ZEB2 ELISA Kit for Human(Homo sapiens) | EIAab.comZEB2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ZEB2(Gene name) > Human

ZEB2 (Gene name),

Zinc finger E-box-binding homeobox 2 (Protein name ), ZEB2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ZEB2(HRIHFB2411;KIAA0569;SIP1;ZFHX1B;ZFX1B);

Protein name:

Zinc finger E-box-binding homeobox 2;

Alternative:

Zinc finger homeobox protein 1b;Smad-interacting protein 1(SMADIP1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds activated SMAD1, activated SMAD2 and activated SMAD3; binding with SMAD4 is not detected (By similarity). Interacts with CBX4 and CTBP1.

Function:

Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1214

Sequence:

50:

100:

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1150:

1200:

1214:

TKSDHEEDNM | EDGM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O60315

MIM:

235730

SMR:

O60315

UniGene:

Hs.34871

STRING:

9606.ENSP00000302501

KEGG:

hsa:9839

Pfam:

PF05605

Pfam:

PF00096

Uniprot:

O60315

FOR

ELISA Kit for Human Zinc finger E-box-binding homeobox 2

Cat.:

E14971h

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Manual:

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Packing:

96T

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ELISA Kit for Human Zinc finger E-box-binding homeobox 2

Cat.:

E14971m

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger E-box-binding homeobox 2

Cat.:

U14971m

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger E-box-binding homeobox 2

Cat.:

U14971h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Zinc finger E-box-binding homeobox 2

Monoclonal Antibody for Human Zinc finger E-box-binding homeobox 2

Protein for Human Zinc finger E-box-binding homeobox 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Loss-of-function mutations in SIP1 Smad interacting protein 1 result in a syndromic Hirschsprung disease."
Cacheux V. , Dastot-Le Moal F. , Kaeaeriaeinen H. , Bondurand N. , Rintala R. , Boissier B. , Wilson M. , Mowat D. , Goossens M.
Hum. Mol. Genet.10:1503-1510(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];INVOLVEMENT IN MOWS
2.

"Mutations in SIP1, encoding Smad interacting protein 1, cause a form of Hirschsprung disease."
Wakamatsu N. , Yamada Y. , Yamada K. , Ono T. , Nomura N. , Taniguchi H. , Kitoh H. , Mutoh N. , Yamanaka T. , Mushiake K. , Kato K. , Sonta S. , Nagaya M.
Nat. Genet.27:369-370(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
Nagase T. , Ishikawa K. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.5:31-39(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Brain.
5.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"Selection system for genes encoding nuclear-targeted proteins."
Ueki N. , Oda T. , Kondo M. , Yano K. , Noguchi T. , Muramatsu M.-A.
Nat. Biotechnol.16:1338-1342(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1161-1214 (ISOFORM 1);SUBCELLULAR LOCATION
tissue: Fetal brain.
8.

"Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin."
Long J. , Zuo D. , Park M.
J. Biol. Chem.280:35477-35489(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUMOYLATION AT LYS-391 AND LYS-866;INTERACTION WITH CBX4 AND CTBP1;SUBCELLULAR LOCATION
9.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-377;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Solution structure of the homeobox domain of zinc finger homeobox protein 1B (SMAD interacting protein 1)."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-12) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 647-705
11.

"Late infantile Hirschsprung disease-mental retardation syndrome with a 3-bp deletion in ZFHX1B."
Yoneda M. , Fujita T. , Yamada Y. , Yamada K. , Fujii A. , Inagaki T. , Nakagawa H. , Shimada A. , Kishikawa M. , Nagaya M. , Azuma T. , Kuriyama M. , Wakamatsu N.
Neurology59:1637-1640(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MOWS ASN-99 DEL
12.

"Ocular coloboma and high myopia with Hirschsprung disease associated with a novel ZFHX1B missense mutation and trisomy 21."
Gregory-Evans C.Y. , Vieira H. , Dalton R. , Adams G.G.W. , Salt A. , Gregory-Evans K.
Am. J. Med. Genet. A131:86-90(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MOWS GLY-953
13.

"A missense mutation in the ZFHX1B gene associated with an atypical Mowat-Wilson syndrome phenotype."
Heinritz W. , Zweier C. , Froster U.G. , Strenge S. , Kujat A. , Syrbe S. , Rauch A. , Schuster V.
Am. J. Med. Genet. A140:1223-1227(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MOWS ARG-1119
14.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASN-983

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