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Index > Protein center > Znf431(Gene name) > Mouse
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  • Znf431 (Gene name),
  • Zinc finger protein 431 (Protein name ),  ZN431_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Znf431(Zfp431;Zfp932);
    Protein name:
    Zinc finger protein 431;
    Alternative:
    Zinc finger protein 932;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts (via KRAB domain) with HDAC2; the interaction is direct. Interacts (via KRAB domain) with HDAC1.
    Function:
    Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    526
    Sequence:
    50:
    MVDALTYDDV | YVNFTQEEWA | LLNPSQKSLY | KDVMLETYRN | LNAVGYNWED | 
    100:
    SNIEEHCESS | RRHGRHERNH | TGEKPYEGIQ | YGEAFVHHSS | LQMRKIIHTG | 
    150:
    EKRYKCNQCD | KAYSRHSILQ | IHKRTHSGEK | PYECNQCGKA | FTQHSHLKIH | 
    200:
    MVTHTGEKPY | KCDQCGKAFA | FHSTLQVHKR | THTGEKPYEC | NQCSKAFAHH | 
    250:
    CHLRVHKRIH | TGEKPYKCDQ | CGKAFVGQND | LKRHERVHTG | EKPYKCNECG | 
    300:
    KAFVCNASLR | THKTTHTGVK | PYECKQCTKS | FASHGQLQKH | ERIHTGEKPY | 
    350:
    KCDQCGKAFA | SHDKFQKHER | IHIGEKPYKC | KQCTKSFASH | DKLQKHERIH | 
    400:
    TGEKPYECKQ | CTKSFASHNK | LQKHERIHTG | EKPYKCDQCN | KAFVYESYLQ | 
    450:
    VHKKTHTGEK | PYKCNECGKA | FARHSHLKVH | KITHTGEKPY | KCNQCGKALA | 
    500:
    YHSTLQVHQR | THTGEKPYEC | EQCGKAFANQ | SYFQVHKRIH | TGEKPYKCDQ | 
    526:
    CGKAFVGSSD | LKRHERVHTG | RETLQM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Zinc finger protein 431
    ELISA Kit for Mouse Zinc finger protein 431
    CLIA Kit for Mouse Zinc finger protein 431
    CLIA Kit for Mouse Zinc finger protein 431
    Polyclonal Antibody for Mouse Zinc finger protein 431
    Polyclonal Antibody for Mouse Zinc finger protein 431
    Monoclonal Antibody for Mouse Zinc finger protein 431
    Monoclonal Antibody for Mouse Zinc finger protein 431
    Protein for Mouse Zinc finger protein 431
    Protein for Mouse Zinc finger protein 431

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "A novel KRAB domain-containing zinc finger transcription factor ZNF431 directly represses Patched1 transcription."
      He Z. , Cai J. , Lim J.W. , Kroll K. , Ma L.
      J. Biol. Chem.286:7279-7289(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HDAC1 AND HDAC2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    4. 4.
      "ZFP932 suppresses cellular Hedgehog response and Patched1 transcription."
      Huang G.J. , He Z. , Ma L.
      Vitam. Horm.88:309-332(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HDAC2;DEVELOPMENTAL STAGE
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