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Index > Protein center > Yaf2(Gene name) > Mouse
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  • Yaf2 (Gene name),
  • YY1-associated factor 2 (Protein name ),  YAF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Yaf2;
    Protein name:
    YY1-associated factor 2;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MYC, MYCN, RNF2/RING1B and YY1. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2.
    Function:
    Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    179
    Sequence:
    50:
    MGDKKSPTRP | KRQPKPASDE | GYWDCSVCTF | RNSAEAFKCM | MCDVRKGTST | 
    100:
    RKPRPVSQLV | AQQVTQQFVP | PTQSKKEKKD | RVEKDKSEKE | AASKKNCHKK | 
    150:
    TRPRLKNVDR | SSAQHLEVTV | GDLTVIITDF | KEKAKSAPAS | SAAGDQHSQG | 
    179:
    SCSSDSTERG | VSRSSSPRGE | ASSLNGESH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse YY1-associated factor 2
    ELISA Kit for Mouse YY1-associated factor 2
    CLIA Kit for Mouse YY1-associated factor 2
    CLIA Kit for Mouse YY1-associated factor 2
    Polyclonal Antibody for Mouse YY1-associated factor 2
    Polyclonal Antibody for Mouse YY1-associated factor 2
    Monoclonal Antibody for Mouse YY1-associated factor 2
    Monoclonal Antibody for Mouse YY1-associated factor 2
    Protein for Mouse YY1-associated factor 2
    Protein for Mouse YY1-associated factor 2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The mouse YAF2 gene generates two distinct transcripts and is expressed in pre- and postimplantation embryos."
      Kaneko T. , Miyagishima H. , Hasegawa T. , Mizutani-Koseki Y. , Isono K. , Koseki H.
      Gene315:183-192(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INTERACTION WITH RNF2
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Liver.
      tissue: Sympathetic ganglion.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Mammary gland.
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