WT1 ELISA Kit for Human(Homo sapiens) | EIAab.comWT1 ELISA Kit for Human(Homo sapiens)

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WT1 (Gene name),

Wilms tumor protein (Protein name ), WT1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WT1;

Protein name:

Wilms tumor protein;

Alternative:

WT33;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts with WTIP. Interacts with actively translating polysomes. Detected in nuclear ribonucleoprotein (mRNP) particles. Interacts with HNRNPU via the zinc-finger region. Interacts with U2AF2. Interacts with CITED2 (By similarity). Interacts with ZNF224 via the zinc-finger region. Interacts with WTAP and SRY. Interacts with FAM123B/WTX. Interacts with RBM4.

Function:

Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Subcellular Location:

Isoform 4 Nucleus nucleoplasm

Protein Attributes:

Sequence length:

449

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

449:

HTRTHTGKTS | EKPFSCRWPS | CQKKFARSDE | LVRHHNMHQR | NMTKLQLAL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P19544

MIM:

136680

KEGG:

hsa:7490

Pfam:

PF02165

String:

P19544

UniGene:

Hs.591980

Uniprot:

P19544

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ELISA Kit for Human Wilms tumor protein

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E11563h

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96T

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ELISA Kit for Human Wilms tumor protein

Cat.:

E11563m

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96T

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ELISA Kit for Human Wilms tumor protein

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ELISA Kit for Human Wilms tumor protein

Cat.:

E11563r

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Packing:

96T

CLIA Kit for Human Wilms tumor protein

Cat.:

U11563h

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Packing:

96T

CLIA Kit for Human Wilms tumor protein

MSDS:

Please sign in first.

CLIA Kit for Human Wilms tumor protein

Cat.:

U11563m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Wilms tumor protein

Cat.:

U11563r

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96T

Polyclonal Antibody for Human Wilms tumor protein

Cat.:

P11563Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Wilms tumor protein

Monoclonal Antibody for Human Wilms tumor protein

Protein for Human Wilms tumor protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping."
Gessler M. , Poustka A. , Cavenee W. , Neve R.L. , Orkin S.H. , Bruns G.A.P.
Nature343:774-778(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7)
tissue: Fetal kidney.
2.

"Alternative splicing and genomic structure of the Wilms tumor gene WT1."
Haber D.A. , Sohn R.L. , Buckler A.J. , Pelletier J. , Call K.M. , Housman D.E.
Proc. Natl. Acad. Sci. U.S.A.88:9618-9622(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORMS 1; 2; 3 AND 4)
tissue: Placenta.
3.

"The genomic organization and expression of the WT1 gene."
Gessler M. , Konig A. , Bruns G.A.P.
Genomics12:807-813(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 4)
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 9)
tissue: Placenta.
tissue: Testis.
5.

NIEHS SNPs program
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 1)
6.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6)
tissue: Testis.
9.

"Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus."
Call K.M. , Glaser T. , Ito C.Y. , Buckler A.J. , Pelletier J. , Haber D.A. , Rose E.A. , Kral A. , Yeger H. , Lewis W.H. , Jones C. , Housman D.E.
Cell60:509-520(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 85-449 (ISOFORM 2)
10.

"High affinity binding sites for the Wilms' tumour suppressor protein WT1."
Hamilton T.B. , Barilla K.C. , Romaniuk P.J.
Nucleic Acids Res.23:277-284(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 301-449 (ISOFORMS 2/4/6)
tissue: Fetal kidney.
11.

"Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome."
Pelletier J. , Bruening W. , Kashtan C.E. , Mauer S.M. , Manivel J.C. , Striegel J.E. , Houghton D.C. , Junien C. , Habib R. , Fouser L. , Fine R.N. , Silverman B.L. , Haber D.A. , Housman D.E.
Cell67:437-447(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 385-405;VARIANTS DDS
12.

"Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development."
Bruening W. , Bardeesy N. , Silverman B.L. , Cohn R.A. , Machin G.A. , Aronson A.J. , Housman D. , Pelletier J.
Nat. Genet.1:144-148(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 385-405;VARIANTS DDS TYR-330; PRO-394 AND TRP-394
13.

"Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development."
Buckler A.J. , Pelletier J. , Haber D.A. , Glaser T. , Housman D.E.
Mol. Cell. Biol.11:1707-1712(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF START CODON;ALTERNATIVE SPLICING
14.

"RNA editing in the Wilms' tumor susceptibility gene, WT1."
Sharma P.M. , Bowman M. , Madden S.L. , Rauscher F.J. III , Sukumar S.
Genes Dev.8:720-731(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RNA EDITING OF POSITION 281
15.

"A non-AUG translational initiation event generates novel WT1 isoforms."
Bruening W. , Pelletier J.
J. Biol. Chem.271:8646-8654(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE INITIATION;ALTERNATIVE SPLICING (ISOFORMS 7 AND 8)
16.

"Identification of WTAP, a novel Wilms' tumour 1-associating protein."
Little N.A. , Hastie N.D. , Davies R.C.
Hum. Mol. Genet.9:2231-2239(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH WTAP
17.

"Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor."
Lee T.H. , Lwu S. , Kim J. , Pelletier J.
J. Biol. Chem.277:44826-44837(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZNF224
18.

"Transcriptional activity of testis-determining factor SRY is modulated by the Wilms' tumor 1 gene product, WT1."
Matsuzawa-Watanabe Y. , Inoue J. , Semba K.
Oncogene22:7900-7904(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRY
19.

"WT1: a novel tumor suppressor gene inactivated in Wilms' tumor."
Haber D.A. , Buckler A.J.
New Biol.4:97-106(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
20.

"The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor."
Rauscher F.J. III
FASEB J.7:896-903(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
21.

"WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour."
Pelletier J. , Bruening W. , Li F.P. , Haber D.A. , Glaser T. , Housman D.E.
Nature353:431-434(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN WILMS TUMOR
22.

"A tumor suppressor and oncogene: the WT1 story."
Yang L. , Han Y. , Suarez Saiz F. , Minden M.D.
Leukemia21:868-876(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
23.

"SUMO-1 modification of the Wilms' tumor suppressor WT1."
Smolen G.A. , Vassileva M.T. , Wells J. , Matunis M.J. , Haber D.A.
Cancer Res.64:7846-7851(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-73 AND LYS-177;SUMOYLATION AT LYS-73 AND LYS-177
24.

"WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo."
Markus M.A. , Heinrich B. , Raitskin O. , Adams D.J. , Mangs H. , Goy C. , Ladomery M. , Sperling R. , Stamm S. , Morris B.J.
Exp. Cell Res.312:3379-3388(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RBM4;SUBCELLULAR LOCATION
25.

"Contribution of individual amino acids to the RNA binding activity of the Wilms' tumor suppressor protein WT1."
Weiss T.C. , Romaniuk P.J.
Biochemistry48:148-155(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF HIS-343; ARG-366; ARG-372; ARG-394 AND HIS-434
26.

"The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity."
Rivera M.N. , Kim W.J. , Wells J. , Stone A. , Burger A. , Coffman E.J. , Zhang J. , Haber D.A.
Proc. Natl. Acad. Sci. U.S.A.106:8338-8343(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AMER1;FUNCTION
27.

"Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity."
Lachenmann M.J. , Ladbury J.E. , Dong J. , Huang K. , Carey P. , Weiss M.A.
Biochemistry43:13910-13925(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 381-407 IN COMPLEX WITH ZINC IONS
28.

"Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA."
Stoll R. , Lee B.M. , Debler E.W. , Laity J.H. , Wilson I.A. , Dyson H.J. , Wright P.E.
J. Mol. Biol.372:1227-1245(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 318-438 IN COMPLEX WITH DNA AND ZINC IONS (ISOFORM 4);X-RAY CRYSTALLOGRAPHY (3.15 ANGSTROMS) OF 318-438 IN COMPLEX WITH DNA AND ZINC IONS
29.

"Zinc finger point mutations within the WT1 gene in Wilms tumor patients."
Little M.H. , Prosser J. , Condie A. , Smith P.J. , van Heyningen V. , Hastie N.D.
Proc. Natl. Acad. Sci. U.S.A.89:4791-4795(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT WT1 CYS-366
30.

"Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome."
Baird P.N. , Santos A. , Groves N. , Jadresic L. , Cowell J.K.
Hum. Mol. Genet.1:301-305(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS
31.

"Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion."
Little M.H. , Williamson K.A. , Mannens M. , Kelsey A. , Gosden C. , Hastie N.D. , van Heyningen V.
Hum. Mol. Genet.2:259-264(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS
32.

"A novel zinc finger mutation in a patient with Denys-Drash syndrome."
Baird P.N. , Cowell J.K.
Hum. Mol. Genet.2:2193-2194(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS TYR-401
33.

"Molecular analysis of two Japanese cases of Denys-Drash syndrome."
Tsuda M. , Sakiyama T. , Kitagawa T. , Watanabe S. , Watanabe T. , Takahashi S. , Kawaguchi H. , Ito K.
J. Inherit. Metab. Dis.16:876-880(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS TRP-394 AND PRO-398
34.

"Mutational screening of the Wilms's tumour gene, WT1, in males with genital abnormalities."
Clarkson P.A. , Davies H.R. , Williams D.M. , Chaudhary R. , Hughes I.A. , Patterson M.N.
J. Med. Genet.30:767-772(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS TYR-360 AND TRP-394
35.

"The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma."
Park S. , Schalling M. , Bernard A. , Maheswaran S. , Shipley G.C. , Roberts D. , Fletcher J. , Shipman R. , Rheinwald J. , Demetri G. , Griffin J. , Minden M. , Housman D.E. , Haber D.A.
Nat. Genet.4:415-420(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLY-273;INVOLVEMENT IN MESOM
36.

"WT1 mutations in patients with Denys-Drash syndrome: a novel mutation in exon 8 and paternal allele origin."
Nordenskjold A. , Friedman E. , Anvret M.
Hum. Genet.93:115-120(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS ARG-377
37.

"A newly identified exonic mutation of the WT1 gene in a patient with Denys-Drash syndrome."
Tsuda M. , Sakiyama T. , Owada M. , Chiba Y.
Acta Paediatr. Jpn. Overseas Ed.38:265-266(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS LEU-366
38.

"A novel mutation H373Y in the Wilms' tumor suppressor gene, WT1, associated with Denys-Drash syndrome."
Ghahremani M. , Chan C.B. , Bistritzer T. , Aladjem M.M. , Tieder M. , Pelletier J.
Hum. Hered.46:336-338(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS TYR-373
39.

"Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology."
Schumacher V. , Schneider S. , Figge A. , Wildhardt G. , Harms D. , Schmidt D. , Weirich A. , Ludwig R. , Royer-Pokora B.
Proc. Natl. Acad. Sci. U.S.A.94:3972-3977(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS WT1 SER-181 AND ALA-253
40.

"Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database."
Jeanpierre C. , Denamur E. , Henry I. , Cabanis M.-O. , Luce S. , Cecille A. , Elion J. , Peuchmaur M. , Loirat C. , Niaudet P. , Gubler M.-C. , Junien C.
Am. J. Hum. Genet.62:824-833(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NPHS4 TYR-377; LEU-383 AND ASN-396;VARIANTS DDS CYS-366; GLN-394; TRP-394 AND PRO-398;VARIANT WT1 ASN-223
41.

"Do intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome?"
Kikuchi H. , Takata A. , Akasaka Y. , Fukuzawa R. , Yoneyama H. , Kurosawa Y. , Honda M. , Kamiyama Y. , Hata J.
J. Med. Genet.35:45-48(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS TYR-355; HIS-366 AND ARG-385
42.

"Spectrum of early onset nephrotic syndrome associated with WT1 missense mutations."
Schumacher V. , Schaerer K. , Wuehl E. , Altrogge H. , Bonzel K.-E. , Guschmann M. , Neuhaus T.J. , Pollastro R.M. , Kuwertz-Broeking E. , Bulla M. , Tondera A.-M. , Mundel P. , Helmchen U. , Waldherr R. , Weirich A. , Royer-Pokora B.
Kidney Int.53:1594-1600(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NPHS4 LEU-364; HIS-366; CYS-379; ARG-385; GLN-394; TRP-394 AND ASN-396
43.

"Exon 9 mutations in the WT1 gene, without influencing KTS splice isoforms, are also responsible for Frasier syndrome."
Kohsaka T. , Tagawa M. , Takekoshi Y. , Yanagisawa H. , Tadokoro K. , Yamada M.
Hum. Mutat.14:466-470(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FS LEU-392
44.

"Novel WT1 exon 9 mutation (D396Y) in a patient with early onset Denys Drash syndrome."
Little M. , Carman G. , Donaldson E.
Hum. Mutat.15:389-389(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS TYR-396
45.

"Constitutional WT1 correlate with clinical features in children with progressive nephropathy."
Takata A. , Kikuchi H. , Fukuzawa R. , Ito S. , Honda M. , Hata J.
J. Med. Genet.37:698-701(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DDS ARG-342; TYR-355; HIS-366; ARG-385; PHE-388; TRP-394 AND ASN-396;VARIANT NPHS4 GLN-312
46.

"A novel missense mutation of the WT1 gene causing Denys-Drash syndrome with exceptionally mild renal manifestations."
Ohta S. , Ozawa T. , Izumino K. , Sakuragawa N. , Fuse H.
J. Urol.163:1857-1858(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS PRO-369
47.

"Novel WT1 mutation (C388Y) in a female child with Denys-Drash syndrome."
Swiatecka-Urban A. , Mokrzycki M.H. , Kaskel F. , Da Silva F. , Denamur E.
Pediatr. Nephrol.16:627-630(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS TYR-388
48.

"Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development."
Royer-Pokora B. , Beier M. , Henzler M. , Alam R. , Schumacher V. , Weirich A. , Huff V.
Am. J. Med. Genet. A127:249-257(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS WT1 SER-181; GLY-355; CYS-366; HIS-366; GLN-373; TRP-394 AND LEU-394
49.

"Mutation analysis of five candidate genes in Chinese patients with hypospadias."
Wang Y. , Li Q. , Xu J. , Liu Q. , Wang W. , Lin Y. , Ma F. , Chen T. , Li S. , Shen Y.
Eur. J. Hum. Genet.12:706-712(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-131
50.

"Prevalence of WT1 mutations in a large cohort of patients with steroid-resistant and steroid-sensitive nephrotic syndrome."
Members of the APN study group , Ruf R.G. , Schultheiss M. , Lichtenberger A. , Karle S.M. , Zalewski I. , Mucha B. , Everding A.S. , Neuhaus T. , Patzer L. , Plank C. , Haas J.P. , Ozaltin F. , Imm A. , Fuchshuber A. , Bakkaloglu A. , Hildebrandt F.
Kidney Int.66:564-570(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NPHS4 ARG-388 AND PRO-397
51.

"A novel mutation of WT1 exon 9 in a patient with Denys-Drash syndrome and pyloric stenosis."
Hu M. , Craig J. , Howard N. , Kan A. , Chaitow J. , Little D. , Alexander S.I.
Pediatr. Nephrol.19:1160-1163(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DDS ARG-405
52.

"WT1 mutations in Meacham syndrome suggest a coelomic mesothelial origin of the cardiac and diaphragmatic malformations."
Suri M. , Kelehan P. , O'neill D. , Vadeyar S. , Grant J. , Ahmed S.F. , Tolmie J. , McCann E. , Lam W. , Smith S. , FitzPatrick D. , Hastie N.D. , Reardon W.
Am. J. Med. Genet. A143:2312-2320(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MEACHS CYS-366 AND TRP-394

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