Gene name:
ZHX2 (AFR1;KIAA0854;RAF) ;
Protein name:
Zinc fingers and homeoboxes protein 2 ;
Alternative:
Regulator of AFP ;Alpha-fetoprotein regulator 1 (AFP regulator 1) ;Zinc finger and homeodomain protein 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.
Function:
Acts as a transcriptional repressor.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MASKRKSTTP | CMVRTSQVVE | QDVPEEVDRA | KEKGIGTPQP | DVAKDSWAAE |
100:
LENSSKENEV | IEVKSMGESQ | SKKLQGGYEC | KYCPYSTQNL | NEFTEHVDMQ |
150:
HPNVILNPLY | VCAECNFTTK | KYDSLSDHNS | KFHPGEANFK | LKLIKRNNQT |
200:
VLEQSIETTN | HVVSITTSGP | GTGDSDSGIS | VSKTPIMKPG | KPKADAKKVP |
250:
KKPEEITPEN | HVEGTARLVT | DTAEILSRLG | GVELLQDTLG | HVMPSVQLPP |
300:
NINLVPKVPV | PLNTTKYNSA | LDTNATMINS | FNKFPYPTQA | ELSWLTAASK |
350:
HPEEHIRIWF | ATQRLKHGIS | WSPEEVEEAR | KKMFNGTIQS | VPPTITVLPA |
400:
QLAPTKVTQP | ILQTALPCQI | LGQTSLVLTQ | VTSGSTTVSC | SPITLAVAGV |
450:
TNHGQKRPLV | TPQAAPEPKR | PHIAQVPEPP | PKVANPPLTP | ASDRKKTKEQ |
500:
IAHLKASFLQ | SQFPDDAEVY | RLIEVTGLAR | SEIKKWFSDH | RYRCQRGIVH |
550:
ITSESLAKDQ | LAIAASRHGR | TYHAYPDFAP | QKFKEKTQGQ | VKILEDSFLK |
600:
SSFPTQAELD | RLRVETKLSR | REIDSWFSER | RKLRDSMEQA | VLDSMGSGKK |
650:
GQDVGAPNGA | LSRLDQLSGA | QLTSSLPSPS | PAIAKSQEQV | HLLRSTFART |
700:
QWPTPQEYDQ | LAAKTGLVRT | EIVRWFKENR | CLLKTGTVKW | MEQYQHQPMA |
750:
DDHGYDAVAR | KATKPMAESP | KNGGDVVPQY | YKDPKKLCEE | DLEKLVTRVK |
800:
VGSEPAKDCL | PAKPSEATSD | RSEGSSRDGQ | GSDENEESSV | VDYVEVTVGE |
837:
EDAISDRSDS | WSQAAAEGVS | ELAESDSDCV | PAEAGQA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Human Zinc fingers and homeoboxes protein 2
ELISA Kit for Human Zinc fingers and homeoboxes protein 2
ELISA Kit for Human Zinc fingers and homeoboxes protein 2
CLIA Kit for Human Zinc fingers and homeoboxes protein 2
CLIA Kit for Human Zinc fingers and homeoboxes protein 2
CLIA Kit for Human Zinc fingers and homeoboxes protein 2
Polyclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Polyclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Polyclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Monoclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Monoclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Monoclonal Antibody for Human Zinc fingers and homeoboxes protein 2
Protein for Human Zinc fingers and homeoboxes protein 2
Protein for Human Zinc fingers and homeoboxes protein 2
Protein for Human Zinc fingers and homeoboxes protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor."
Kawata H.
,
Yamada K.
,
Shou Z.
,
Mizutani T.
,
Yazawa T.
,
Yoshino M.
,
Sekiguchi T.
,
Kajitani T.
,
Miyamoto K.
Biochem. J.373:747-757(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;HOMODIMERIZATION;HETERODIMERIZATION WITH ZHX1 AND ZHX3;INTERACTION WITH NFYA;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lymph .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Kidney .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 524-601
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 444-501