XYLT2 ELISA Kit for Human(Homo sapiens) | EIAab.comXYLT2 ELISA Kit for Human(Homo sapiens) | EIAab.com

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XYLT2 (Gene name),

Xylosyltransferase 2 (Protein name ), XYLT2_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

XYLT2(UNQ3058/PRO9878;XT2);

Protein name:

Xylosyltransferase 2;

Alternative:

Xylosyltransferase II(XT-II;XylT-II);Peptide O-xylosyltransferase 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass type II membrane protein Golgi apparatus membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

865

Sequence:

50:

MVASARVQKL | VRRYKLAIAT | ALAILLLQGL | VVWSFSGLEE | DEAGEKGRQR |

100:

KPRPLDPGEG | SKDTDSSAGR | RGSTGRRHGR | WRGRAESPGV | PVAKVVRAVT |

150:

SRQRASRRVP | PAPPPEAPGR | QNLSGAAAGE | ALVGAAGFPP | HGDTGSVEGA |

200:

PQPTDNGFTP | KCEIVGKDAL | SALARASTKQ | CQQEIANVVC | LHQAGSLMPK |

250:

AVPRHCQLTG | KMSPGIQWDE | SQAQQPMDGP | PVRIAYMLVV | HGRAIRQLKR |

300:

LLKAVYHEQH | FFYIHVDKRS | DYLHREVVEL | AQGYDNVRVT | PWRMVTIWGG |

350:

ASLLRMYLRS | MRDLLEVPGW | AWDFFINLSA | TDYPTRTNEE | LVAFLSKNRD |

400:

KNFLKSHGRD | NSRFIKKQGL | DRLFHECDSH | MWRLGERQIP | AGIVVDGGSD |

450:

WFVLTRSFVE | YVVYTDDPLV | AQLRQFYTYT | LLPAESFFHT | VLENSLACET |

500:

LVDNNLRVTN | WNRKLGCKCQ | YKHIVDWCGC | SPNDFKPQDF | LRLQQVSRPT |

550:

FFARKFESTV | NQEVLEILDF | HLYGSYPPGT | PALKAYWENT | YDAADGPSGL |

600:

SDVMLTAYTA | FARLSLHHAA | TAAPPMGTPL | CRFEPRGLPS | SVHLYFYDDH |

650:

FQGYLVTQAV | QPSAQGPAET | LEMWLMPQGS | LKLLGRSDQA | SRLQSLEVGT |

700:

DWDPKERLFR | NFGGLLGPLD | EPVAVQRWAR | GPNLTATVVW | IDPTYVVATS |

750:

YDITVDTETE | VTQYKPPLSR | PLRPGPWTVR | LLQFWEPLGE | TRFLVLPLTF |

800:

NRKLPLRKDD | ASWLHAGPPH | NEYMEQSFQG | LSSILNLPQP | ELAEEAAQRH |

850:

TQLTGPALEA | WTDRELSSFW | SVAGLCAIGP | SPCPSLEPCR | LTSWSSLSPD |

865:

PKSELGPVKA | DGRLR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000017003

UniGene:

KEGG:

SMR:

MIM:

Pfam:

String:

Uniprot:

FOR

ELISA Kit for Human Xylosyltransferase 2

ELISA Kit for Human Xylosyltransferase 2

ELISA Kit for Human Xylosyltransferase 2

ELISA Kit for Human Xylosyltransferase 2

ELISA Kit for Human Xylosyltransferase 2

CLIA Kit for Human Xylosyltransferase 2

CLIA Kit for Human Xylosyltransferase 2

CLIA Kit for Human Xylosyltransferase 2

CLIA Kit for Human Xylosyltransferase 2

CLIA Kit for Human Xylosyltransferase 2

Polyclonal Antibody for Human Xylosyltransferase 2

Polyclonal Antibody for Human Xylosyltransferase 2

Polyclonal Antibody for Human Xylosyltransferase 2

Polyclonal Antibody for Human Xylosyltransferase 2

Polyclonal Antibody for Human Xylosyltransferase 2

Monoclonal Antibody for Human Xylosyltransferase 2

Monoclonal Antibody for Human Xylosyltransferase 2

Monoclonal Antibody for Human Xylosyltransferase 2

Monoclonal Antibody for Human Xylosyltransferase 2

Monoclonal Antibody for Human Xylosyltransferase 2

Protein for Human Xylosyltransferase 2

Protein for Human Xylosyltransferase 2

Protein for Human Xylosyltransferase 2

Protein for Human Xylosyltransferase 2

Protein for Human Xylosyltransferase 2

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase and its first isoform XT-II."
Goetting C. , Kuhn J. , Zahn R. , Brinkmann T. , Kleesiek K.
J. Mol. Biol.304:517-528(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-305;TISSUE SPECIFICITY
tissue: Chondrosarcoma.
2.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-305
tissue: Pancreas.
4.

"Polymorphisms in the xylosyltransferase genes cause higher serum XT-I activity in patients with pseudoxanthoma elasticum (PXE) and are involved in a severe disease course."
Schon S. , Schulz V. , Prante C. , Hendig D. , Szliska C. , Kuhn J. , Kleesiek K. , Gotting C.
J. Med. Genet.43:745-749(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASN-56; LEU-115; THR-305; LEU-418 AND ARG-801

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