSAGRP | CDYQGPGSMD |
750:
EVLASLRQGK | ASLRKVETPT | LPHPGTSVNE | QVLAAIRQGV | QLKKVHTGQG |
793:
VDPGKKSTSD | LERSIREALE | RIKKVSADSE | EDNDEPSPTE | WDR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
ELISA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
CLIA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
CLIA Kit for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Polyclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Polyclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Monoclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Monoclonal Antibody for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Protein for Mouse WASP homolog-associated protein with actin, membranes and microtubules
Protein for Mouse WASP homolog-associated protein with actin, membranes and microtubules
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
strain :
C57BL/6J .
tissue :
Adipose tissue .
2.
"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.F.
,
Ohara R.
,
Inamoto S.
,
Nagase T.
,
Ohara O.
,
Koga H.
Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Pancreatic islet .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4)
strain :
FVB/N .
tissue :
Mammary tumor .
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION