Gene name:
ZFP57 (C6orf40;ZNF698) ;
Protein name:
Zinc finger protein 57 homolog (Zfp-57) ;
Alternative:
Zinc finger protein 698 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Subcellular Location:
Nucleus
Binds various differentially methylated regions (DMR), including the SNRPN DMR.
Protein Attributes:
50:
MAAGEPRSLL | FFQKPVTFED | VAVNFTQEEW | DCLDASQRVL | YQDVMSETFK |
100:
NLTSVARIFL | HKPELITKLE | QEEEQWRETR | VLQASQAGPP | FFCYTCGKCF |
150:
SRRSYLYSHQ | FVHNPKLTNS | CSQCGKLFRS | PKSLSYHRRM | HLGERPFCCT |
200:
LCDKTYCDAS | GLSRHRRVHL | GYRPHSCSVC | GKSFRDQSEL | KRHQKIHQNQ |
250:
EPVDGNQECT | LRIPGTQAEF | QTPIARSQRS | IQGLLDVNHA | PVARSQEPIF |
300:
RTEGPMAQNQ | ASVLKNQAPV | TRTQAPITGT | LCQDARSNSH | PVKPSRLNVF |
350:
CCPHCSLTFS | KKSYLSRHQK | AHLTEPPNYC | FHCSKSFSSF | SRLVRHQQTH |
400:
WKQKSYLCPI | CDLSFGEKEG | LMDHWRGYKG | KDLCQSSHHK | CRVILGQWLG |
450:
FSHDVPTMAG | EEWKHGGDQS | PPRIHTPRRR | GLREKACKGD | KTKEAVSILK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Zfp-57
ELISA Kit for Human Zfp-57
ELISA Kit for Human Zfp-57
CLIA Kit for Human Zfp-57
CLIA Kit for Human Zfp-57
CLIA Kit for Human Zfp-57
Polyclonal Antibody for Human Zfp-57
Polyclonal Antibody for Human Zfp-57
Polyclonal Antibody for Human Zfp-57
Monoclonal Antibody for Human Zfp-57
Monoclonal Antibody for Human Zfp-57
Monoclonal Antibody for Human Zfp-57
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT VAL-284
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS TNDM1 HIS-166; ASN-193 AND ASP-374;FUNCTION