Protein name:
ZW10 interactor ;
Alternative:
ZW10-interacting protein 1 (Zwint-1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with ZW10 and MIS12. Interacts with the NDC80 subunit of the NDC80 complex specifically during mitosis. Also interacts with CASC5, CETN3, DSN1 and PMF1.
Function:
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
Subcellular Location:
Nucleus
Chromosome
centromere
kinetochore
Localizes to kinetochores from late prophase to anaphase.
Protein Attributes:
50:
MEAAETEAEA | AALEVLAEVA | GILEPVGLQE | EAELPAKILV | EFVVDSQKKD |
100:
KLLCSQLQVA | DFLQNILAQE | DTAKGLDPLA | SEDTSRQKAI | AAKEQWKELK |
150:
ATYREHVEAI | KIGLTKALTQ | MEEAQRKRTQ | LREAFEQLQA | KKQMAMEKRR |
200:
AVQNQWQLQQ | EKHLQHLAEV | SAEVRERKTG | TQQELDRVFQ | KLGNLKQQAE |
250:
QERDKLQRYQ | TFLQLLYTLQ | GKLLFPEAEA | EAENLPDDKP | QQPTRPQEQS |
277:
TGDTMGRDPG | VSFKAVGLQP | AGDVNLP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
Bovine
ELISA Kit for Human ZW10 interactor
ELISA Kit for Human ZW10 interactor
ELISA Kit for Human ZW10 interactor
ELISA Kit for Human ZW10 interactor
CLIA Kit for Human ZW10 interactor
CLIA Kit for Human ZW10 interactor
CLIA Kit for Human ZW10 interactor
CLIA Kit for Human ZW10 interactor
Polyclonal Antibody for Human ZW10 interactor
Polyclonal Antibody for Human ZW10 interactor
Polyclonal Antibody for Human ZW10 interactor
Polyclonal Antibody for Human ZW10 interactor
Monoclonal Antibody for Human ZW10 interactor
Monoclonal Antibody for Human ZW10 interactor
Monoclonal Antibody for Human ZW10 interactor
Monoclonal Antibody for Human ZW10 interactor
Protein for Human ZW10 interactor
Protein for Human ZW10 interactor
Protein for Human ZW10 interactor
Protein for Human ZW10 interactor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-187
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"The DNA sequence and comparative analysis of human chromosome 10."
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more...
Nature429:375-381(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-187
tissue :
Colon .
tissue :
Lymph .
tissue :
Muscle .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
"Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling."
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J. Biol. Chem.279:54590-54598(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH ZW10;SUBCELLULAR LOCATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH MIS12;SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH CASC5; CETN3; DSN1; NDC80; MIS12; PMFF1 AND ZW10;SUBCELLULAR LOCATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH NDC80 AND ZW10;SUBCELLULAR LOCATION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]