Language:
  
[Sign in] [Register]   

EIAab logo

EIAab news detail, please contact eiaab@eiaab.com if you have any questions about online orders and payment.
Effect of milk yield on functional activity of neutrophil in crossbred Karan Fries (Holstein Friesian X Tharparkar) cows around peripartum
Update time:2016-07-28 01:31:00   【 Font: Large  Medium Small

Abstract

To study the immunological activities of neutrophils, blood samples were collected from 6 high yielding (HY) and 6 low yielding (LY) Karan Fries (KF) cows on -15,-7, -5, -3, -2, -1 days prepartum, at calving and on 1, 2, 3, 5, 7 and 15 days postpartum. Plasma cortisol levels, phagocytic activity (PA), enzyme (Elastase, Collagenase and Cathepsin G) levels and expression of TLR-2, TLR-4 and IL-8 were also studied. Both HY KF and LY KF cows were found to have increased blood Total leukocyte counts (TLC) and neutrophil percent at calving, but HY KF cows had significantly (P<0.05) higher levels than LY KF cows. The number of band neutrophils were also significantly (P<0.05) higher in HY cows. Significant (P<0.05) immunosuppression in relation to PA was found for HY as compared to LY KF cows throughout the peripartum period, with the lowest immunosuppression at calving in both groups of cows. Cortisol levels were significantly (P<0.01) higher during calving and negatively correlated with neutrophilic functions. The difference between the two groups also remained significant (P<0.05) as higher level of cortisol were found in HY KF cows. Elastase, collagenase and cathepsin were significantly (P<0.05) decreased during parturition. Elastase was reduced approximately 2.5 times on the day of calving in LY KF cows, but no such major reduction was observed for HY KF cows. Collagenase and cathepsin levels were significantly (P<0.05) higher in LY cows. Expression of the TLR-2 gene was significantly (P<0.05) lower in HY cows during the whole peripartum period than in LY cows. Expression of the TLR-4 gene was significantly (P<0.05) lower on days 15 pre- and post-calving in HY cows. IL-8 differed significantly (P<0.05) only during the prepartum days. Lower neutrophilic function in cross bred cows with high production potential, provides lower disease resistance and makes the cows more susceptible to peripartum infection.

 

Cited products
Source:VETERINARSKI ARHIV      by Pathan M M, Kaur M, Mohanty A K, et al.
Hot Genes
Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
Top Searches
Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Tumor necrosis Alpha Asprosin TRAP1A
Why choose EIAAB
Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
Further Information
About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

鄂ICP备10015095号-1

鄂公网安备 42018502005535号

Twitter