Znf423 ELISA Kit for Mouse(Mus musculus) | EIAab.comZnf423 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Znf423(Gene name) > Mouse

Znf423 (Gene name),

Zinc finger protein 423 (Protein name ), ZN423_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Znf423(Ebfaz;Kiaa0760;Nur12;Oaz;Zfp423);

Protein name:

Zinc finger protein 423;

Alternative:

Olf1/EBF-associated zinc finger protein;Early B-cell factor-associated zinc finger protein;Smad- and Olf-interacting zinc finger protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer (By similarity). Interacts with SMAD1 and SMAD4. Interacts with EBF1 (By similarity). Interacts with PARP1.

Function:

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1292

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1292:

KLQQHIFAVH | GQEDKIYDCS | QCPQKFFFQT | ELQNHTMSQH | AQ

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:94187

UniGene:

Mm.23452

String:

Q80TS5

SMR:

Q80TS5

Pfam:

PF00096

Uniprot:

Q80TS5

FOR

ELISA Kit for Mouse Zinc finger protein 423

CLIA Kit for Mouse Zinc finger protein 423

Polyclonal Antibody for Mouse Zinc finger protein 423

Monoclonal Antibody for Mouse Zinc finger protein 423

Protein for Mouse Zinc finger protein 423

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Early B-cell factor-associated zinc-finger gene is a frequent target of retroviral integration in murine B-cell lymphomas."
Warming S. , Suzuki T. , Yamaguchi T.P. , Jenkins N.A. , Copeland N.G.
Oncogene23:2727-2731(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
strain: BALB/c.
tissue: Brain.
2.

"Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: C57BL/6.
tissue: Brain.
4.

"cDNA sequence and map assignment of Ebfaz, orthologous to the zinc finger transcription factor gene Roaz."
Croci L. , Corradi A. , Vauti F. , Wurst W. , Rocchi M. , Consalez G.G.
Submitted (1999-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 92-1292
5.

"Poly(ADP-ribose) polymerase 1 interacts with OAZ and regulates BMP-target genes."
Ku M.-C. , Stewart S. , Hata A.
Biochem. Biophys. Res. Commun.311:702-707(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARP1
6.

"Zfp423 is required for normal cerebellar development."
Warming S. , Rachel R.A. , Jenkins N.A. , Copeland N.G.
Mol. Cell. Biol.26:6913-6922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
7.

"Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation."
Alcaraz W.A. , Gold D.A. , Raponi E. , Gent P.M. , Concepcion D. , Hamilton B.A.
Proc. Natl. Acad. Sci. U.S.A.103:19424-19429(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
8.

"The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning."
Cheng L.E. , Zhang J. , Reed R.R.
Dev. Biol.307:43-52(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE
9.

"Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis."
Cheng L.E. , Reed R.R.
Neuron54:547-557(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

Product Feedback Wall

* Email:
*Comments: