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Index > Protein center > ZNF350(Gene name) > Human
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  • ZNF350 (Gene name),
  • Zinc finger protein 350 (Protein name ),  ZN350_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ZNF350(ZBRK1);
    Protein name:
    Zinc finger protein 350;
    Alternative:
    Zinc finger and BRCA1-interacting protein with a KRAB domain 1;KRAB zinc finger protein ZFQR;Zinc finger protein ZBRK1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with BRCA1. Interacts with RNF11.
    Function:
    Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
    Subcellular Location:
    Nucleus matrix Associated with the nuclear matrix.
    Protein Attributes:
    Sequence length:
    532
    Sequence:
    50:
    MIQAQESITL | EDVAVDFTWE | EWQLLGAAQK | DLYRDVMLEN | YSNLVAVGYQ | 
    100:
    ASKPDALFKL | EQGEQLWTIE | DGIHSGACSD | IWKVDHVLER | LQSESLVNRR | 
    150:
    KPCHEHDAFE | NIVHCSKSQF | LLGQNHDIFD | LRGKSLKSNL | TLVNQSKGYE | 
    200:
    IKNSVEFTGN | GDSFLHANHE | RLHTAIKFPA | SQKLISTKSQ | FISPKHQKTR | 
    250:
    KLEKHHVCSE | CGKAFIKKSW | LTDHQVMHTG | EKPHRCSLCE | KAFSRKFMLT | 
    300:
    EHQRTHTGEK | PYECPECGKA | FLKKSRLNIH | QKTHTGEKPY | ICSECGKGFI | 
    350:
    QKGNLIVHQR | IHTGEKPYIC | NECGKGFIQK | TCLIAHQRFH | TGKTPFVCSE | 
    400:
    CGKSCSQKSG | LIKHQRIHTG | EKPFECSECG | KAFSTKQKLI | VHQRTHTGER | 
    450:
    PYGCNECGKA | FAYMSCLVKH | KRIHTREKQE | AAKVENPPAE | RHSSLHTSDV | 
    500:
    MQEKNSANGA | TTQVPSVAPQ | TSLNISGLLA | NRNVVLVGQP | VVRCAASGDN | 
    532:
    RGFAQDRNLV | NAVNVVVPSV | INYVLFYVTE | NP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    UniGene:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zinc finger protein 350
    ELISA Kit for Human Zinc finger protein 350
    CLIA Kit for Human Zinc finger protein 350
    CLIA Kit for Human Zinc finger protein 350
    Polyclonal Antibody for Human Zinc finger protein 350
    Polyclonal Antibody for Human Zinc finger protein 350
    Monoclonal Antibody for Human Zinc finger protein 350
    Monoclonal Antibody for Human Zinc finger protein 350
    Protein for Human Zinc finger protein 350
    Protein for Human Zinc finger protein 350

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1."
      Zheng L. , Pan H. , Li S. , Flesken-Nikitin A. , Chen L.P. , Boyer G.T. , Lee H.W.
      Mol. Cell6:757-768(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS PRO-66 AND SER-501;FUNCTION;INTERACTION WITH BRCA1
    2. 2.
      "Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells."
      Ran Q. , Wadhwa R. , Bischof O. , Venable S. , Smith J.R. , Pereira-Smith O.M.
      Exp. Cell Res.263:156-162(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ILE-524;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS PRO-66 AND SER-501
      tissue: Placenta.
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    7. 7.
      "Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1."
      Wang W. , Cai J. , Wu Y. , Hu L. , Chen Z. , Hu J. , Chen Z. , Li W. , Guo M. , Huang Z.
      Cell. Mol. Life Sci.70:3947-3958(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    8. 8.
      "Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals."
      Rutter J.L. , Smith A.M. , Davila M.R. , Sigurdson A.J. , Giusti R.M. , Pineda M.A. , Doody M.M. , Tucker M.A. , Greene M.H. , Zhang J. , Struewing J.P.
      Hum. Mutat.22:121-128(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PRO-66; PRO-472; SER-501 AND ILE-524
    9. 9.
      "An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein."
      Li H. , Seth A.K.
      Oncogene23:1801-1808(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF11
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