Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > WNK1(Gene name) > Human
  • Add your favorite
  • WNK1 (Gene name),
  • Serine/threonine-protein kinase WNK1 (Protein name ),  WNK1_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    WNK1(HSN2;KDP;KIAA0344;PRKWNK1);
    Protein name:
    Serine/threonine-protein kinase WNK1;
    Alternative:
    Kinase deficient protein;Erythrocyte 65 kDa protein(p65);Protein kinase with no lysine 1(hWNK1);Protein kinase lysine-deficient 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with SYT2 (By similarity). Interacts with WNK3 and WNK4.
    Function:
    Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    2382
    Sequence:
    50:
    MSGGAAEKQS | STPGSLFLSP | PAPAPKNGSS | SDSSVGEKLG | AAAADAVTGR | 
    100:
    TEEYRRRRHT | MDKDSRGAAA | TTTTTEHRFF | RRSVICDSNA | TALELPGLPL | 
    150:
    SLPQPSIPAA | VPQSAPPEPH | REETVTATAT | SQVAQQPPAA | AAPGEQAVAG | 
    200:
    PAPSTVPSST | SKDRPVSQPS | LVGSKEEPPP | ARSGSGGGSA | KEPQEERSQQ | 
    250:
    QDDIEELETK | AVGMSNDGRF | LKFDIEIGRG | SFKTVYKGLD | TETTVEVAWC | 
    300:
    ELQDRKLTKS | ERQRFKEEAE | MLKGLQHPNI | VRFYDSWEST | VKGKKCIVLV | 
    350:
    TELMTSGTLK | TYLKRFKVMK | IKVLRSWCRQ | ILKGLQFLHT | RTPPIIHRDL | 
    400:
    KCDNIFITGP | TGSVKIGDLG | LATLKRASFA | KSVIGTPEFM | APEMYEEKYD | 
    450:
    ESVDVYAFGM | CMLEMATSEY | PYSECQNAAQ | IYRRVTSGVK | PASFDKVAIP | 
    500:
    EVKEIIEGCI | RQNKDERYSI | KDLLNHAFFQ | EETGVRVELA | EEDDGEKIAI | 
    550:
    KLWLRIEDIK | KLKGKYKDNE | AIEFSFDLER | DVPEDVAQEM | VESGYVCEGD | 
    600:
    HKTMAKAIKD | RVSLIKRKRE | QRQLVREEQE | KKKQEESSLK | QQVEQSSASQ | 
    650:
    TGIKQLPSAS | TGIPTASTTS | ASVSTQVEPE | EPEADQHQQL | QYQQPSISVL | 
    700:
    SDGTVDSGQG | SSVFTESRVS | SQQTVSYGSQ | HEQAHSTGTV | PGHIPSTVQA | 
    750:
    QSQPHGVYPP | SSVAQGQSQG | QPSSSSLTGV | SSSQPIQHPQ | QQQGIQQTAP | 
    800:
    PQQTVQYSLS | QTSTSSEATT | AQPVSQPQAP | QVLPQVSAGK | QLPVSQPVPT | 
    850:
    IQGEPQIPVA | TQPSVVPVHS | GAHFLPVGQP | LPTPLLPQYP | VSQIPISTPH | 
    900:
    VSTAQTGFSS | LPITMAAGIT | QPLLTLASSA | TTAAIPGVST | VVPSQLPTLL | 
    950:
    QPVTQLPSQV | HPQLLQPAVQ | SMGIPANLGQ | AAEVPLSSGD | VLYQGFPPRL | 
    1000:
    PPQYPGDSNI | APSSNVASVC | IHSTVLSPPM | PTEVLATPGY | FPTVVQPYVE | 
    1050:
    SNLLVPMGGV | GGQVQVSQPG | GSLAQAPTTS | SQQAVLESTQ | GVSQVAPAEP | 
    1100:
    VAVAQTQATQ | PTTLASSVDS | AHSDVASGMS | DGNENVPSSS | GRHEGRTTKR | 
    1150:
    HYRKSVRSRS | RHEKTSRPKL | RILNVSNKGD | RVVECQLETH | NRKMVTFKFD | 
    1200:
    LDGDNPEEIA | TIMVNNDFIL | AIERESFVDQ | VREIIEKADE | MLSEDVSVEP | 
    1250:
    EGDQGLESLQ | GKDDYGFSGS | QKLEGEFKQP | IPASSMPQQI | GIPTSSLTQV | 
    1300:
    VHSAGRRFIV | SPVPESRLRE | SKVFPSEITD | TVAASTAQSP | GMNLSHSASS | 
    1350:
    LSLQQAFSEL | RRAQMTEGPN | TAPPNFSHTG | PTFPVVPPFL | SSIAGVPTTA | 
    1400:
    AATAPVPATS | SPPNDISTSV | IQSEVTVPTE | EGIAGVATST | GVVTSGGLPI | 
    1450:
    PPVSESPVLS | SVVSSITIPA | VVSISTTSPS | LQVPTSTSEI | VVSSTALYPS | 
    1500:
    VTVSATSASA | GGSTATPGPK | PPAVVSQQAA | GSTTVGATLT | SVSTTTSFPS | 
    1550:
    TASQLCIQLS | SSTSTPTLAE | TVVVSAHSLD | KTSHSSTTGL | AFSLSAPSSS | 
    1600:
    SSPGAGVSSY | ISQPGGLHPL | VIPSVIASTP | ILPQAAGPTS | TPLLPQVPSI | 
    1650:
    PPLVQPVANV | PAVQQTLIHS | QPQPALLPNQ | PHTHCPEVDS | DTQPKAPGID | 
    1700:
    DIKTLEEKLR | SLFSEHSSSG | AQHASVSLET | SLVIESTVTP | GIPTTAVAPS | 
    1750:
    KLLTSTTSTC | LPPTNLPLGT | VALPVTPVVT | PGQVSTPVST | TTSGVKPGTA | 
    1800:
    PSKPPLTKAP | VLPVGTELPA | GTLPSEQLPP | FPGPSLTQSQ | QPLEDLDAQL | 
    1850:
    RRTLSPEMIT | VTSAVGPVSM | AAPTAITEAG | TQPQKGVSQV | KEGPVLATSS | 
    1900:
    GAGVFKMGRF | QVSVAADGAQ | KEGKNKSEDA | KSVHFESSTS | ESSVLSSSSP | 
    1950:
    ESTLVKPEPN | GITIPGISSD | VPESAHKTTA | SEAKSDTGQP | TKVGRFQVTT | 
    2000:
    TANKVGRFSV | SKTEDKITDT | KKEGPVASPP | FMDLEQAVLP | AVIPKKEKPE | 
    2050:
    LSEPSHLNGP | SSDPEAAFLS | RDVDDGSGSP | HSPHQLSSKS | LPSQNLSQSL | 
    2100:
    SNSFNSSYMS | SDNESDIEDE | DLKLELRRLR | DKHLKEIQDL | QSRQKHEIES | 
    2150:
    LYTKLGKVPP | AVIIPPAAPL | SGRRRRPTKS | KGSKSSRSSS | LGNKSPQLSG | 
    2200:
    NLSGQSAASV | LHPQQTLHPP | GNIPESGQNQ | LLQPLKPSPS | SDNLYSAFTS | 
    2250:
    DGAISVPSLS | APGQGTSSTN | TVGATVNSQA | AQAQPPAMTS | SRKGTFTDDL | 
    2300:
    HKLVDNWARD | AMNLSGRRGS | KGHMNYEGPG | MARKFSAPGQ | LCISMTSNLG | 
    2350:
    GSAPISAASA | TSLGHFTKSM | CPPQQYGFPA | TPFGAQWSGT | GGPAPQPLGQ | 
    2382:
    FQPVGTASLQ | NFNISNLQKS | ISNPPGSNLR | TT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    UniGene:
    Pfam:
    KEGG:
    MIM:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Serine/threonine-protein kinase WNK1
    ELISA Kit for Human Serine/threonine-protein kinase WNK1
    ELISA Kit for Human Serine/threonine-protein kinase WNK1
    ELISA Kit for Human Serine/threonine-protein kinase WNK1
    CLIA Kit for Human Serine/threonine-protein kinase WNK1
    CLIA Kit for Human Serine/threonine-protein kinase WNK1
    CLIA Kit for Human Serine/threonine-protein kinase WNK1
    CLIA Kit for Human Serine/threonine-protein kinase WNK1
    Polyclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Polyclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Polyclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Polyclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Monoclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Monoclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Monoclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Monoclonal Antibody for Human Serine/threonine-protein kinase WNK1
    Protein for Human Serine/threonine-protein kinase WNK1
    Protein for Human Serine/threonine-protein kinase WNK1
    Protein for Human Serine/threonine-protein kinase WNK1
    Protein for Human Serine/threonine-protein kinase WNK1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms."
      Verissimo F. , Jordan P.
      Oncogene20:5562-5569(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;CHROMOSOMAL LOCATION;VARIANTS PRO-1056; SER-1506 AND ILE-1808
      tissue: Heart.
    2. 2.
      "A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms."
      Vidal-Petiot E. , Cheval L. , Faugeroux J. , Malard T. , Doucet A. , Jeunemaitre X. , Hadchouel J.
      PLoS ONE7:E37751-E37751(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
      tissue: Neuron.
    3. 3.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2008-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS PRO-1056; SER-1506 AND ILE-1808
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the JNK MAPK pathway and regulates actin cytoskeletal organisation."
      Moore T.M. , Garg R. , Johnson C. , Coptcoat M.J. , Ridley A.J. , Morris J.D.H.
      J. Biol. Chem.275:4311-4322(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-668 (ISOFORMS 1/2);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Mammary carcinoma.
    6. 6.
      "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Nakajima D. , Ohira M. , Seki N. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 69-2382 (ISOFORM 2);VARIANTS PRO-1056 AND SER-1506
      tissue: Brain.
    7. 7.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO N-TERMINUS
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 163-175;GLYCOSYLATION
    9. 9.
      "Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform."
      Delaloy C. , Lu J. , Houot A.-M. , Disse-Nicodeme S. , Gasc J.-M. , Corvol P. , Jeunemaitre X.
      Mol. Cell. Biol.23:9208-9221(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (N-TERMINUS OF ISOFORM 3);ALTERNATIVE PROMOTER USAGE;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
      tissue: Kidney.
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1/4/5)
      tissue: Placenta.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION (ISOFORMS 4/5);FUNCTION;INVOLVEMENT IN HSAN2A
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PHA2C
    13. 13.
      "Two mutations in the HSN2 gene explain the high prevalence of HSAN2 in French Canadians."
      Roddier K. , Thomas T. , Marleau G. , Gagnon A.M. , Dicaire M.J. , St Denis A. , Gosselin I. , Sarrazin A.M. , Larbrisseau A. , Lambert M. , Vanasse M. , Gaudet D. , Rouleau G.A. , Brais B.
      Neurology64:1762-1767(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HSAN2A
    14. 14.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2002 AND SER-2032;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    16. 16.
      "Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II."
      Shekarabi M. , Girard N. , Riviere J.B. , Dion P. , Houle M. , Toulouse A. , Lafreniere R.G. , Vercauteren F. , Hince P. , Laganiere J. , Rochefort D. , Faivre L. , Samuels M. , Rouleau G.A.
      J. Clin. Invest.118:2496-2505(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 4 AND 5);INVOLVEMENT IN HSAN2A
    17. 17.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    18. 18.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-1261; SER-2011; SER-2012; SER-2027; SER-2029 AND SER-2032;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    19. 19.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    20. 20.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1978;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    21. 21.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-1261; SER-1978; SER-2032 AND SER-2121;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    22. 22.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    23. 23.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2027; SER-2029 AND SER-2032;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    24. 24.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION BY KLHL2
    25. 25.
      "The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction."
      Ohta A. , Schumacher F.R. , Mehellou Y. , Johnson C. , Knebel A. , Macartney T.J. , Wood N.T. , Alessi D.R. , Kurz T.
      Biochem. J.451:111-122(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KLHL3
    26. 26.
      "Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4."
      Shibata S. , Zhang J. , Puthumana J. , Stone K.L. , Lifton R.P.
      Proc. Natl. Acad. Sci. U.S.A.110:7838-7843(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;INTERACTION WITH KLHL3
    27. 27.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLY-1199 AND GLU-1799
    28. 28.
      "Patterns of somatic mutation in human cancer genomes."
      Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
      Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] THR-141; VAL-149; GLN-419; THR-509; GLY-527; ILE-665; ALA-674; ARG-823; VAL-1546; GLU-1799; ILE-1808; LEU-1823; HIS-1957; CYS-2190; LEU-2362 AND TRP-2380
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter