Zinc finger FYVE domain-containing protein 16 (Protein name
), ZFY16_HUMAN from NCBI database.
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General Annotation
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Antigen Annotation
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Predicted Eptitope
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Vaild Sequence
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Gene name:
ZFYVE16(KIAA0305);
Protein name:
Zinc finger FYVE domain-containing protein 16;
Alternative:
Endosome-associated FYVE domain protein;Endofin;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with the C-terminus of TOM1. Does not interact with TOM1L1 or TOM1L2.
Function:
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
Subcellular Location:
Cytoplasm
Early endosome membrane
Peripheral membrane protein
Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate.
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DOMAIN;MUTAGENESIS OF CYS-753;VARIANTS THR-192; THR-598 AND GLY-1055
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS THR-192; THR-598 AND GLY-1055
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS THR-192; THR-598 AND GLY-1055
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS THR-192 AND THR-598
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-939 AND SER-946;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-446; SER-815; SER-845; SER-939 AND SER-946;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-939 AND SER-946;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
"Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution." Structural genomics consortium (SGC)
Submitted (2011-08) to the PDB data bank
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Cited for: X-RAY CRYSTALLOGRAPHY (1.09 ANGSTROMS) OF 733-820 IN COMPLEX WITH ZINC
Vaild Sequence:
