Gene name:
WISP2 (UNQ228/PRO261;CCN5;CT58;CTGFL) ;
Protein name:
WNT1-inducible-signaling pathway protein 2 (WISP-2) ;
Alternative:
Connective tissue growth factor-like protein (CTGF-L) ;CCN family member 5 ;Connective tissue growth factor-related protein 58 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRGTPKTHLL | AFSLLCLLSK | VRTQLCPTPC | TCPWPPPRCP | LGVPLVLDGC |
100:
GCCRVCARRL | GEPCDQLHVC | DASQGLVCQP | GAGPGGRGAL | CLLAEDDSSC |
150:
EVNGRLYREG | ETFQPHCSIR | CRCEDGGFTC | VPLCSEDVRL | PSWDCPHPRR |
200:
VEVLGKCCPE | WVCGQGGGLG | TQPLPAQGPQ | FSGLVSSLPP | GVPCPEWSTA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Human WISP-2
ELISA Kit for Human WISP-2
ELISA Kit for Human WISP-2
CLIA Kit for Human WISP-2
CLIA Kit for Human WISP-2
CLIA Kit for Human WISP-2
Polyclonal Antibody for Human WISP-2
Polyclonal Antibody for Human WISP-2
Polyclonal Antibody for Human WISP-2
Monoclonal Antibody for Human WISP-2
Monoclonal Antibody for Human WISP-2
Monoclonal Antibody for Human WISP-2
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions."
Kumar S.
,
Hand A.T.
,
Connor J.R.
,
Dodds R.A.
,
Ryan P.J.
,
Trill J.J.
,
Fisher S.M.
,
Nuttall M.E.
,
Lipshutz D.B.
,
Zou C.
,
Hwang S.M.
,
Votta B.J.
,
James I.E.
,
Rieman D.J.
,
Gowen M.
,
Lee J.C.
J. Biol. Chem.274:17123-17131(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
"CT58, a new member of the connective tissue growth factor family, interacts with the breast cancer associated mucin MUC1."
Rowles J.
,
Gendler S.
Submitted (1998-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.
"WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors."
Pennica D.
,
Swanson T.A.
,
Welsh J.W.
,
Roy M.A.
,
Lawrence D.A.
,
Lee J.
,
Brush J.
,
Taneyhill L.A.
,
Deuel B.
,
Lew M.
,
Watanabe C.
,
Cohen R.L.
,
Melham M.F.
,
Finley G.G.
,
Quirke P.
,
Goddard A.D.
,
Hillan K.J.
,
Gurney A.L.
,
Botstein D.
,
Levine A.J.
more...
Proc. Natl. Acad. Sci. U.S.A.95:14717-14722(1998)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Lung .
4.
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F.
,
Gurney A.L.
,
Abaya E.
,
Baker K.
,
Baldwin D.T.
,
Brush J.
,
Chen J.
,
Chow B.
,
Chui C.
,
Crowley C.
,
Currell B.
,
Deuel B.
,
Dowd P.
,
Eaton D.
,
Foster J.S.
,
Grimaldi C.
,
Gu Q.
,
Hass P.E.
,
Heldens S.
,
Huang A.
,
Kim H.S.
,
Klimowski L.
,
Jin Y.
,
Johnson S.
,
Lee J.
,
Lewis L.
,
Liao D.
,
Mark M.R.
,
Robbie E.
,
Sanchez C.
,
Schoenfeld J.
,
Seshagiri S.
,
Simmons L.
,
Singh J.
,
Smith V.
,
Stinson J.
,
Vagts A.
,
Vandlen R.L.
,
Watanabe C.
,
Wieand D.
,
Woods K.
,
Xie M.-H.
,
Yansura D.G.
,
Yi S.
,
Yu G.
,
Yuan J.
,
Zhang M.
,
Zhang Z.
,
Goddard A.D.
,
Wood W.I.
,
Godowski P.J.
,
Gray A.M.
more...
Genome Res.13:2265-2270(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Skeletal muscle .
6.
"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P.
,
Matthews L.H.
,
Ashurst J.L.
,
Burton J.
,
Gilbert J.G.R.
,
Jones M.
,
Stavrides G.
,
Almeida J.P.
,
Babbage A.K.
,
Bagguley C.L.
,
Bailey J.
,
Barlow K.F.
,
Bates K.N.
,
Beard L.M.
,
Beare D.M.
,
Beasley O.P.
,
Bird C.P.
,
Blakey S.E.
,
Bridgeman A.M.
,
Brown A.J.
,
Buck D.
,
Burrill W.D.
,
Butler A.P.
,
Carder C.
,
Carter N.P.
,
Chapman J.C.
,
Clamp M.
,
Clark G.
,
Clark L.N.
,
Clark S.Y.
,
Clee C.M.
,
Clegg S.
,
Cobley V.E.
,
Collier R.E.
,
Connor R.E.
,
Corby N.R.
,
Coulson A.
,
Coville G.J.
,
Deadman R.
,
Dhami P.D.
,
Dunn M.
,
Ellington A.G.
,
Frankland J.A.
,
Fraser A.
,
French L.
,
Garner P.
,
Grafham D.V.
,
Griffiths C.
,
Griffiths M.N.D.
,
Gwilliam R.
,
Hall R.E.
,
Hammond S.
,
Harley J.L.
,
Heath P.D.
,
Ho S.
,
Holden J.L.
,
Howden P.J.
,
Huckle E.
,
Hunt A.R.
,
Hunt S.E.
,
Jekosch K.
,
Johnson C.M.
,
Johnson D.
,
Kay M.P.
,
Kimberley A.M.
,
King A.
,
Knights A.
,
Laird G.K.
,
Lawlor S.
,
Lehvaeslaiho M.H.
,
Leversha M.A.
,
Lloyd C.
,
Lloyd D.M.
,
Lovell J.D.
,
Marsh V.L.
,
Martin S.L.
,
McConnachie L.J.
,
McLay K.
,
McMurray A.A.
,
Milne S.A.
,
Mistry D.
,
Moore M.J.F.
,
Mullikin J.C.
,
Nickerson T.
,
Oliver K.
,
Parker A.
,
Patel R.
,
Pearce T.A.V.
,
Peck A.I.
,
Phillimore B.J.C.T.
,
Prathalingam S.R.
,
Plumb R.W.
,
Ramsay H.
,
Rice C.M.
,
Ross M.T.
,
Scott C.E.
,
Sehra H.K.
,
Shownkeen R.
,
Sims S.
,
Skuce C.D.
,
Smith M.L.
,
Soderlund C.
,
Steward C.A.
,
Sulston J.E.
,
Swann R.M.
,
Sycamore N.
,
Taylor R.
,
Tee L.
,
Thomas D.W.
,
Thorpe A.
,
Tracey A.
,
Tromans A.C.
,
Vaudin M.
,
Wall M.
,
Wallis J.M.
,
Whitehead S.L.
,
Whittaker P.
,
Willey D.L.
,
Williams L.
,
Williams S.A.
,
Wilming L.
,
Wray P.W.
,
Hubbard T.
,
Durbin R.M.
,
Bentley D.R.
,
Beck S.
,
Rogers J.
more...
Nature414:865-871(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
tissue :
Lung .
tissue :
Ovary .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 24-38