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Index > Protein center > ZRANB2(Gene name) > Human
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  • ZRANB2 (Gene name),
  • Zinc finger Ran-binding domain-containing protein 2 (Protein name ),  ZRAB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ZRANB2(ZIS;ZNF265);
    Protein name:
    Zinc finger Ran-binding domain-containing protein 2;
    Alternative:
    Zinc finger, splicing;Zinc finger protein 265;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of AKAP17A as well as with U2AF1 and CLK1.
    Function:
    Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    330
    Sequence:
    50:
    MSTKNFRVSD | GDWICPDKKC | GNVNFARRTS | CNRCGREKTT | EAKMMKAGGT | 
    100:
    EIGKTLAEKS | RGLFSANDWQ | CKTCSNVNWA | RRSECNMCNT | PKYAKLEERT | 
    150:
    GYGGGFNERE | NVEYIEREES | DGEYDEFGRK | KKKYRGKAVG | PASILKEVED | 
    200:
    KESEGEEEDE | DEDLSKYKLD | EDEDEDDADL | SKYNLDASEE | EDSNKKKSNR | 
    250:
    RSRSKSRSSH | SRSSSRSSSP | SSSRSRSRSR | SRSSSSSQSR | SRSSSRERSR | 
    300:
    SRGSKSRSSS | RSHRGSSSPR | KRSYSSSSSS | PERNRKRSRS | RSSSSGDRKK | 
    330:
    RRTRSRSPER | RHRSSSGSSH | SGSRSSSKKK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    ELISA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    ELISA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    ELISA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    ELISA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    CLIA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    CLIA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    CLIA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    CLIA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    CLIA Kit for Human Zinc finger Ran-binding domain-containing protein 2
    Polyclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Polyclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Polyclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Polyclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Polyclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Monoclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Monoclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Monoclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Monoclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Monoclonal Antibody for Human Zinc finger Ran-binding domain-containing protein 2
    Protein for Human Zinc finger Ran-binding domain-containing protein 2
    Protein for Human Zinc finger Ran-binding domain-containing protein 2
    Protein for Human Zinc finger Ran-binding domain-containing protein 2
    Protein for Human Zinc finger Ran-binding domain-containing protein 2
    Protein for Human Zinc finger Ran-binding domain-containing protein 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene."
      Nakano M. , Yoshiura K. , Oikawa M. , Miyoshi O. , Yamada K. , Kondo S. , Miwa N. , Soeda E. , Jinno Y. , Fujii T. , Niikawa N.
      Gene225:59-65(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Fetal brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Uterus.
    3. 3.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    4. 4.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Liver.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLY-207
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLY-207
      tissue: Skin.
    8. 8.
      "ZNF265 -- a novel spliceosomal protein able to induce alternative splicing."
      Adams D.J. , van der Weyden L. , Mayeda A. , Stamm S. , Morris B.J. , Rasko J.E.J.
      J. Cell Biol.154:25-32(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH SNRNP70; U2AF1 AND CLK1
    9. 9.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120; SER-153; SER-181; SER-188 AND SER-193;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265."
      Mangs A.H. , Speirs H.J.L. , Goy C. , Adams D.J. , Markus M.A. , Morris B.J.
      Nucleic Acids Res.34:4976-4986(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AKAP17A
    11. 11.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305; SER-307 AND SER-310 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    12. 12.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120; SER-153; SER-181 AND SER-188;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-303; SER-305; SER-307 AND SER-310 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    14. 14.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120 AND SER-153;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    15. 15.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120 AND SER-188;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305 AND SER-307 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    17. 17.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9; SER-120; SER-153; SER-181; SER-188 AND SER-193;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305; SER-307 AND SER-310 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    20. 20.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120; SER-153; SER-181; SER-188 AND SER-193;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-303; SER-305 AND SER-307 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    21. 21.
      "The structure of the zinc finger domain from human splicing factor ZNF265 fold."
      Plambeck C.A. , Kwan A.H.Y. , Adams D.J. , Westman B.J. , van der Weyden L. , Medcalf R.L. , Morris B.J. , Mackay J.P.
      J. Biol. Chem.278:22805-22811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-40;RNA-BINDING
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