Gene name:
Znf431 (Zfp431;Zfp932) ;
Protein name:
Zinc finger protein 431 ;
Alternative:
Zinc finger protein 932 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts (via KRAB domain) with HDAC2; the interaction is direct. Interacts (via KRAB domain) with HDAC1.
Function:
Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MVDALTYDDV | YVNFTQEEWA | LLNPSQKSLY | KDVMLETYRN | LNAVGYNWED |
100:
SNIEEHCESS | RRHGRHERNH | TGEKPYEGIQ | YGEAFVHHSS | LQMRKIIHTG |
150:
EKRYKCNQCD | KAYSRHSILQ | IHKRTHSGEK | PYECNQCGKA | FTQHSHLKIH |
200:
MVTHTGEKPY | KCDQCGKAFA | FHSTLQVHKR | THTGEKPYEC | NQCSKAFAHH |
250:
CHLRVHKRIH | TGEKPYKCDQ | CGKAFVGQND | LKRHERVHTG | EKPYKCNECG |
300:
KAFVCNASLR | THKTTHTGVK | PYECKQCTKS | FASHGQLQKH | ERIHTGEKPY |
350:
KCDQCGKAFA | SHDKFQKHER | IHIGEKPYKC | KQCTKSFASH | DKLQKHERIH |
400:
TGEKPYECKQ | CTKSFASHNK | LQKHERIHTG | EKPYKCDQCN | KAFVYESYLQ |
450:
VHKKTHTGEK | PYKCNECGKA | FARHSHLKVH | KITHTGEKPY | KCNQCGKALA |
500:
YHSTLQVHQR | THTGEKPYEC | EQCGKAFANQ | SYFQVHKRIH | TGEKPYKCDQ |
526:
CGKAFVGSSD | LKRHERVHTG | RETLQM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Zinc finger protein 431
ELISA Kit for Mouse Zinc finger protein 431
CLIA Kit for Mouse Zinc finger protein 431
CLIA Kit for Mouse Zinc finger protein 431
Polyclonal Antibody for Mouse Zinc finger protein 431
Polyclonal Antibody for Mouse Zinc finger protein 431
Monoclonal Antibody for Mouse Zinc finger protein 431
Monoclonal Antibody for Mouse Zinc finger protein 431
Protein for Mouse Zinc finger protein 431
Protein for Mouse Zinc finger protein 431
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH HDAC1 AND HDAC2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH HDAC2;DEVELOPMENTAL STAGE