WRN ELISA Kit for Human(Homo sapiens) | EIAab.comWRN ELISA Kit for Human(Homo sapiens)

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Index > Protein center > WRN(Gene name) > Human

WRN (Gene name),

Werner syndrome ATP-dependent helicase (Protein name ), WRN_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WRN(RECQ3;RECQL2);

Protein name:

Werner syndrome ATP-dependent helicase;

Alternative:

3.1.-.-;Exonuclease WRN);DNA helicase, RecQ-like type 3(RecQ3);RecQ protein-like 2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer, and homooligomer. May exist as homodimer, homotrimer, homotetramer and/or homohexamer. Homotetramer, or homohexamer, when bound to DNA. Interacts via its N-terminal domain with WRNIP1 (By similarity). Interacts with EXO1, PCNA and SUPV3L1.

Function:

Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions. May play an important role in the dissociation of joint DNA molecules that can arise as products of homologous recombination, at stalled replication forks or during DNA repair. Alleviates stalling of DNA polymerases at the site of DNA lesions. Important for genomic integrity. Plays a role in the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A.

Subcellular Location:

Nucleus nucleolus Nucleus

Protein Attributes:

Sequence length:

1432

Sequence:

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1150:

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1250:

1300:

1350:

1400:

1432:

AERKRRLPVW | FAKGSDTSKK | LMDKTKRGGL | FS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q14191

KEGG:

hsa:7486

Pfam:

PF00270

STRING:

9606.ENSP00000298139

SMR:

Q14191

MIM:

114500

UniGene:

Hs.632050

Uniprot:

Q14191

FOR

ELISA Kit for Human Werner syndrome ATP-dependent helicase

CLIA Kit for Human Werner syndrome ATP-dependent helicase

Polyclonal Antibody for Human Werner syndrome ATP-dependent helicase

Monoclonal Antibody for Human Werner syndrome ATP-dependent helicase

Protein for Human Werner syndrome ATP-dependent helicase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Positional cloning of the Werner's syndrome gene."
Yu C.-E. , Oshima J. , Fu Y.-H. , Wijsman E.M. , Hisama F. , Alisch R. , Matthews S. , Nakura J. , Miki T. , Ouais S. , Martin G.M. , Mulligan J. , Schellenberg G.D.
Science272:258-262(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT PHE-1074
2.

"Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer."
Agrelo R. , Cheng W.H. , Setien F. , Ropero S. , Espada J. , Fraga M.F. , Herranz M. , Paz M.F. , Sanchez-Cespedes M. , Artiga M.J. , Guerrero D. , Castells A. , von Kobbe C. , Bohr V.A. , Esteller M.
Proc. Natl. Acad. Sci. U.S.A.103:8822-8827(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-1074
3.

"Genomic structure of the human Werner's gene and cloning of the mouse homolog."
Paeper B.W. , Gayle M. , Brady W. , Swartz A. , Gillett L.A. , Alisch R.S. , Mulligan J. , Galas D. , Fu Y.-H.
Submitted (1999-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-1074
4.

NIEHS SNPs program
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ILE-114; LYS-343; ILE-387; SER-533; CYS-612; PHE-708; CYS-834; SER-912; LEU-1079; ALA-1133; ILE-1339 AND ARG-1367
5.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"Nucleolar localization of the Werner syndrome protein in human cells."
Marciniak R.A. , Lombard D.B. , Johnson F.B. , Guarente L.
Proc. Natl. Acad. Sci. U.S.A.95:6887-6892(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
7.

"Evolution of the RECQ family of helicases: a Drosophila homolog, Dmblm, is similar to the human Bloom syndrome gene."
Kusano K. , Berres M.E. , Engels W.R.
Genetics151:1027-1039(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REPEATS
8.

"A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities."
Xue Y. , Ratcliff G.C. , Wang H. , Davis-Searles P.R. , Gray M.D. , Erie D.A. , Redinbo M.R.
Biochemistry41:2901-2912(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF GLU-84;FUNCTION AS AN EXONUCLEASE;DNA-BINDING;INTERACTION WITH PCNA;SUBUNIT
9.

"Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation."
Karmakar P. , Piotrowski J. , Brosh R.M. Jr. , Sommers J.A. , Miller S.P. , Cheng W.H. , Snowden C.M. , Ramsden D.A. , Bohr V.A.
J. Biol. Chem.277:18291-18302(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
10.

"The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein."
Sharma S. , Sommers J.A. , Driscoll H.C. , Uzdilla L.A. , Wilson T.M. , Brosh R.M. Jr.
J. Biol. Chem.278:23487-23496(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EXO1
11.

"Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality."
Pereira M. , Mason P. , Szczesny R.J. , Maddukuri L. , Dziwura S. , Jedrzejczak R. , Paul E. , Wojcik A. , Dybczynska L. , Tudek B. , Bartnik E. , Klysik J. , Bohr V.A. , Stepien P.P.
Mech. Ageing Dev.128:609-617(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SUPV3L1
12.

"Werner syndrome protein interacts functionally with translesion DNA polymerases."
Kamath-Loeb A.S. , Lan L. , Nakajima S. , Yasui A. , Loeb L.A.
Proc. Natl. Acad. Sci. U.S.A.104:10394-10399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
13.

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
14.

"The Werner syndrome protein binds replication fork and Holliday junction DNAs as an oligomer."
Compton S.A. , Tolun G. , Kamath-Loeb A.S. , Loeb L.A. , Griffith J.D.
J. Biol. Chem.283:24478-24483(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;DNA-BINDING
15.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-440 AND SER-467;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.

"WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts."
Zecevic A. , Menard H. , Gurel V. , Hagan E. , DeCaro R. , Zhitkovich A.
Cell Cycle8:2769-2778(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
18.

"The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation."
Opresko P.L. , Sowd G. , Wang H.
PLoS ONE4:E4825-E4825(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
19.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-426; SER-440; SER-453 AND SER-467;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
20.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"Promyelocytic leukemia protein interacts with werner syndrome helicase and regulates double-strand break repair in gamma-irradiation-induced DNA damage responses."
Liu J. , Song Y. , Qian J. , Liu B. , Dong Y. , Tian B. , Sun Z.
Biochemistry (Mosc.)76:550-554(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PML
22.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1133;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
24.

"Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein."
Hu J.S. , Feng H. , Zeng W. , Lin G.X. , Xi X.G.
Proc. Natl. Acad. Sci. U.S.A.102:18379-18384(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 949-1092
25.

"WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing."
Perry J.J. , Yannone S.M. , Holden L.G. , Hitomi C. , Asaithamby A. , Han S. , Cooper P.K. , Chen D.J. , Tainer J.A.
Nat. Struct. Mol. Biol.13:414-422(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 38-236 IN COMPLEXES WITH MAGNESIUM; MANGANESE; EUROPIUM AND GMP;PARTIAL PROTEIN SEQUENCE;IDENTIFICATION BY MASS SPECTROMETRY;CATALYTIC ACTIVITY;COFACTOR;MUTAGENESIS OF GLU-84; TRP-145 AND TYR-212;CHARACTERIZATION OF VARIANTS ILE-114 AND PRO-172
26.

"WRN mutations in Werner syndrome."
Moser M.J. , Oshima J. , Monnat R.J. Jr.
Hum. Mutat.13:271-279(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
27.

"Solution structure of the helicase and RNase D C-terminal domain in Werner syndrome ATP-dependent helicase."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-09) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1140-1239
28.

"Crystal structure of the HRDC domain of human Werner syndrome protein, WRN."
Kitano K. , Yoshihara N. , Hakoshima T.
J. Biol. Chem.282:2717-2728(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 1142-1242;PARTIAL PROTEIN SEQUENCE;IDENTIFICATION BY MASS SPECTROMETRY;CIRCULAR DICHROISM
29.

"Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN."
Kitano K. , Kim S.Y. , Hakoshima T.
Structure18:177-187(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 949-1079 IN COMPLEX WITH DOUBLE-STRANDED DNA;INTERACTION WITH DNA;MUTAGENESIS OF ARG-987; SER-989; ARG-993; PHE-1037 AND MET-1038
30.

"Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population."
Ye L. , Miki T. , Nakura J. , Oshima J. , Kamino K. , Rakugi H. , Ikegami H. , Higaki J. , Edland S.D. , Martin G.M. , Ogihara T.
Am. J. Med. Genet.68:494-498(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARG-1367
31.

Ye L. , Miki T. , Nakura J. , Oshima J. , Kamino K. , Rakugi H. , Ikegami H. , Higaki J. , Edland S.D. , Martin G.M. , Ogihara T.
Am. J. Med. Genet.70:103-103(1997)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
32.

"Werner syndrome: characterization of mutations in the WRN gene in an affected family."
Meisslitzer C. , Ruppitsch W. , Weirich-Schwaiger H. , Weirich H.G. , Jabkowsky J. , Klein G. , Schweiger M. , Hirsch-Kauffmann M.
Eur. J. Hum. Genet.5:364-370(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-387 AND PHE-1074
33.

"The 1396del A mutation and a missense mutation or a rare polymorphism of the WRN gene detected in a French Werner family with a severe phenotype and a case of an unusual vulvar cancer."
Vidal V. , Bay J.-O. , Champomier F. , Grancho M. , Beauville L. , Glowaczower C. , Lemery D. , Ferrara M. , Bignon Y.-J.
Hum. Mutat.11:413-414(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ILE-387
34.

"Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians."
Castro E. , Ogburn C.E. , Hunt K.E. , Tilvis R. , Louhija J. , Penttinen R. , Erkkola R. , Panduro A. , Riestra R. , Piussan C. , Deeb S.S. , Wang L. , Edland S.D. , Martin G.M. , Oshima J.
Am. J. Med. Genet.82:399-403(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ALA-324 AND ARG-1367
35.

"The Werner syndrome gene and global sequence variation."
Passarino G. , Shen P. , Van Kirk J.B. , Lin A.A. , De Benedictis G. , Cavalli-Sforza L.L. , Oefner P.J. , Underhill P.A.
Genomics71:118-122(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARG-32; ILE-114; PRO-172; LYS-240; TRP-383; ILE-387; LEU-724; PHE-1074; GLU-1269 AND ARG-1367
36.

"The spectrum of WRN mutations in Werner syndrome patients."
Huang S. , Lee L. , Hanson N.B. , Lenaerts C. , Hoehn H. , Poot M. , Rubin C.D. , Chen D.-F. , Yang C.-C. , Juch H. , Dorn T. , Spiegel R. , Oral E.A. , Abid M. , Battisti C. , Lucci-Cordisco E. , Neri G. , Steed E.H. , more...
Hum. Mutat.27:558-567(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS WRN ASN-125 AND GLU-135
37.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-92
38.

"DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome."
Ley T.J. , Mardis E.R. , Ding L. , Fulton B. , McLellan M.D. , Chen K. , Dooling D. , Dunford-Shore B.H. , McGrath S. , Hickenbotham M. , Cook L. , Abbott R. , Larson D.E. , Koboldt D.C. , Pohl C. , Smith S. , Hawkins A. , Abbott S. , more...
Nature456:66-72(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LEU-1141

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