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Index > Protein center > ADORA2A(Gene name) > Human
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  • ADORA2A (Gene name),
  • Adenosine receptor A2a (Protein name ),  AA2AR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ADORA2A(ADORA2);
    Protein name:
    Adenosine receptor A2a;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (via cytoplasmic C-terminal domain) with USP4; the interaction is direct. May interact with DRD4.
    Function:
    Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    412
    Sequence:
    50:
    MPIMGSSVYI | TVELAIAVLA | ILGNVLVCWA | VWLNSNLQNV | TNYFVVSLAA | 
    100:
    ADIAVGVLAI | PFAITISTGF | CAACHGCLFI | ACFVLVLTQS | SIFSLLAIAI | 
    150:
    DRYIAIRIPL | RYNGLVTGTR | AKGIIAICWV | LSFAIGLTPM | LGWNNCGQPK | 
    200:
    EGKNHSQGCG | EGQVACLFED | VVPMNYMVYF | NFFACVLVPL | LLMLGVYLRI | 
    250:
    FLAARRQLKQ | MESQPLPGER | ARSTLQKEVH | AAKSLAIIVG | LFALCWLPLH | 
    300:
    IINCFTFFCP | DCSHAPLWLM | YLAIVLSHTN | SVVNPFIYAY | RIREFRQTFR | 
    350:
    KIIRSHVLRQ | QEPFKAAGTS | ARVLAAHGSD | GEQVSLRLNG | HPPGVWANGS | 
    400:
    APHPERRPNG | YALGLVSGGS | AQESQGNTGL | PDVELLSHEL | KGVCPEPPGL | 
    412:
    DDPLAQDGAG | VS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    SMR:
    UniGene:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Adenosine receptor A2a
    Cat.:
    E12274h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Adenosine receptor A2a
    Cat.:
    E12274m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Adenosine receptor A2a
    MSDS:
    Please sign in first.
    ELISA Kit for Human Adenosine receptor A2a
    Cat.:
    E12274r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Adenosine receptor A2a
    Cat.:
    U12274r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Adenosine receptor A2a
    MSDS:
    Please sign in first.
    CLIA Kit for Human Adenosine receptor A2a
    Cat.:
    U12274m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Adenosine receptor A2a
    Cat.:
    U12274h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Adenosine receptor A2a
    Polyclonal Antibody for Human Adenosine receptor A2a
    Polyclonal Antibody for Human Adenosine receptor A2a
    Cat.:
    P12274Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Adenosine receptor A2a
    Monoclonal Antibody for Human Adenosine receptor A2a
    Monoclonal Antibody for Human Adenosine receptor A2a
    Monoclonal Antibody for Human Adenosine receptor A2a
    Monoclonal Antibody for Human Adenosine receptor A2a
    Protein for Human Adenosine receptor A2a
    Protein for Human Adenosine receptor A2a
    Protein for Human Adenosine receptor A2a
    Protein for Human Adenosine receptor A2a

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Tiffany H.L. , Murphy P.M.
      Submitted (1992-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Salvatore C.A. , Luneau C.J. , Johnson R.G. , Jacobson M.
      Submitted (1992-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "Molecular characterization of a human brain adenosine A2 receptor."
      Furlong T.J. , Pierce K.D. , Selbie L.A. , Shine J.
      Brain Res. Mol. Brain Res.15:62-66(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Hippocampus.
    4. 4.
      "Characterization and chromosomal localization of the human A2a adenosine receptor gene: ADORA2A."
      Le F. , Townsend-Nicholson A. , Baker E. , Sutherland G.R. , Schofield P.R.
      Biochem. Biophys. Res. Commun.223:461-467(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
      Submitted (2002-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thymus.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lymph.
    11. 11.
      "The dopamine D(4) receptor, the ultimate disordered protein."
      Woods A.S.
      J. Recept. Signal Transduct.30:331-336(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INTERACTION WITH DRD4
    12. 12.
      "Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor."
      Kim J. , Wess J. , van Rhee A.M. , Schoneberg T. , Jacobson K.A.
      J. Biol. Chem.270:13987-13997(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF TRANSMEMBRANE DOMAINS
    13. 13.
      "The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor."
      Milojevic T. , Reiterer V. , Stefan E. , Korkhov V.M. , Dorostkar M.M. , Ducza E. , Ogris E. , Boehm S. , Freissmuth M. , Nanoff C.
      Mol. Pharmacol.69:1083-1094(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH USP4;UBIQUITINATION;DEUBIQUITINATION BY USP4
    14. 14.
      "The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist."
      Jaakola V.-P. , Griffith M.T. , Hanson M.A. , Cherezov V. , Chien E.Y.T. , Lane J.R. , Ijzerman A.P. , Stevens R.C.
      Science322:1211-1217(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 2-316 IN COMPLEX WITH ANTAGONIST;TOPOLOGY;DISULFIDE BONDS
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VAL-50
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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