ZRANB3 ELISA Kit for Bovine(Bos taurus) | EIAab.comZRANB3 ELISA Kit for Bovine(Bos taurus)

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ZRANB3 (Gene name),

DNA annealing helicase and endonuclease ZRANB3 (Protein name ), ZRAB3_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ZRANB3;

Protein name:

DNA annealing helicase and endonuclease ZRANB3;

Alternative:

Zinc finger Ran-binding domain-containing protein 3;Annealing helicase 2(AH2);

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts (via PIP-box and RanBP2-type zinc finger) with PCNA (when PCNA is polyubiquitinated via 'Lys-63'-linked polyubiquitin).

Function:

DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.

Subcellular Location:

Nucleus Chromosome Following DNA damage, recruited to sites of DNA damage and stalled replication forks by polyubiquitinated PCNA.

Protein Attributes:

Sequence length:

1074

Sequence:

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1050:

1074:

RSQVRRQSLA | SNHGSDITRF | LVKK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00271

Uniprot:

E1BB03

FOR

ELISA Kit for Bovine DNA annealing helicase and endonuclease ZRANB3

CLIA Kit for Bovine DNA annealing helicase and endonuclease ZRANB3

Polyclonal Antibody for Bovine DNA annealing helicase and endonuclease ZRANB3

Monoclonal Antibody for Bovine DNA annealing helicase and endonuclease ZRANB3

Protein for Bovine DNA annealing helicase and endonuclease ZRANB3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V. , Delcher A.L. , Florea L. , Kelley D.R. , Schatz M.C. , Puiu D. , Hanrahan F. , Pertea G. , Van Tassell C.P. , Sonstegard T.S. , Marcais G. , Roberts M. , Subramanian P. , Yorke J.A. , Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Hereford.

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