Wipf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comWipf1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Wipf1(Gene name) > Rat

Wipf1 (Gene name),

WAS/WASL-interacting protein family member 1 (Protein name ), WIPF1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Wipf1(Waspip;Wip);

Protein name:

WAS/WASL-interacting protein family member 1;

Alternative:

Wiskott-Aldrich syndrome protein-interacting protein(WASP-interacting protein);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds to WAS within the N-terminal region, at a site distinct from the CDC42-binding site. Binds profilin and actin (By similarity). Binds to WASL.

Function:

May have direct activity on the actin cytoskeleton. Induces actin polymerization and redistribution. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL (By similarity). May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation.

Subcellular Location:

Cytoplasmic vesicle Cytoplasm cytoskeleton Vesicle surfaces and along actin tails. Co-localized with actin stress fibers. When co-expressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL.

Protein Attributes:

Sequence length:

487

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

487:

PYVPTTKTYP | SKVARSESRS | GSNRRERGAP | PLPPIPR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000024922

Pfam:

PF02205

String:

Q6IN36

KEGG:

rno:117538

UniGene:

Rn.161803

SMR:

Q6IN36

Uniprot:

Q6IN36

FOR

ELISA Kit for Rat WAS/WASL-interacting protein family member 1

CLIA Kit for Rat WAS/WASL-interacting protein family member 1

Polyclonal Antibody for Rat WAS/WASL-interacting protein family member 1

Monoclonal Antibody for Rat WAS/WASL-interacting protein family member 1

Protein for Rat WAS/WASL-interacting protein family member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation."
Vetterkind S. , Miki H. , Takenawa T. , Klawitz I. , Scheidtmann K.-H. , Preuss U.
J. Biol. Chem.277:87-95(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH WASL
strain: Fischer 344.
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.

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