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Index > Protein center > Wls(Gene name) > Mouse
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  • Wls (Gene name),
  • Protein wntless homolog (Protein name ),  WLS_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Wls(Gpr177);
    Protein name:
    Protein wntless homolog;
    Alternative:
    Protein evenness interrupted homolog(EVI);Integral membrane protein GPR177;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with WNT3A (By similarity). Interacts with WNT1, WNT3 and WNT5.
    Function:
    Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
    Subcellular Location:
    Golgi apparatus membrane Multi-pass membrane protein Cytoplasmic vesicle membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    541
    Sequence:
    50:
    MAGAIIENMS | TKKLCIVGGI | LLVFQIVAFL | VGGLIAPAPT | TAVPYTAIKC | 
    100:
    VDVRKNHHKT | RWLAPWGPNK | CDKIRDIEEA | IPREIEANDI | VFSVHIPLPS | 
    150:
    MEMSPWFQFM | LFILQLDIAF | KLNNQIRENA | EISMDVSLGY | RDDMFSEWTE | 
    200:
    MAHERVPRKL | KCTFTSPKTP | EHEGRYYNCD | VLPFMEIGSV | AHKYYLLNIR | 
    250:
    LPVNEKKKIN | VGIGEIKDIR | LVGIHQNGGF | TKVWFAMKTF | LTPSIFIIMV | 
    300:
    WYWRRITMMS | RPPVLLEKVI | FALGISMTFI | NIPVEWFSIG | FDWTWMLLFG | 
    350:
    DIRQGIFYAM | LLSFWIIFCG | EHMMDQHERN | HIAGYWKQVG | PIAVGSFCLF | 
    400:
    IFDMCERGVQ | LTNPFYSIWT | TDVGTELAMA | FIIVAGICLC | LYFLFLCFMV | 
    450:
    FQVFRNISGK | QSSLPAMSKV | RRLHYEGLIF | RFKFLMLITL | ACAAMTVIFF | 
    500:
    IVSQVSEGHW | KWGGVTVQVS | SAFFTGIYGM | WNLYVFALMF | LYAPSHKNYG | 
    541:
    EDQSNGDLGV | HSGEELQLTT | TITHVDGPTE | IYKLTRKEAQ | E
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Protein wntless homolog
    ELISA Kit for Mouse Protein wntless homolog
    ELISA Kit for Mouse Protein wntless homolog
    ELISA Kit for Mouse Protein wntless homolog
    CLIA Kit for Mouse Protein wntless homolog
    CLIA Kit for Mouse Protein wntless homolog
    CLIA Kit for Mouse Protein wntless homolog
    CLIA Kit for Mouse Protein wntless homolog
    Polyclonal Antibody for Mouse Protein wntless homolog
    Polyclonal Antibody for Mouse Protein wntless homolog
    Polyclonal Antibody for Mouse Protein wntless homolog
    Polyclonal Antibody for Mouse Protein wntless homolog
    Monoclonal Antibody for Mouse Protein wntless homolog
    Monoclonal Antibody for Mouse Protein wntless homolog
    Monoclonal Antibody for Mouse Protein wntless homolog
    Monoclonal Antibody for Mouse Protein wntless homolog
    Protein for Mouse Protein wntless homolog
    Protein for Mouse Protein wntless homolog
    Protein for Mouse Protein wntless homolog
    Protein for Mouse Protein wntless homolog

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    Precision
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Head.
      tissue: Hippocampus.
      tissue: Ovary.
      tissue: Skin.
      tissue: Uterus.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation."
      Fu J. , Jiang M. , Mirando A.J. , Yu H.-M. , Hsu W.
      Proc. Natl. Acad. Sci. U.S.A.106:18598-18603(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE;DEVELOPMENTAL STAGE;INTERACTION WITH WNT1; WNT3 AND WNT5A
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